Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7124
Gene Symbol: TNF
TNF
tumor necrosis factor 0.263 0.966 0.80
Chemical and Drug Induced Liver Injury
disease 0.300 6 0 1995 2012
Entrez Id: 3569
Gene Symbol: IL6
IL6
interleukin 6 0.287 0.966 0.34
Chemical and Drug Induced Liver Injury
disease 0.300 2 0 1995 2005
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
interleukin 1 beta 0.312 0.931 0.13
Chemical and Drug Induced Liver Injury
disease 0.300 2 0 2009 2018
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
interferon gamma 0.323 0.897 0.47
Chemical and Drug Induced Liver Injury
disease 0.300 2 0 2002 2011
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
prostaglandin-endoperoxide synthase 2 0.338 0.897 1.00
Chemical and Drug Induced Liver Injury
disease 0.300 1 0 2002 2002
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
major histocompatibility complex, class II, DR beta 1 0.347 0.897 1.0E-03
Chemical and Drug Induced Liver Injury
disease 0.300 1 0 2011 2011
Entrez Id: 348
Gene Symbol: APOE
APOE
apolipoprotein E 0.352 0.931 1.7E-03
Chemical and Drug Induced Liver Injury
disease 0.300 1 0 2006 2006
Entrez Id: 6347
Gene Symbol: CCL2
CCL2
C-C motif chemokine ligand 2 0.353 0.897 0.62
Chemical and Drug Induced Liver Injury
disease 0.300 1 0 2011 2011
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
methylenetetrahydrofolate reductase 0.354 0.828 1.2E-09
Chemical and Drug Induced Liver Injury
disease 0.300 2 0 2008 2011
Entrez Id: 3479
Gene Symbol: IGF1
IGF1
insulin like growth factor 1 0.355 0.828 0.29
Chemical and Drug Induced Liver Injury
disease 0.300 2 0 2014 2015
Entrez Id: 3565
Gene Symbol: IL4
IL4
interleukin 4 0.364 0.931 5.3E-03
Chemical and Drug Induced Liver Injury
disease 0.300 2 0 2011 2012
Entrez Id: 3552
Gene Symbol: IL1A
IL1A
interleukin 1 alpha 0.366 0.931 1.5E-04
Chemical and Drug Induced Liver Injury
disease 0.300 1 0 1993 1993
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
ATP binding cassette subfamily B member 1 0.371 0.828 1.3E-05
Chemical and Drug Induced Liver Injury
disease 0.500 1 0 2011 2016
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
matrix metallopeptidase 2 0.373 0.862 0.84
Chemical and Drug Induced Liver Injury
disease 0.300 1 0 2005 2005
Entrez Id: 3605
Gene Symbol: IL17A
IL17A
interleukin 17A 0.391 0.862 4.4E-02
Chemical and Drug Induced Liver Injury
disease 0.300 2 0 2009 2015
Entrez Id: 6696
Gene Symbol: SPP1
SPP1
secreted phosphoprotein 1 0.391 0.862 1.0E-06
Chemical and Drug Induced Liver Injury
disease 0.300 1 0 2011 2011
Entrez Id: 6648
Gene Symbol: SOD2
SOD2
superoxide dismutase 2 0.396 0.897 0.16
Chemical and Drug Induced Liver Injury
disease 0.300 1 0 2015 2015
Entrez Id: 847
Gene Symbol: CAT
CAT
catalase 0.397 0.828 1.9E-10
Chemical and Drug Induced Liver Injury
disease 0.300 1 0 2011 2011
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
glutathione S-transferase mu 1 0.403 0.828 2.0E-03
Chemical and Drug Induced Liver Injury
disease 0.300 2 0 2007 2008
Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1
heme oxygenase 1 0.403 0.862 7.9E-03
Chemical and Drug Induced Liver Injury
disease 0.300 2 0 2008 2012
Entrez Id: 3105
Gene Symbol: HLA-A
HLA-A
major histocompatibility complex, class I, A 0.404 0.793 5.8E-03
Chemical and Drug Induced Liver Injury
disease 0.300 2 0 2011 2017
Entrez Id: 3606
Gene Symbol: IL18
IL18
interleukin 18 0.404 0.862 2.9E-02
Chemical and Drug Induced Liver Injury
disease 0.300 1 0 2009 2009
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
glutathione S-transferase pi 1 0.406 0.828 7.1E-02
Chemical and Drug Induced Liver Injury
disease 0.300 2 0 2011 2015
Entrez Id: 6647
Gene Symbol: SOD1
SOD1
superoxide dismutase 1 0.406 0.931 0.13
Chemical and Drug Induced Liver Injury
disease 0.300 2 0 2011 2017
Entrez Id: 406991
Gene Symbol: MIR21
MIR21
microRNA 21 0.407 0.759
Chemical and Drug Induced Liver Injury
disease 0.300 1 0 2017 2017