Source: LHGDN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis 		0.400 GeneticVariation LHGDN Our results suggested that though TNF-alpha G-238A and G-308A polymorphisms were not involved in the pathogenesis of type 2 DM, type 2 diabetic patients carrying TNFA-A or TNF-308*2 genotype might be more susceptible to diabetic complications such as atherosclerosis. 12753658

2003
Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis 		0.400 AlteredExpression LHGDN Enhanced TNF-alpha production may also promote atherosclerosis due to increased insulin resistance and the expression of adhesion molecules. 14630568

2004
Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis 		0.400 Biomarker LHGDN Tumor necrosis factor (TNF)-alpha-induced endothelial injury, which is associated with atherosclerosis, is mediated by intracellular reactive oxygen species. 16224057

2005
Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis 		0.400 AlteredExpression LHGDN HIV protease inhibitors increase TNF-alpha and IL-6 expression in macrophages: involvement of the RNA-binding protein HuR. 17531241

2007