| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
sirtuin 1 | 0.378 | 0.885 | 8.7E-02 |
|
phenotype | 0.100 | None | 1.000 | 90 | 0 | 2005 | 2020 | ||||||||
|
mitogen-activated protein kinase 1 | 0.330 | 0.923 | 1.00 |
|
phenotype | 0.100 | None | 1.000 | 82 | 1 | 1994 | 2019 | ||||||||
|
MET proto-oncogene, receptor tyrosine kinase | 0.380 | 0.846 | 0.97 |
|
phenotype | 0.100 | None | 1.000 | 74 | 1 | 1991 | 2020 | ||||||||
|
mechanistic target of rapamycin kinase | 0.343 | 0.885 | 1.00 |
|
phenotype | 0.100 | None | 1.000 | 71 | 0 | 2001 | 2020 | ||||||||
|
SRY-box transcription factor 2 | 0.405 | 0.808 | 0.71 |
|
phenotype | 0.100 | None | 1.000 | 69 | 0 | 2006 | 2020 | ||||||||
|
EPH receptor B2 | 0.374 | 0.846 | 1.00 |
|
phenotype | 0.100 | None | 1.000 | 67 | 2 | 1994 | 2019 | ||||||||
|
ATM serine/threonine kinase | 0.374 | 0.885 | 5.6E-47 |
|
phenotype | 0.100 | None | 1.000 | 61 | 1 | 1995 | 2019 | ||||||||
|
isocitrate dehydrogenase (NADP(+)) 1 | 0.424 | 0.808 | 2.6E-12 |
|
phenotype | 0.100 | None | 1.000 | 56 | 1 | 2009 | 2020 | ||||||||
|
high mobility group AT-hook 2 | 0.429 | 0.808 | 0.87 |
|
phenotype | 0.100 | None | 1.000 | 53 | 0 | 1996 | 2020 | ||||||||
|
toll like receptor 4 | 0.321 | 0.962 | 4.6E-09 |
|
phenotype | 0.100 | None | 1.000 | 51 | 1 | 2007 | 2020 | ||||||||
|
Kruppel like factor 4 | 0.449 | 0.769 | 1.00 |
|
phenotype | 0.100 | None | 1.000 | 51 | 0 | 2003 | 2019 | ||||||||
|
eukaryotic translation initiation factor 4E | 0.448 | 0.846 | 0.94 |
|
phenotype | 0.100 | None | 1.000 | 47 | 0 | 1999 | 2020 | ||||||||
|
adiponectin, C1Q and collagen domain containing | 0.376 | 0.885 | 4.6E-09 |
|
phenotype | 0.100 | None | 1.000 | 43 | 1 | 2006 | 2020 | ||||||||
|
insulin like growth factor 1 receptor | 0.399 | 0.885 | 0.97 |
|
phenotype | 0.100 | None | 1.000 | 42 | 0 | 1994 | 2019 | ||||||||
|
E2F transcription factor 1 | 0.441 | 0.846 | 0.99 |
|
phenotype | 0.100 | None | 1.000 | 41 | 0 | 1998 | 2019 | ||||||||
|
metadherin | 0.491 | 0.769 | 0.33 |
|
phenotype | 0.100 | None | 1.000 | 41 | 0 | 2007 | 2019 | ||||||||
|
cytochrome P450 family 1 subfamily A member 1 | 0.436 | 0.846 | 1.1E-17 |
|
phenotype | 0.100 | None | 1.000 | 40 | 3 | 1981 | 2019 | ||||||||
|
estrogen receptor 2 | 0.400 | 0.923 | 4.5E-08 |
|
phenotype | 0.100 | None | 1.000 | 39 | 0 | 2002 | 2020 | ||||||||
|
protein tyrosine phosphatase non-receptor type 11 | 0.385 | 0.923 | 1.00 |
|
phenotype | 0.100 | None | 1.000 | 39 | 1 | 2005 | 2019 | ||||||||
|
C-X-C motif chemokine ligand 8 | 0.310 | 0.962 | 2.7E-04 |
|
phenotype | 0.100 | None | 1.000 | 38 | 1 | 1998 | 2020 | ||||||||
|
matrix metallopeptidase 9 | 0.305 | 0.923 | 1.9E-17 |
|
phenotype | 0.100 | None | 1.000 | 38 | 0 | 2001 | 2019 | ||||||||
|
Rac family small GTPase 1 | 0.429 | 0.962 | 0.76 |
|
phenotype | 0.100 | None | 1.000 | 38 | 1 | 1999 | 2019 | ||||||||
|
actin beta | 0.325 | 0.923 | 0.99 |
|
phenotype | 0.100 | None | 1.000 | 37 | 0 | 1982 | 2019 | ||||||||
|
C-X-C motif chemokine receptor 4 | 0.362 | 0.923 | 1.8E-02 |
|
phenotype | 0.100 | None | 1.000 | 37 | 0 | 2003 | 2019 | ||||||||
|
WW domain containing oxidoreductase | 0.453 | 0.808 | 1.2E-15 |
|
phenotype | 0.100 | None | 1.000 | 36 | 0 | 2001 | 2018 |