Source: ALL

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53
tumor protein p53 0.251 0.897 0.17
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
phenotype 0.100 0.944 953 10 1991 2018
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
cyclin dependent kinase inhibitor 2A 0.321 0.828 0.38
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
phenotype 0.400 0.899 308 0 1994 2018
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
prostaglandin-endoperoxide synthase 2 0.338 0.897 1.00
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
phenotype 0.100 0.969 223 0 1996 2018
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
epidermal growth factor receptor 0.325 0.862 0.50
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
phenotype 0.100 0.938 210 2 1986 2018
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
erb-b2 receptor tyrosine kinase 2 0.352 0.862 1.8E-03
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
phenotype 0.400 0.953 192 0 1989 2018
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha 0.341 0.897 1.00
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
phenotype 0.100 0.982 167 1 2000 2018
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
phosphatase and tensin homolog 0.334 0.828 0.82
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
phenotype 0.100 0.946 166 0 1997 2018
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
BRCA1, DNA repair associated 0.410 0.862 1.8E-28
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
phenotype 0.100 0.958 144 1 1994 2016
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
signal transducer and activator of transcription 3 0.358 0.862 1.00
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
phenotype 0.100 0.986 140 0 2000 2018
Entrez Id: 324
Gene Symbol: APC
APC
APC, WNT signaling pathway regulator 0.397 0.828 1.00
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
phenotype 0.100 0.971 139 2 1990 2016
Entrez Id: 595
Gene Symbol: CCND1
CCND1
cyclin D1 0.365 0.828 0.90
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
phenotype 0.100 0.978 137 0 1992 2018
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
KRAS proto-oncogene, GTPase 0.350 0.724 9.0E-04
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
phenotype 0.400 0.953 130 3 1990 2018
Entrez Id: 4609
Gene Symbol: MYC
MYC
MYC proto-oncogene, bHLH transcription factor 0.382 0.724 1.00
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
phenotype 0.100 0.984 125 0 1984 2018
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma 0.385 0.862 1.5E-06
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
phenotype 0.100 0.992 122 0 2000 2018
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta 0.389 0.862 1.00
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
phenotype 0.100 0.992 121 1 2000 2018
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta 0.386 0.862 1.00
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
phenotype 0.100 0.992 120 0 2000 2018
Entrez Id: 673
Gene Symbol: BRAF
BRAF
B-Raf proto-oncogene, serine/threonine kinase 0.352 0.793 1.00
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
phenotype 0.400 0.873 118 1 2003 2018
Entrez Id: 4193
Gene Symbol: MDM2
MDM2
MDM2 proto-oncogene 0.396 0.759 1.00
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
phenotype 0.100 0.955 110 2 1994 2017
Entrez Id: 207
Gene Symbol: AKT1
AKT1
AKT serine/threonine kinase 1 0.355 0.862 0.98
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
phenotype 0.100 0.991 106 1 2000 2018
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
estrogen receptor 1 0.355 0.897 1.00
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
phenotype 0.100 0.935 93 1 1997 2018
Entrez Id: 4513
Gene Symbol: COX2
COX2
cytochrome c oxidase subunit II 0.397 0.862
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
phenotype 0.100 0.966 87 0 1999 2018
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
vascular endothelial growth factor A 0.298 0.897 2.7E-05
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
phenotype 0.100 0.988 84 0 1995 2017
Entrez Id: 367
Gene Symbol: AR
AR
androgen receptor 0.380 0.793 0.98
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
phenotype 0.100 0.974 77 0 1997 2018
Entrez Id: 596
Gene Symbol: BCL2
BCL2
BCL2, apoptosis regulator 0.312 0.862 0.57
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
phenotype 0.100 0.895 76 1 1991 2018
Entrez Id: 2146
Gene Symbol: EZH2
EZH2
enhancer of zeste 2 polycomb repressive complex 2 subunit 0.421 0.759 1.00
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis
phenotype 0.100 1.000 75 1 2004 2018