Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7166
Gene Symbol: TPH1
TPH1
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.400 Biomarker PSYGENET In addition, TPH1 gene is most likely to have a shared effect on aggression and MDD. 22697203

2012

Entrez Id: 7166
Gene Symbol: TPH1
TPH1
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.400 Biomarker PSYGENET The A allele at TPH1 rs1800532 may be associated with citalopram efficacy only in melancholic and psychotic MDD. 23221997

2013

Entrez Id: 7166
Gene Symbol: TPH1
TPH1
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.400 Biomarker PSYGENET However, the relationship between temperament and TPH1 genotype in major depression is poorly understood, as only one study has been published so far. 23597148

2013

Entrez Id: 7166
Gene Symbol: TPH1
TPH1
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.400 Biomarker PSYGENET We detected allelic or genotypic associations of MAOA, TPH1, FKBP5 and BDNF in clinically significant MDD in AD. 23157339

2013

Entrez Id: 7166
Gene Symbol: TPH1
TPH1
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.400 Biomarker PSYGENET Our results suggest that TPH1 218A/C and HTR5A 12A/T polymorphisms cannot predict treatment response in major depression. 24903772

2014