Source: LHGDN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3586
Gene Symbol: IL10
IL10
CUI: C0007273
Disease: Carotid Artery Diseases
Carotid Artery Diseases
0.010 GeneticVariation LHGDN Relationship between -592A/C polymorphism of interleukin-10 (IL-10) gene and risk of early carotid atherosclerosis. 19118909

2010

Entrez Id: 1116
Gene Symbol: CHI3L1
CHI3L1
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
0.010 AlteredExpression LHGDN Pretreatment serum YKL-40 level is a possible prognosticator of cervical adenocarcinoma. 18723551

2009

Entrez Id: 4548
Gene Symbol: MTR
MTR
CUI: C0001430
Disease: Adenoma
Adenoma
0.010 Biomarker LHGDN Methionine synthase A2756G polymorphism interacts with alcohol and folate intake to influence the risk of colorectal adenoma. 19124508

2009

Entrez Id: 6550
Gene Symbol: SLC9A3
SLC9A3
CUI: C0001430
Disease: Adenoma
Adenoma
0.010 AlteredExpression LHGDN Functional coupling of the downregulated in adenoma Cl-/base exchanger DRA and the apical Na+/H+ exchangers NHE2 and NHE3. 19056765

2009

Entrez Id: 6497
Gene Symbol: SKI
SKI
CUI: C0001430
Disease: Adenoma
Adenoma
0.010 AlteredExpression LHGDN TGF-beta repressors SnoN and Ski are implicated in human colorectal carcinogenesis. 19096149

2009

Entrez Id: 6549
Gene Symbol: SLC9A2
SLC9A2
CUI: C0001430
Disease: Adenoma
Adenoma
0.010 AlteredExpression LHGDN Functional coupling of the downregulated in adenoma Cl-/base exchanger DRA and the apical Na+/H+ exchangers NHE2 and NHE3. 19056765

2009

Entrez Id: 6498
Gene Symbol: SKIL
SKIL
CUI: C0001430
Disease: Adenoma
Adenoma
0.010 AlteredExpression LHGDN TGF-beta repressors SnoN and Ski are implicated in human colorectal carcinogenesis. 19096149

2009

Entrez Id: 701
Gene Symbol: BUB1B
BUB1B
CUI: C0001618
Disease: Tumors of Adrenal Cortex
Tumors of Adrenal Cortex
0.010 AlteredExpression LHGDN Gene expression profiling reveals a new classification of adrenocortical tumors and identifies molecular predictors of malignancy and survival. 19139432

2009

Entrez Id: 9787
Gene Symbol: DLGAP5
DLGAP5
CUI: C0001618
Disease: Tumors of Adrenal Cortex
Tumors of Adrenal Cortex
0.010 AlteredExpression LHGDN Gene expression profiling reveals a new classification of adrenocortical tumors and identifies molecular predictors of malignancy and survival. 19139432

2009

Entrez Id: 65018
Gene Symbol: PINK1
PINK1
CUI: C0001618
Disease: Tumors of Adrenal Cortex
Tumors of Adrenal Cortex
0.010 AlteredExpression LHGDN Gene expression profiling reveals a new classification of adrenocortical tumors and identifies molecular predictors of malignancy and survival. 19139432

2009

Entrez Id: 3952
Gene Symbol: LEP
LEP
CUI: C0001627
Disease: Congenital adrenal hyperplasia
Congenital adrenal hyperplasia
0.010 Biomarker LHGDN Does an altered leptin axis play a role in obesity among children and adolescents with classical congenital adrenal hyperplasia due to 21-hydroxylase deficiency? 19004982

2009

Entrez Id: 4599
Gene Symbol: MX1
MX1
CUI: C0001752
Disease: African swine fever
African swine fever
0.010 Biomarker LHGDN Inhibition of a large double-stranded DNA virus by MxA protein. 19109387

2009

Entrez Id: 4162
Gene Symbol: MCAM
MCAM
CUI: C0001815
Disease: Primary Myelofibrosis
Primary Myelofibrosis
0.010 Biomarker LHGDN Our data providing evidence of CD146(+) cell involvement in bone marrow stromal changes occurring in primary myelofibrosis are consistent with the capability of these cells to participate in fiber deposition, angiogenesis, and bone formation. 19029148

2009

Entrez Id: 3592
Gene Symbol: IL12A
IL12A
CUI: C0002390
Disease: Extrinsic allergic alveolitis
Extrinsic allergic alveolitis
0.010 Biomarker LHGDN Interleukin 12, interleukin 18, and tumor necrosis factor alpha release by alveolar macrophages: acute and chronic hypersensitivity pneumonitis. 19230467

2009

Entrez Id: 3606
Gene Symbol: IL18
IL18
CUI: C0002390
Disease: Extrinsic allergic alveolitis
Extrinsic allergic alveolitis
0.010 Biomarker LHGDN The levels of IL-12, IL-18, and TNF-alpha showed no difference between patients with acute and chronic HP. 19230467

2009

Entrez Id: 5697
Gene Symbol: PYY
PYY
CUI: C0002453
Disease: Amenorrhea
Amenorrhea
0.010 Biomarker LHGDN Elevated PYY is associated with energy deficiency and indices of subclinical disordered eating in exercising women with hypothalamic amenorrhea. 18929607

2009

Entrez Id: 4982
Gene Symbol: TNFRSF11B
TNFRSF11B
CUI: C0002453
Disease: Amenorrhea
Amenorrhea
0.010 Biomarker LHGDN The effect of exercise and estrogen on osteoprotegerin in premenopausal women. 18929691

2009

Entrez Id: 7857
Gene Symbol: SCG2
SCG2
CUI: C0002736
Disease: Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis
0.010 Biomarker LHGDN Eight cases of ALS and seven control cases were studied with semiquantitative immunocytochemistry for chromogranin A, chromogranin B and secretogranin II that are soluble constituents of large dense core vesicles, synaptophysin as a membrane protein of small synaptic vesicles and superoxide dismutase 1. 18721831

2009

Entrez Id: 1378
Gene Symbol: CR1
CR1
CUI: C0002880
Disease: Autoimmune hemolytic anemia
Autoimmune hemolytic anemia
0.010 AlteredExpression LHGDN In addition, we detected that patients with active wAIHA present low expression of CD59 and normal expression of CD35 and CD55 on their RBCs. 18954403

2009

Entrez Id: 1604
Gene Symbol: CD55
CD55
CUI: C0002880
Disease: Autoimmune hemolytic anemia
Autoimmune hemolytic anemia
0.010 AlteredExpression LHGDN In addition, we detected that patients with active wAIHA present low expression of CD59 and normal expression of CD35 and CD55 on their RBCs. 18954403

2009

Entrez Id: 966
Gene Symbol: CD59
CD59
CUI: C0002880
Disease: Autoimmune hemolytic anemia
Autoimmune hemolytic anemia
0.010 AlteredExpression LHGDN In addition, we detected that patients with active wAIHA present low expression of CD59 and normal expression of CD35 and CD55 on their RBCs. 18954403

2009

Entrez Id: 1356
Gene Symbol: CP
CP
CUI: C0002965
Disease: Angina, Unstable
Angina, Unstable
0.010 Biomarker LHGDN Ceruloplasmin is a better predictor of the long-term prognosis compared with fibrinogen, CRP, and IL-6 in patients with severe unstable angina. 18388036

2009

Entrez Id: 1080
Gene Symbol: CFTR
CFTR
CUI: C0003130
Disease: Anoxia
Anoxia
0.010 AlteredExpression LHGDN Since hypoxia alters stimulated Cl(-) and water flux, we investigated the influence of such a physiologically and pathophysiologically important signal on expression of the cystic fibrosis transmembrane conductance regulator (CFTR). 18779379

2009

Entrez Id: 2734
Gene Symbol: GLG1
GLG1
CUI: C0003130
Disease: Anoxia
Anoxia
0.010 AlteredExpression LHGDN While the expression of the glycoprotein CFR was unaffected by hypoxia, the cell-associated E-selectin binding activity decreased. 19148508

2009

Entrez Id: 4582
Gene Symbol: MUC1
MUC1
CUI: C0003130
Disease: Anoxia
Anoxia
0.010 AlteredExpression LHGDN These data suggest that hypoxia enhances the expression of MUC1 through the transcriptional regulation by HIF-1alpha in a human lung epithelial cell line. 19141292

2009