| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
BRCA2 DNA repair associated | 0.379 | 0.846 | 2.4E-25 |
|
disease | 1.000 | strong | 0.951 | 24 | 69 | 1994 | 2020 | ||||||||
|
BRCA1 DNA repair associated | 0.367 | 0.923 | 9.2E-29 |
|
disease | 1.000 | strong | 0.956 | 22 | 88 | 1992 | 2020 | ||||||||
|
partner and localizer of BRCA2 | 0.485 | 0.769 | 3.0E-19 |
|
disease | 0.800 | None | 0.970 | 3 | 1 | 2006 | 2020 | ||||||||
|
checkpoint kinase 2 | 0.460 | 0.808 | 1.2E-24 |
|
disease | 0.800 | None | 0.963 | 3 | 1 | 2001 | 2019 | ||||||||
|
RAD51 recombinase | 0.447 | 0.846 | 2.7E-02 |
|
disease | 0.600 | None | 0.957 | 2 | 1 | 1997 | 2019 | ||||||||
|
abraxas 1, BRCA1 A complex subunit | 0.760 | 0.269 | 5.1E-07 |
|
disease | 0.350 | None | 0.714 | 2 | 1 | 2009 | 2019 | ||||||||
|
BRCA1 interacting protein C-terminal helicase 1 | 0.507 | 0.731 | 6.2E-17 |
|
disease | 0.800 | None | 0.951 | 2 | 2 | 2001 | 2020 | ||||||||
|
AKT serine/threonine kinase 1 | 0.311 | 0.962 | 0.98 |
|
disease | 0.700 | limited | 0.993 | 1 | 1 | 1999 | 2020 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | 0.292 | 0.923 | 1.00 |
|
disease | 1.000 | None | 0.985 | 1 | 6 | 2001 | 2020 | ||||||||
|
nibrin | 0.467 | 0.808 | 2.2E-16 |
|
disease | 0.500 | None | 0.894 | 1 | 1 | 2002 | 2019 | ||||||||
|
gasdermin B | 0.670 | 0.500 | 3.3E-07 |
|
disease | 0.320 | None | 1.000 | 0 | 0 | 2014 | 2019 | ||||||||
|
protein tyrosine phosphatase non-receptor type 14 | 0.638 | 0.615 | 0.22 |
|
disease | 0.310 | None | 1.000 | 0 | 1 | 2015 | 2015 | ||||||||
|
ectopic P-granules autophagy protein 5 homolog | 0.623 | 0.769 | 1.4E-13 |
|
disease | 0.310 | None | 1.000 | 0 | 2 | 2007 | 2007 | ||||||||
|
MAGE family member E1 | 0.736 | 0.423 | 0.97 |
|
disease | 0.300 | None | 0 | 0 | |||||||||||
|
PDZ domain containing 4 | 0.890 | 0.154 | 0.85 |
|
disease | 0.300 | None | 0 | 1 | |||||||||||
|
protein tyrosine phosphatase receptor type C | 0.435 | 0.808 | 1.00 |
|
disease | 0.340 | None | 1.000 | 0 | 0 | 2012 | 2019 | ||||||||
|
BRCA1 associated RING domain 1 | 0.597 | 0.538 | 1.4E-24 |
|
disease | 1.000 | limited | 0.896 | 0 | 1 | 1996 | 2020 | ||||||||
|
DEAH-box helicase 32 (putative) | 0.760 | 0.269 | 1.6E-09 |
|
disease | 0.310 | None | 1.000 | 0 | 0 | 2017 | 2017 | ||||||||
|
WAP four-disulfide core domain 1 | 0.743 | 0.346 | 3.5E-11 |
|
disease | 0.300 | None | 0 | 1 | |||||||||||
|
oligosaccharyltransferase complex non-catalytic subunit | 1.000 | 0.077 | 1.8E-02 |
|
disease | 0.300 | None | 0 | 0 | |||||||||||
|
Rac family small GTPase 2 | 0.556 | 0.731 | 0.97 |
|
disease | 0.310 | None | 1.000 | 0 | 0 | 2018 | 2018 | ||||||||
|
nucleoporin 133 | 0.678 | 0.577 | 9.3E-05 |
|
disease | 0.300 | None | 0 | 0 | |||||||||||
|
leucine rich repeat containing 7 | 0.722 | 0.462 | 1.00 |
|
disease | 0.300 | None | 0 | 0 | |||||||||||
|
KIAA1324 | 0.751 | 0.192 | 7.0E-13 |
|
disease | 0.300 | None | 0 | 0 | |||||||||||
|
AT-rich interaction domain 1B | 0.503 | 0.846 | 1.00 |
|
disease | 0.500 | None | 0 | 0 |