| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
tumor protein p53 | 0.236 | 0.962 | 0.53 |
|
group | 0.170 | None | 1.000 | 365 | 201 | 1989 | 2018 | ||||||||
|
cyclin dependent kinase inhibitor 2A | 0.300 | 0.885 | 0.39 |
|
group | 0.110 | None | 1.000 | 135 | 49 | 1994 | 2017 | ||||||||
|
phosphatase and tensin homolog | 0.305 | 0.923 | 0.26 |
|
group | 0.160 | None | 1.000 | 148 | 183 | 1997 | 2018 | ||||||||
|
BRCA1 DNA repair associated | 0.367 | 0.923 | 9.2E-29 |
|
group | 0.150 | None | 1.000 | 744 | 705 | 1975 | 2019 | ||||||||
|
APC regulator of WNT signaling pathway | 0.373 | 0.962 | 1.00 |
|
group | 0.110 | None | 1.000 | 159 | 257 | 1991 | 2017 | ||||||||
|
ATM serine/threonine kinase | 0.374 | 0.885 | 5.6E-47 |
|
group | 0.100 | None | 1.000 | 233 | 561 | 1989 | 2018 | ||||||||
|
BRCA2 DNA repair associated | 0.379 | 0.846 | 2.4E-25 |
|
group | 0.130 | None | 1.000 | 701 | 1021 | 1996 | 2019 | ||||||||
|
ret proto-oncogene | 0.392 | 0.885 | 1.00 |
|
group | 0.200 | None | 1.000 | 92 | 13 | 1992 | 2018 | ||||||||
|
patched 1 | 0.398 | 0.885 | 1.00 |
|
group | 0.100 | None | 1.000 | 11 | 44 | 1997 | 2014 | ||||||||
|
mutL homolog 1 | 0.399 | 0.808 | 3.4E-05 |
|
group | 0.150 | None | 1.000 | 298 | 189 | 1978 | 2018 | ||||||||
|
cadherin 1 | 0.401 | 0.808 | 0.15 |
|
group | 0.130 | None | 1.000 | 66 | 87 | 1994 | 2019 | ||||||||
|
SMAD family member 4 | 0.401 | 0.808 | 1.00 |
|
group | 0.100 | None | 1.000 | 35 | 35 | 1998 | 2017 | ||||||||
|
mutS homolog 2 | 0.406 | 0.808 | 0.90 |
|
group | 0.130 | None | 1.000 | 320 | 309 | 1990 | 2018 | ||||||||
|
cyclin dependent kinase 4 | 0.412 | 0.808 | 6.3E-02 |
|
group | 0.100 | None | 0 | 1 | |||||||||||
|
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 | 0.434 | 0.846 | 1.00 |
|
group | 0.100 | None | 1.000 | 1 | 1 | 2010 | 2010 | ||||||||
|
serine/threonine kinase 11 | 0.435 | 0.808 | 0.99 |
|
group | 0.120 | None | 1.000 | 39 | 64 | 1992 | 2018 | ||||||||
|
homeostatic iron regulator | 0.436 | 0.846 | 2.6E-08 |
|
group | 0.100 | None | 0 | 1 | |||||||||||
|
TSC complex subunit 2 | 0.439 | 0.808 | 1.00 |
|
group | 0.110 | None | 1.000 | 30 | 29 | 1994 | 2017 | ||||||||
|
neurofibromin 1 | 0.440 | 0.885 | 0.90 |
|
group | 0.100 | None | 1.000 | 139 | 215 | 1990 | 2018 | ||||||||
|
von Hippel-Lindau tumor suppressor | 0.443 | 0.846 | 8.0E-02 |
|
group | 0.180 | None | 1.000 | 165 | 59 | 1994 | 2017 | ||||||||
|
RB transcriptional corepressor 1 | 0.444 | 0.885 | 1.00 |
|
group | 0.100 | None | 1.000 | 71 | 103 | 1989 | 2018 | ||||||||
|
dicer 1, ribonuclease III | 0.446 | 0.846 | 1.00 |
|
group | 0.120 | None | 1.000 | 12 | 90 | 2009 | 2016 | ||||||||
|
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 | 0.450 | 0.885 | 1.00 |
|
group | 0.100 | None | 1.000 | 2 | 4 | 2011 | 2014 | ||||||||
|
BRCA1 associated protein 1 | 0.454 | 0.731 | 0.99 |
|
group | 0.180 | None | 1.000 | 11 | 23 | 2011 | 2019 | ||||||||
|
checkpoint kinase 2 | 0.460 | 0.808 | 1.2E-24 |
|
group | 0.100 | None | 1.000 | 106 | 133 | 1999 | 2019 |