Source: MGD

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 10673
Gene Symbol: TNFSF13B
TNFSF13B
CUI: C0086981
Disease: Sicca Syndrome
Sicca Syndrome
0.220 Biomarker MGD

Entrez Id: 6768
Gene Symbol: ST14
ST14
CUI: C0086981
Disease: Sicca Syndrome
Sicca Syndrome
0.200 Biomarker MGD

Entrez Id: 6097
Gene Symbol: RORC
RORC
CUI: C0086981
Disease: Sicca Syndrome
Sicca Syndrome
0.200 Biomarker MGD

Entrez Id: 355
Gene Symbol: FAS
FAS
CUI: C0086981
Disease: Sicca Syndrome
Sicca Syndrome
0.200 Biomarker MGD Spontaneous murine lupus-like syndromes. Clinical and immunopathological manifestations in several strains. 309911

1978

Entrez Id: 355
Gene Symbol: FAS
FAS
CUI: C0086981
Disease: Sicca Syndrome
Sicca Syndrome
0.200 Biomarker MGD Distribution of lymphocytes identified by surface markers in murine strains with systemic lupus erythematosus-like syndromes. 762500

1979

Entrez Id: 355
Gene Symbol: FAS
FAS
CUI: C0086981
Disease: Sicca Syndrome
Sicca Syndrome
0.200 Biomarker MGD MRL/MP-lpr/lpr mouse as a model of immune-induced sensorineural hearing loss. 1416659

1992

Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
CUI: C0086981
Disease: Sicca Syndrome
Sicca Syndrome
0.210 Biomarker MGD Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease. 1436033

1992

Entrez Id: 355
Gene Symbol: FAS
FAS
CUI: C0086981
Disease: Sicca Syndrome
Sicca Syndrome
0.200 Biomarker MGD Lacrimal and salivary gland inflammation in the C3H/Ipr autoimmune strain mouse: a potential mode for Sjögren's syndrome. 1565490

1992

Entrez Id: 355
Gene Symbol: FAS
FAS
CUI: C0086981
Disease: Sicca Syndrome
Sicca Syndrome
0.200 Biomarker MGD Phenotypic, functional, and molecular genetic comparisons of the abnormal lymphoid cells of C3H-lpr/lpr and C3H-gld/gld mice. 3009614

1986

Entrez Id: 355
Gene Symbol: FAS
FAS
CUI: C0086981
Disease: Sicca Syndrome
Sicca Syndrome
0.200 Biomarker MGD Splenic immunoglobulin-secreting cells and their regulation in autoimmune mice. 6444324

1980

Entrez Id: 355
Gene Symbol: FAS
FAS
CUI: C0086981
Disease: Sicca Syndrome
Sicca Syndrome
0.200 Biomarker MGD Induction of various autoantibodies by mutant gene lpr in several strains of mice. 6609979

1984

Entrez Id: 355
Gene Symbol: FAS
FAS
CUI: C0086981
Disease: Sicca Syndrome
Sicca Syndrome
0.200 Biomarker MGD Dissociation of severe lupus-like disease from polyclonal B cell activation and IL 2 deficiency in C3H-lpr/lpr mice. 6610701

1984

Entrez Id: 355
Gene Symbol: FAS
FAS
CUI: C0086981
Disease: Sicca Syndrome
Sicca Syndrome
0.200 Biomarker MGD Deficient interleukin 2 activity in MRL/Mp and C57BL/6J mice bearing the lpr gene. 6975351

1981

Entrez Id: 355
Gene Symbol: FAS
FAS
CUI: C0086981
Disease: Sicca Syndrome
Sicca Syndrome
0.200 Biomarker MGD Reduced cell-cell communication in a spontaneous murine model of autoimmune thyroid disease. 7628400

1995

Entrez Id: 355
Gene Symbol: FAS
FAS
CUI: C0086981
Disease: Sicca Syndrome
Sicca Syndrome
0.200 Biomarker MGD Transfer of Sjögren's syndrome-like autoimmune lesions into SCID mice and prevention of lesions by anti-CD4 and anti-T cell receptor antibody treatment. 7957574

1994

Entrez Id: 355
Gene Symbol: FAS
FAS
CUI: C0086981
Disease: Sicca Syndrome
Sicca Syndrome
0.200 Biomarker MGD Comparative influence of steroid hormones and immunosuppressive agents on autoimmune expression in lacrimal glands of a female mouse model of Sjögren's syndrome. 8163351

1994

Entrez Id: 355
Gene Symbol: FAS
FAS
CUI: C0086981
Disease: Sicca Syndrome
Sicca Syndrome
0.200 Biomarker MGD Cognitive and neurologic deficits in the MRL/lpr mouse: a clinicopathologic study. 8496852

1993

Entrez Id: 9020
Gene Symbol: MAP3K14
MAP3K14
CUI: C0086981
Disease: Sicca Syndrome
Sicca Syndrome
0.200 Biomarker MGD T-cell receptor repertoire of infiltrating T cells in lachrymal glands, salivary glands and kidneys from alymphoplasia (aly) mutant mice: a new model for Sjögren's syndrome. 9010048

1996

Entrez Id: 1588
Gene Symbol: CYP19A1
CYP19A1
CUI: C0086981
Disease: Sicca Syndrome
Sicca Syndrome
0.200 Biomarker MGD Characterization of mice deficient in aromatase (ArKO) because of targeted disruption of the cyp19 gene. 9618522

1998

Entrez Id: 9020
Gene Symbol: MAP3K14
MAP3K14
CUI: C0086981
Disease: Sicca Syndrome
Sicca Syndrome
0.200 Biomarker MGD aly/aly mice: a unique model of biliary disease. 9620319

1998

Entrez Id: 1588
Gene Symbol: CYP19A1
CYP19A1
CUI: C0086981
Disease: Sicca Syndrome
Sicca Syndrome
0.200 Biomarker MGD Disruption of sexual behavior in male aromatase-deficient mice lacking exons 1 and 2 of the cyp19 gene. 9826549

1998

Entrez Id: 1588
Gene Symbol: CYP19A1
CYP19A1
CUI: C0086981
Disease: Sicca Syndrome
Sicca Syndrome
0.200 Biomarker MGD Impairment of spermatogenesis in mice lacking a functional aromatase (cyp 19) gene. 10393934

1999

Entrez Id: 355
Gene Symbol: FAS
FAS
CUI: C0086981
Disease: Sicca Syndrome
Sicca Syndrome
0.200 Biomarker MGD Another cell death induction system: TNF-alpha acts as a ligand for Fas in vaginal cells. 10453074

1999

Entrez Id: 1588
Gene Symbol: CYP19A1
CYP19A1
CUI: C0086981
Disease: Sicca Syndrome
Sicca Syndrome
0.200 Biomarker MGD An age-related ovarian phenotype in mice with targeted disruption of the Cyp 19 (aromatase) gene. 10875266

2000

Entrez Id: 9020
Gene Symbol: MAP3K14
MAP3K14
CUI: C0086981
Disease: Sicca Syndrome
Sicca Syndrome
0.200 Biomarker MGD Mammary glands of Aly mice: developmental changes and lactation-related expression of specific proteins, alpha-casein, GLyCAM-1 and MAdCAM-1. 10910194

2000