Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C2316810
Disease: Chronic kidney disease stage 5
Chronic kidney disease stage 5
0.210 Biomarker RGD Down-regulation of intestinal drug transporters in chronic renal failure in rats. 17135344

2007

Entrez Id: 1244
Gene Symbol: ABCC2
ABCC2
CUI: C2316810
Disease: Chronic kidney disease stage 5
Chronic kidney disease stage 5
0.200 Biomarker RGD Down-regulation of intestinal drug transporters in chronic renal failure in rats. 17135344

2007

Entrez Id: 8714
Gene Symbol: ABCC3
ABCC3
CUI: C2316810
Disease: Chronic kidney disease stage 5
Chronic kidney disease stage 5
0.200 Biomarker RGD Down-regulation of intestinal drug transporters in chronic renal failure in rats. 17135344

2007

Entrez Id: 38
Gene Symbol: ACAT1
ACAT1
CUI: C2316810
Disease: Chronic kidney disease stage 5
Chronic kidney disease stage 5
0.200 Biomarker RGD Niacin improves renal lipid metabolism and slows progression in chronic kidney disease. 19878707

2010

Entrez Id: 1636
Gene Symbol: ACE
ACE
CUI: C2316810
Disease: Chronic kidney disease stage 5
Chronic kidney disease stage 5
0.300 Therapeutic RGD Carbonic adsorbent AST-120 retards progression of renal failure by additive effect with ACEI and protein restriction diet. 14586729

2003

Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ
CUI: C2316810
Disease: Chronic kidney disease stage 5
Chronic kidney disease stage 5
0.300 Biomarker RGD Changes of adiponectin and its receptors in rats following chronic renal failure. 24028144

2014

Entrez Id: 51094
Gene Symbol: ADIPOR1
ADIPOR1
CUI: C2316810
Disease: Chronic kidney disease stage 5
Chronic kidney disease stage 5
0.230 Biomarker RGD Changes of adiponectin and its receptors in rats following chronic renal failure. 24028144

2014

Entrez Id: 79602
Gene Symbol: ADIPOR2
ADIPOR2
CUI: C2316810
Disease: Chronic kidney disease stage 5
Chronic kidney disease stage 5
0.210 Biomarker RGD Changes of adiponectin and its receptors in rats following chronic renal failure. 24028144

2014

Entrez Id: 384
Gene Symbol: ARG2
ARG2
CUI: C2316810
Disease: Chronic kidney disease stage 5
Chronic kidney disease stage 5
0.200 Biomarker RGD Effect of chronic renal failure on arginase and argininosuccinate synthetase expression. 16809898

2006

Entrez Id: 596
Gene Symbol: BCL2
BCL2
CUI: C2316810
Disease: Chronic kidney disease stage 5
Chronic kidney disease stage 5
0.210 Therapeutic RGD Epoetin delta as an antifibrotic agent in the remnant kidney rat: a possible role for transforming growth factor beta and hepatocyte growth factor. 20424483

2010

Entrez Id: 8678
Gene Symbol: BECN1
BECN1
CUI: C2316810
Disease: Chronic kidney disease stage 5
Chronic kidney disease stage 5
0.200 Biomarker RGD Mitochondrial impairment in the five-sixth nephrectomy model of chronic renal failure: proteomic approach. 24090408

2013

Entrez Id: 632
Gene Symbol: BGLAP
BGLAP
CUI: C2316810
Disease: Chronic kidney disease stage 5
Chronic kidney disease stage 5
0.210 Biomarker RGD Role of dietary phosphorus and degree of uremia in the development of renal bone disease in rats. 17365904

2007

Entrez Id: 664
Gene Symbol: BNIP3
BNIP3
CUI: C2316810
Disease: Chronic kidney disease stage 5
Chronic kidney disease stage 5
0.200 Biomarker RGD Mitochondrial impairment in the five-sixth nephrectomy model of chronic renal failure: proteomic approach. 24090408

2013

Entrez Id: 729
Gene Symbol: C6
C6
CUI: C2316810
Disease: Chronic kidney disease stage 5
Chronic kidney disease stage 5
0.200 ModifyingMutation RGD C6 mediates chronic progression of tubulointerstitial damage in rats with remnant kidneys. 11912252

2002

Entrez Id: 847
Gene Symbol: CAT
CAT
CUI: C2316810
Disease: Chronic kidney disease stage 5
Chronic kidney disease stage 5
0.200 Biomarker RGD Contribution of impaired Nrf2-Keap1 pathway to oxidative stress and inflammation in chronic renal failure. 20007347

2010

Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C2316810
Disease: Chronic kidney disease stage 5
Chronic kidney disease stage 5
0.290 Biomarker RGD Expression of monocyte chemoattractant protein-1 in proximal tubular epithelial cells in a rat model of progressive kidney failure. 12080327

2002

Entrez Id: 6347
Gene Symbol: CCL2
CCL2
CUI: C2316810
Disease: Chronic kidney disease stage 5
Chronic kidney disease stage 5
0.290 Therapeutic RGD Effect of exercise on cardiac tissue oxidative and inflammatory mediators in chronic kidney disease. 18797164

2009

Entrez Id: 6352
Gene Symbol: CCL5
CCL5
CUI: C2316810
Disease: Chronic kidney disease stage 5
Chronic kidney disease stage 5
0.220 Biomarker RGD Role of FTY720 on M1 and M2 macrophages, lymphocytes, and chemokines in 5/6 nephrectomized rats. 19535570

2009

Entrez Id: 1234
Gene Symbol: CCR5
CCR5
CUI: C2316810
Disease: Chronic kidney disease stage 5
Chronic kidney disease stage 5
0.260 Biomarker RGD Role of FTY720 on M1 and M2 macrophages, lymphocytes, and chemokines in 5/6 nephrectomized rats. 19535570

2009

Entrez Id: 1535
Gene Symbol: CYBA
CYBA
CUI: C2316810
Disease: Chronic kidney disease stage 5
Chronic kidney disease stage 5
0.250 Biomarker RGD Niacin ameliorates oxidative stress, inflammation, proteinuria, and hypertension in rats with chronic renal failure. 19420110

2009

Entrez Id: 1536
Gene Symbol: CYBB
CYBB
CUI: C2316810
Disease: Chronic kidney disease stage 5
Chronic kidney disease stage 5
0.210 Biomarker RGD Iron and oxidative stress in renal insufficiency. 15550752

2005

Entrez Id: 1543
Gene Symbol: CYP1A1
CYP1A1
CUI: C2316810
Disease: Chronic kidney disease stage 5
Chronic kidney disease stage 5
0.200 Biomarker RGD Downregulation of intestinal cytochrome p450 in chronic renal failure. 12039987

2002

Entrez Id: 1644
Gene Symbol: DDC
DDC
CUI: C2316810
Disease: Chronic kidney disease stage 5
Chronic kidney disease stage 5
0.200 Biomarker RGD Renal dopaminergic system activity in rat remnant kidney up to twenty-six weeks after surgery. 19167406

2009

Entrez Id: 1812
Gene Symbol: DRD1
DRD1
CUI: C2316810
Disease: Chronic kidney disease stage 5
Chronic kidney disease stage 5
0.200 Therapeutic RGD Delivery of recombinant adeno-associated virus-mediated human tissue kallikrein for therapy of chronic renal failure in rats. 18402547

2008

Entrez Id: 1906
Gene Symbol: EDN1
EDN1
CUI: C2316810
Disease: Chronic kidney disease stage 5
Chronic kidney disease stage 5
0.240 Biomarker RGD Renal endothelin gene expression is increased in remnant kidney and correlates with disease progression. 8441230

1993