Source: PSYGENET

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2
Gene Symbol: A2M
A2M
CUI: C0011570
Disease: Mental Depression
Mental Depression
0.300 Biomarker PSYGENET CF heterozygotes shared the decrease of alpha 1-lipoprotein with the patients while exhibiting small but significant depressions of alpha 2-macroglobulin and IgG. 2432615

1987

Entrez Id: 2
Gene Symbol: A2M
A2M
CUI: C0011570
Disease: Mental Depression
Mental Depression
0.300 Biomarker PSYGENET In the present study we tested two polymorphisms in the alpha-2 macroglobulin gene, a 5 bp deletion at the 5' splice site of exon 18 and a G/A point mutation (V1000I) in exon 24, in a sample of 118 healthy, non demented controls and 238 consecutively recruited gerontopsychiatric patients, diagnosed as: Alzheimer's disease (N=88), mild cognitive impairment (N=32), subjective cognitive complaints (N=54) and depression/other psychiatric disorders (N=64). 11058789

2000

Entrez Id: 2
Gene Symbol: A2M
A2M
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.300 Biomarker PSYGENET Protein abnormalities in adult respiratory distress syndrome, tuberculosis, and cystic fibrosis sera. 2432615

1987

Entrez Id: 2
Gene Symbol: A2M
A2M
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.300 Biomarker PSYGENET In the present study we tested two polymorphisms in the alpha-2 macroglobulin gene, a 5 bp deletion at the 5' splice site of exon 18 and a G/A point mutation (V1000I) in exon 24, in a sample of 118 healthy, non demented controls and 238 consecutively recruited gerontopsychiatric patients, diagnosed as: Alzheimer's disease (N=88), mild cognitive impairment (N=32), subjective cognitive complaints (N=54) and depression/other psychiatric disorders (N=64). 11058789

2000

Entrez Id: 15
Gene Symbol: AANAT
AANAT
CUI: C0005587
Disease: Depression, Bipolar
Depression, Bipolar
0.300 Biomarker PSYGENET We assessed the contribution of AANAT gene variability to susceptibility to MD considering common and rare genetic variations through a sequential sequencing and single nucleotide polymorphism (SNP)-based genotyping approach in a sample of 445 unrelated patients with MD (257 unipolar MD, 188 bipolar depression) and 440 community-based screened control subjects. 20459461

2010

Entrez Id: 15
Gene Symbol: AANAT
AANAT
CUI: C0011570
Disease: Mental Depression
Mental Depression
0.300 Biomarker PSYGENET The mutant, AANAT knocked down C57BL/6J mice displayed significantly longer times of immobility ("depression"). 11316327

2001

Entrez Id: 15
Gene Symbol: AANAT
AANAT
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.300 Biomarker PSYGENET The mutant, AANAT knocked down C57BL/6J mice displayed significantly longer times of immobility ("depression"). 11316327

2001

Entrez Id: 19
Gene Symbol: ABCA1
ABCA1
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.310 Biomarker PSYGENET Our data suggest a male-specific association of the 1587 K allele of ABCA1 with susceptibility to schizophrenia and smaller gray matter volume in schizophrenia. 21839797

2011

Entrez Id: 154664
Gene Symbol: ABCA13
ABCA13
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.420 Biomarker PSYGENET After the initial discovery of its disruption by a chromosome abnormality in a person with schizophrenia, we resequenced ABCA13 exons in 100 cases with schizophrenia and 100 controls. 19944402

2009

Entrez Id: 154664
Gene Symbol: ABCA13
ABCA13
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.310 Biomarker PSYGENET We report evidence that the lipid transporter gene ABCA13 is a susceptibility factor for both schizophrenia and bipolar disorder. 19944402

2009

Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.500 Biomarker PSYGENET The aim of this study was to determine the association between MDR1 gene polymorphisms and clinical characteristics in patients with schizophrenia. 24918524

2014

Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.500 Biomarker PSYGENET Genetic variation in ABCB1 may be associated with P300 amplitude in patients with schizophrenia. 22910404

2012

Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.500 Biomarker PSYGENET Effects of genetic polymorphisms of CYP2D6, CYP3A5, and ABCB1 on the steady-state plasma concentrations of aripiprazole and its active metabolite, dehydroaripiprazole, in Japanese patients with schizophrenia. 24682161

2014

Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.500 Biomarker PSYGENET Impact of the ABCB1 gene polymorphism on plasma 9-hydroxyrisperidone and active moiety levels in Japanese patients with schizophrenia. 23609388

2013

Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0011570
Disease: Mental Depression
Mental Depression
0.400 Biomarker PSYGENET The present study suggests that the C3435T polymorphism of the MDR1 gene affects the formation of a depression-prone personality trait in Japanese females. 24577069

2014

Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0011570
Disease: Mental Depression
Mental Depression
0.400 Biomarker PSYGENET Impact of ABCB1 variants on neutrophil depression: a pharmacogenomic study of paclitaxel in 92 women with ovarian cancer. 21955855

2012

Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0011570
Disease: Mental Depression
Mental Depression
0.400 Biomarker PSYGENET Results suggest that antidepressant treatment of depression can be optimized by the clinical application of ABCB1 genotyping. 23880209

2014

Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0011570
Disease: Mental Depression
Mental Depression
0.400 Biomarker PSYGENET Silencing clusterin gene transcription on effects of multidrug resistance reversing of human hepatoma HepG2/ADM cells. 25600802

2015

Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0011570
Disease: Mental Depression
Mental Depression
0.400 Biomarker PSYGENET Our findings suggest that single nucleotide polymorphisms in the ABCB1 gene may be indicators of the severity of depression and of the likely S-CIT treatment remission response in MDD. 20859246

2011

Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.400 Biomarker PSYGENET The present study suggests that the C3435T polymorphism of the MDR1 gene affects the formation of a depression-prone personality trait in Japanese females. 24577069

2014

Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.400 Biomarker PSYGENET Silencing clusterin gene transcription on effects of multidrug resistance reversing of human hepatoma HepG2/ADM cells. 25600802

2015

Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.400 Biomarker PSYGENET Our findings suggest that single nucleotide polymorphisms in the ABCB1 gene may be indicators of the severity of depression and of the likely S-CIT treatment remission response in MDD. 20859246

2011

Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.400 Biomarker PSYGENET Impact of ABCB1 variants on neutrophil depression: a pharmacogenomic study of paclitaxel in 92 women with ovarian cancer. 21955855

2012

Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0011581
Disease: Depressive disorder
Depressive disorder
0.400 Biomarker PSYGENET Results suggest that antidepressant treatment of depression can be optimized by the clinical application of ABCB1 genotyping. 23880209

2014

Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression
0.400 Biomarker PSYGENET In this study we investigated 36 single nucleotide polymorphisms within 10 genes previously associated with major depression and bipolar disorder, as well as with the response to their treatment (ABCB1, ABCB4, TAP2, CLOCK, CPLX1, CPLX2, SYN2, NRG1, 5HTR1A and GPRIN2). 23273899

2013