Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1588
Gene Symbol: CYP19A1
CYP19A1
CUI: C0086981
Disease: Sicca Syndrome
Sicca Syndrome
0.200 Biomarker MGD An age-related ovarian phenotype in mice with targeted disruption of the Cyp 19 (aromatase) gene. 10875266

2000

Entrez Id: 1588
Gene Symbol: CYP19A1
CYP19A1
CUI: C0086981
Disease: Sicca Syndrome
Sicca Syndrome
0.200 Biomarker MGD Disruption of sexual behavior in male aromatase-deficient mice lacking exons 1 and 2 of the cyp19 gene. 9826549

1998

Entrez Id: 1588
Gene Symbol: CYP19A1
CYP19A1
CUI: C0086981
Disease: Sicca Syndrome
Sicca Syndrome
0.200 Biomarker MGD Characterization of mice deficient in aromatase (ArKO) because of targeted disruption of the cyp19 gene. 9618522

1998

Entrez Id: 1588
Gene Symbol: CYP19A1
CYP19A1
CUI: C0086981
Disease: Sicca Syndrome
Sicca Syndrome
0.200 Biomarker MGD Aromatase-deficient mice spontaneously develop a lymphoproliferative autoimmune disease resembling Sjogren's syndrome. 15314222

2004

Entrez Id: 1588
Gene Symbol: CYP19A1
CYP19A1
CUI: C0086981
Disease: Sicca Syndrome
Sicca Syndrome
0.200 Biomarker MGD Aromatase controls Sjögren syndrome-like lesions through monocyte chemotactic protein-1 in target organ and adipose tissue-associated macrophages. 25447050

2015

Entrez Id: 1588
Gene Symbol: CYP19A1
CYP19A1
CUI: C0086981
Disease: Sicca Syndrome
Sicca Syndrome
0.200 Biomarker MGD Impairment of spermatogenesis in mice lacking a functional aromatase (cyp 19) gene. 10393934

1999

Entrez Id: 1588
Gene Symbol: CYP19A1
CYP19A1
CUI: C0086981
Disease: Sicca Syndrome
Sicca Syndrome
0.200 Biomarker MGD Elevated androgens and prolactin in aromatase-deficient mice cause enlargement, but not malignancy, of the prostate gland. 11356695

2001

Entrez Id: 1588
Gene Symbol: CYP19A1
CYP19A1
CUI: C0086981
Disease: Sicca Syndrome
Sicca Syndrome
0.200 Biomarker MGD Aromatase-deficient (ArKO) mice have reduced blood pressure and baroreflex sensitivity. 15178650

2004