Source: RGD

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3569
Gene Symbol: IL6
IL6
CUI: C0004096
Disease: Asthma
Asthma
0.600 Biomarker RGD

Entrez Id: 10891
Gene Symbol: PPARGC1A
PPARGC1A
CUI: C0008312
Disease: Primary biliary cirrhosis
Primary biliary cirrhosis
0.220 Biomarker RGD

Entrez Id: 2660
Gene Symbol: MSTN
MSTN
CUI: C0041948
Disease: Uremia
Uremia
0.210 Biomarker RGD

Entrez Id: 10891
Gene Symbol: PPARGC1A
PPARGC1A
CUI: C0023892
Disease: Biliary cirrhosis
Biliary cirrhosis
0.200 Biomarker RGD

Entrez Id: 6372
Gene Symbol: CXCL6
CXCL6
CUI: C0033581
Disease: prostatitis
prostatitis
0.200 Biomarker RGD

Entrez Id: 4583
Gene Symbol: MUC2
MUC2
CUI: C0520459
Disease: Necrotizing Enterocolitis
Necrotizing Enterocolitis
0.200 Biomarker RGD

Entrez Id: 1728
Gene Symbol: NQO1
NQO1
Chemical and Drug Induced Liver Injury
0.200 Therapeutic RGD 28522909

2017

Entrez Id: 3897
Gene Symbol: L1CAM
L1CAM
CUI: C0003469
Disease: Anxiety Disorders
Anxiety Disorders
0.200 Biomarker RGD """Juvenile stress"" alters maturation-related changes in expression of the neural cell adhesion molecule L1 in the limbic system: relevance for stress-related psychopathologies." 19746433

2010

Entrez Id: 4582
Gene Symbol: MUC1
MUC1
CUI: C0280725
Disease: Adult Cholangiocarcinoma
Adult Cholangiocarcinoma
0.200 Biomarker RGD "A novel ""patient-like"" model of cholangiocarcinoma progression based on bile duct inoculation of tumorigenic rat cholangiocyte cell lines." 18081149

2008

Entrez Id: 718
Gene Symbol: C3
C3
CUI: C0242488
Disease: Acute Lung Injury
Acute Lung Injury
0.200 Therapeutic RGD "Beneficial effect of the polysaccharides from Bupleurum smithii var. parvifolium on ""two-hit"" acute lung injury in rats." 22763771

2012

Entrez Id: 4322
Gene Symbol: MMP13
MMP13
CUI: C0410606
Disease: Cervical Disc Degenerative Disorder
Cervical Disc Degenerative Disorder
0.200 Therapeutic RGD "Herb formula ""Fufangqishe-Pill"" prevents upright posture-induced intervertebral disc degeneration at the lumbar in rats." 20472983

2010

Entrez Id: 4314
Gene Symbol: MMP3
MMP3
CUI: C0410606
Disease: Cervical Disc Degenerative Disorder
Cervical Disc Degenerative Disorder
0.200 Therapeutic RGD "Herb formula ""Fufangqishe-Pill"" prevents upright posture-induced intervertebral disc degeneration at the lumbar in rats." 20472983

2010

Entrez Id: 2535
Gene Symbol: FZD2
FZD2
CUI: C0149721
Disease: Left Ventricular Hypertrophy
Left Ventricular Hypertrophy
0.200 Biomarker RGD "Increased expression of a homologue of drosophila tissue polarity gene ""frizzled"" in left ventricular hypertrophy in the rat, as identified by subtractive hybridization." 8762054

1996

Entrez Id: 5972
Gene Symbol: REN
REN
CUI: C0011881
Disease: Diabetic Nephropathy
Diabetic Nephropathy
0.300 Biomarker RGD "Inhibition of diabetic nephropathy by a decoy peptide corresponding to the ""handle"" region for nonproteolytic activation of prorenin." 15489960

2004

Entrez Id: 3976
Gene Symbol: LIF
LIF
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia
0.200 Biomarker RGD "TGFbeta1 stimulates the over-production of white matter astrocytes from precursors of the ""brain marrow"" in a rodent model of neonatal encephalopathy." 20221422

2010

Entrez Id: 57555
Gene Symbol: NLGN2
NLGN2
CUI: C0020429
Disease: Hyperalgesia
Hyperalgesia
0.200 Biomarker RGD "Unexpected association of the ""inhibitory"" neuroligin 2 with excitatory PSD95 in neuropathic pain." 23891900

2013

Entrez Id: 3082
Gene Symbol: HGF
HGF
CUI: C0280725
Disease: Adult Cholangiocarcinoma
Adult Cholangiocarcinoma
0.200 Biomarker RGD "Unique epithelial cell production of hepatocyte growth factor/scatter factor by putative precancerous intestinal metaplasias and associated ""intestinal-type"" biliary cancer chemically induced in rat liver." 10827151

2000

Entrez Id: 596
Gene Symbol: BCL2
BCL2
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
0.600 Therapeutic RGD "Xiusanzhen" can regulate the expression of hippocampal Bcl-2 and Bax proteins in AD rats, which may contribute to its clinical effect in relieving AD, and the therapeutic effect depends on the integrity of the olfactory nerve pathway. 21585051

2011

Entrez Id: 581
Gene Symbol: BAX
BAX
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
0.520 Therapeutic RGD "Xiusanzhen" can regulate the expression of hippocampal Bcl-2 and Bax proteins in AD rats, which may contribute to its clinical effect in relieving AD, and the therapeutic effect depends on the integrity of the olfactory nerve pathway. 21585051

2011

Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C0009324
Disease: Ulcerative Colitis
Ulcerative Colitis
0.600 Biomarker RGD "[Exploration of the theory of ""Fei and Dachang being interior-exteriorly related"" from observing changes of inflammatory cytokines and oxygen free radicals in the lung tissue of ulcerative colitis rats]." 24812904

2014

Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C0009324
Disease: Ulcerative Colitis
Ulcerative Colitis
0.600 Biomarker RGD "[Exploration of the theory of ""Fei and Dachang being interior-exteriorly related"" from observing changes of inflammatory cytokines and oxygen free radicals in the lung tissue of ulcerative colitis rats]." 24812904

2014

Entrez Id: 3553
Gene Symbol: IL1B
IL1B
Chronic left-sided ulcerative colitis
0.200 Biomarker RGD "[Exploration of the theory of ""Fei and Dachang being interior-exteriorly related"" from observing changes of inflammatory cytokines and oxygen free radicals in the lung tissue of ulcerative colitis rats]." 24812904

2014

Entrez Id: 7124
Gene Symbol: TNF
TNF
Chronic left-sided ulcerative colitis
0.200 Biomarker RGD "[Exploration of the theory of ""Fei and Dachang being interior-exteriorly related"" from observing changes of inflammatory cytokines and oxygen free radicals in the lung tissue of ulcerative colitis rats]." 24812904

2014

Entrez Id: 156
Gene Symbol: GRK2
GRK2
CUI: C0018801
Disease: Heart failure
Heart failure
0.600 Therapeutic RGD (-)-Epigallocatechin-3-gallate, the major green tea catechin, regulates the desensitization of β1 adrenoceptor via GRK2 in experimental heart failure. 29247373

2018

Entrez Id: 156
Gene Symbol: GRK2
GRK2
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure
0.600 Therapeutic RGD (-)-Epigallocatechin-3-gallate, the major green tea catechin, regulates the desensitization of β1 adrenoceptor via GRK2 in experimental heart failure. 29247373

2018