Source: CTD_human

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1
Gene Symbol: A1BG
A1BG
CUI: C0019209
Disease: Hepatomegaly
Hepatomegaly 		0.300 Biomarker CTD_human Discriminating between adaptive and carcinogenic liver hypertrophy in rat studies using logistic ridge regression analysis of toxicogenomic data: The mode of action and predictive models. 28108177

2017
Entrez Id: 1
Gene Symbol: A1BG
A1BG
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.300 Biomarker CTD_human Effects of olanzapine on serum protein phosphorylation patterns in patients with schizophrenia. 25821032

2015
Entrez Id: 2
Gene Symbol: A2M
A2M
CUI: C0027726
Disease: Nephrotic Syndrome
Nephrotic Syndrome 		0.510 Biomarker CTD_human We studied plasma antithrombin III (AT-III), alpha 1-PI, alpha 2-antiplasmin (alpha 2-A), alpha 2-macroglobulin (alpha 2-M) activity, and some blood coagulation and fibrinolysis tests in children with frequently relapsing prednisone-responsive NS. 11304663

2001
Entrez Id: 2
Gene Symbol: A2M
A2M
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.510 Biomarker CTD_human Distinctive immunohistochemical staining for alpha(2)M could be consistently demonstrated in GST-P-negative HAF, HCA, and HCC induced not only by peroxisome proliferators but also N-nitrosodiethylamine alone. 15509519

2004
Entrez Id: 2
Gene Symbol: A2M
A2M
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		0.500 Biomarker CTD_human Genetic association of an alpha2-macroglobulin (Val1000lle) polymorphism and Alzheimer's disease. 9811940

1998
Entrez Id: 2
Gene Symbol: A2M
A2M
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		0.500 Biomarker CTD_human Alpha-2 macroglobulin is genetically associated with Alzheimer disease. 9697696

1998
Entrez Id: 2
Gene Symbol: A2M
A2M
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		0.500 Biomarker CTD_human The presence of MPO-G/G and A2M-Val/Val genotypes synergistically increased the risk of AD (OR, 25.5; 95% CI, 4.65-139.75). 15023809

2004
Entrez Id: 2
Gene Symbol: A2M
A2M
CUI: C0206669
Disease: Hepatocellular Adenoma
Hepatocellular Adenoma 		0.500 Biomarker CTD_human Distinctive immunohistochemical staining for alpha(2)M could be consistently demonstrated in GST-P-negative HAF, HCA, and HCC induced not only by peroxisome proliferators but also N-nitrosodiethylamine alone. 15509519

2004
Entrez Id: 2
Gene Symbol: A2M
A2M
CUI: C0494463
Disease: Alzheimer Disease, Late Onset
Alzheimer Disease, Late Onset 		0.370 Biomarker CTD_human Alpha-2 macroglobulin is genetically associated with Alzheimer disease. 9697696

1998
Entrez Id: 2
Gene Symbol: A2M
A2M
CUI: C0494463
Disease: Alzheimer Disease, Late Onset
Alzheimer Disease, Late Onset 		0.370 Biomarker CTD_human Genetic association of an alpha2-macroglobulin (Val1000lle) polymorphism and Alzheimer's disease. 9811940

1998
Entrez Id: 2
Gene Symbol: A2M
A2M
CUI: C0494463
Disease: Alzheimer Disease, Late Onset
Alzheimer Disease, Late Onset 		0.370 Biomarker CTD_human Increased risk for Alzheimer disease with the interaction of MPO and A2M polymorphisms. 15023809

2004
Entrez Id: 2
Gene Symbol: A2M
A2M
CUI: C0024115
Disease: Lung diseases
Lung diseases 		0.320 Biomarker CTD_human The patient is heterozygous for an alteration in the A2M gene; this may be responsible for his serum A2M deficiency and may be relevant to the early onset of pulmonary disease in his case. 2475424

1989
Entrez Id: 2
Gene Symbol: A2M
A2M
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon 		0.310 Biomarker CTD_human Global gene expression analysis of rat colon cancers induced by a food-borne carcinogen, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine. 15059925

2004
Entrez Id: 2
Gene Symbol: A2M
A2M
CUI: C0276496
Disease: Familial Alzheimer Disease (FAD)
Familial Alzheimer Disease (FAD) 		0.310 Biomarker CTD_human Increased risk for Alzheimer disease with the interaction of MPO and A2M polymorphisms. 15023809

2004
Entrez Id: 2
Gene Symbol: A2M
A2M
CUI: C0276496
Disease: Familial Alzheimer Disease (FAD)
Familial Alzheimer Disease (FAD) 		0.310 Biomarker CTD_human Genetic association of an alpha2-macroglobulin (Val1000lle) polymorphism and Alzheimer's disease. 9811940

1998
Entrez Id: 2
Gene Symbol: A2M
A2M
CUI: C0276496
Disease: Familial Alzheimer Disease (FAD)
Familial Alzheimer Disease (FAD) 		0.310 Biomarker CTD_human Alpha-2 macroglobulin is genetically associated with Alzheimer disease. 9697696

1998
Entrez Id: 2
Gene Symbol: A2M
A2M
CUI: C3279661
Disease: alpha-2-Macroglobulin Deficiency
alpha-2-Macroglobulin Deficiency 		0.310 Biomarker CTD_human

Entrez Id: 2
Gene Symbol: A2M
A2M
CUI: C0009375
Disease: Colonic Neoplasms
Colonic Neoplasms 		0.300 Biomarker CTD_human Global gene expression analysis of rat colon cancers induced by a food-borne carcinogen, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine. 15059925

2004
Entrez Id: 2
Gene Symbol: A2M
A2M
CUI: C0011265
Disease: Presenile dementia
Presenile dementia 		0.300 Biomarker CTD_human Genetic association of an alpha2-macroglobulin (Val1000lle) polymorphism and Alzheimer's disease. 9811940

1998
Entrez Id: 2
Gene Symbol: A2M
A2M
CUI: C0011265
Disease: Presenile dementia
Presenile dementia 		0.300 Biomarker CTD_human Alpha-2 macroglobulin is genetically associated with Alzheimer disease. 9697696

1998
Entrez Id: 2
Gene Symbol: A2M
A2M
CUI: C0011265
Disease: Presenile dementia
Presenile dementia 		0.300 Biomarker CTD_human Increased risk for Alzheimer disease with the interaction of MPO and A2M polymorphisms. 15023809

2004
Entrez Id: 2
Gene Symbol: A2M
A2M
CUI: C0019202
Disease: Hepatolenticular Degeneration
Hepatolenticular Degeneration 		0.300 Biomarker CTD_human The early molecular processes underlying the neurological manifestations of an animal model of Wilson's disease. 23519153

2013
Entrez Id: 2
Gene Symbol: A2M
A2M
CUI: C0022660
Disease: Kidney Failure, Acute
Kidney Failure, Acute 		0.300 Biomarker CTD_human Repeat oral dose toxicity studies of melamine in rats and monkeys. 23052191

2013
Entrez Id: 2
Gene Symbol: A2M
A2M
CUI: C0023890
Disease: Liver Cirrhosis
Liver Cirrhosis 		0.300 Biomarker CTD_human Gene Expression Patterns Associated With Histopathology in Toxic Liver Fibrosis. 26396155

2016
Entrez Id: 2
Gene Symbol: A2M
A2M
CUI: C0023893
Disease: Liver Cirrhosis, Experimental
Liver Cirrhosis, Experimental 		0.300 Biomarker CTD_human Systems level analysis and identification of pathways and networks associated with liver fibrosis. 25380136

2014