×
Entrez Id: 3662
Gene Symbol: IRF4
IRF4
Infarction, Middle Cerebral Artery
0.200
Biomarker
RGD
Expression of interleukin-9 and its upstream stimulating factors in rats with ischemic stroke.
25652434 2015
×
Entrez Id: 2902
Gene Symbol: GRIN1
GRIN1
Infarction, Middle Cerebral Artery
0.200
Therapeutic
RGD
Long Noncoding RNA FosDT Promotes Ischemic Brain Injury by Interacting with REST-Associated Chromatin-Modifying Proteins.
26674869 2015
×
Entrez Id: 4137
Gene Symbol: MAPT
MAPT
Infarction, Middle Cerebral Artery
0.200
Therapeutic
RGD
Overactivation of NR2B-containing NMDA receptors through entorhinal-hippocampal connection initiates accumulation of hyperphosphorylated tau in rat hippocampus after transient middle cerebral artery occlusion.
25903928 2015
×
Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1
Infarction, Middle Cerebral Artery
0.200
Therapeutic
RGD
Bicyclol upregulates transcription factor Nrf2, HO-1 expression and protects rat brains against focal ischemia.
24252362 2014
×
Entrez Id: 6833
Gene Symbol: ABCC8
ABCC8
Infarction, Middle Cerebral Artery
0.200
Therapeutic
RGD
Protective effect of treatment with low-dose gliclazide in a model of middle cerebral artery occlusion and reperfusion in rats.
24602692 2014
×
Entrez Id: 7124
Gene Symbol: TNF
TNF
Infarction, Middle Cerebral Artery
0.200
Therapeutic
RGD
Hypertonic saline alleviates cerebral edema by inhibiting microglia-derived TNF-α and IL-1β-induced Na-K-Cl Cotransporter up-regulation.
24916922 2014
×
Entrez Id: 861
Gene Symbol: RUNX1
RUNX1
Infarction, Middle Cerebral Artery
0.200
Biomarker
RGD
Transcriptomics of post-stroke angiogenesis in the aged brain.
24672479 2014
×
Entrez Id: 1636
Gene Symbol: ACE
ACE
Infarction, Middle Cerebral Artery
0.200
Therapeutic
RGD
Enalapril attenuates ischaemic brain oedema and protects the blood-brain barrier in rats via an anti-oxidant action.
24471927 2014
×
Entrez Id: 7122
Gene Symbol: CLDN5
CLDN5
Infarction, Middle Cerebral Artery
0.200
Therapeutic
RGD
Protective effect of naringenin in experimental ischemic stroke: down-regulated NOD2, RIP2, NF-κB, MMP-9 and up-regulated claudin-5 expression.
24842554 2014
×
Entrez Id: 177
Gene Symbol: AGER
AGER
Infarction, Middle Cerebral Artery
0.200
Biomarker
RGD
Neamine induces neuroprotection after acute ischemic stroke in type one diabetic rats.
24211797 2014
×
Entrez Id: 2475
Gene Symbol: MTOR
MTOR
Infarction, Middle Cerebral Artery
0.200
Biomarker
RGD
PRAS40 plays a pivotal role in protecting against stroke by linking the Akt and mTOR pathways.
24583056 2014
×
Entrez Id: 1728
Gene Symbol: NQO1
NQO1
Infarction, Middle Cerebral Artery
0.200
Therapeutic
RGD
Danhong injection attenuates ischemia/reperfusion-induced brain damage which is associating with Nrf2 levels in vivo and in vitro.
25069640 2014
×
Entrez Id: 64127
Gene Symbol: NOD2
NOD2
Infarction, Middle Cerebral Artery
0.200
Therapeutic
RGD
Protective effect of naringenin in experimental ischemic stroke: down-regulated NOD2, RIP2, NF-κB, MMP-9 and up-regulated claudin-5 expression.
24842554 2014
×
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2
Infarction, Middle Cerebral Artery
0.200
Therapeutic
RGD
Lipoxin A4 ameliorates cerebral ischaemia/reperfusion injury through upregulation of nuclear factor erythroid 2-related factor 2.
23880501 2013
×
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2
Infarction, Middle Cerebral Artery
0.200
Therapeutic
RGD
Eriodictyol-7-O-glucoside activates Nrf2 and protects against cerebral ischemic injury.
24466583 2013
×
Entrez Id: 56963
Gene Symbol: RGMA
RGMA
Infarction, Middle Cerebral Artery
0.200
Therapeutic
RGD
CRMP-2 is involved in axon growth inhibition induced by RGMa in vitro and in vivo.
23275173 2013
×
Entrez Id: 10014
Gene Symbol: HDAC5
HDAC5
Infarction, Middle Cerebral Artery
0.200
Therapeutic
RGD
HDAC4/5-HMGB1 signalling mediated by NADPH oxidase activity contributes to cerebral ischaemia/reperfusion injury.
23480850 2013
×
Entrez Id: 183
Gene Symbol: AGT
AGT
Infarction, Middle Cerebral Artery
0.200
Biomarker
RGD
The expression of angiotensin-converting enzyme 2-angiotensin-(1-7)-Mas receptor axis are upregulated after acute cerebral ischemic stroke in rats.
24090950 2013
×
Entrez Id: 6608
Gene Symbol: SMO
SMO
Infarction, Middle Cerebral Artery
0.200
Therapeutic
RGD
Sonic hedgehog signaling pathway mediates cerebrolysin-improved neurological function after stroke.
23696546 2013
×
Entrez Id: 1965
Gene Symbol: EIF2S1
EIF2S1
Infarction, Middle Cerebral Artery
0.200
Therapeutic
RGD
Pinocembrin protects brain against ischemia/reperfusion injury by attenuating endoplasmic reticulum stress induced apoptosis.
23669639 2013
×
Entrez Id: 1788
Gene Symbol: DNMT3A
DNMT3A
Infarction, Middle Cerebral Artery
0.200
Biomarker
RGD
MicroRNA miR-29c down-regulation leading to de-repression of its target DNA methyltransferase 3a promotes ischemic brain damage.
23516428 2013
×
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
Infarction, Middle Cerebral Artery
0.200
Therapeutic
RGD
Citicoline (CDP-choline) increases Sirtuin1 expression concomitant to neuroprotection in experimental stroke.
23600725 2013
×
Entrez Id: 3146
Gene Symbol: HMGB1
HMGB1
Infarction, Middle Cerebral Artery
0.200
Therapeutic
RGD
HDAC4/5-HMGB1 signalling mediated by NADPH oxidase activity contributes to cerebral ischaemia/reperfusion injury.
23480850 2013
×
Entrez Id: 317
Gene Symbol: APAF1
APAF1
Infarction, Middle Cerebral Artery
0.200
Therapeutic
RGD
Protective effect of flavonoid-rich extract from Rosa laevigata Michx on cerebral ischemia-reperfusion injury through suppression of apoptosis and inflammation.
24012531 2013
×
Entrez Id: 9759
Gene Symbol: HDAC4
HDAC4
Infarction, Middle Cerebral Artery
0.200
Therapeutic
RGD
HDAC4/5-HMGB1 signalling mediated by NADPH oxidase activity contributes to cerebral ischaemia/reperfusion injury.
23480850 2013