| Gene | Gene Full Name | DSI g | DPI g | pLI | Disease | Type | Score gda | EL gda | EI gda | N. PMIDs | N. SNPs gda | First Ref. | Last Ref. | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
KRAS proto-oncogene, GTPase | 0.320 | 0.923 | 7.9E-04 |
|
disease | 0.500 | None | 1.000 | 29 | 2 | 1987 | 2019 | ||||||||
|
toll like receptor 4 | 0.321 | 0.962 | 4.6E-09 |
|
disease | 0.100 | None | 1.000 | 27 | 6 | 2007 | 2020 | ||||||||
|
C-C motif chemokine ligand 2 | 0.321 | 0.962 | 0.61 |
|
disease | 0.070 | None | 0.857 | 7 | 0 | 2008 | 2018 | ||||||||
|
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta | 0.322 | 0.885 | 1.00 |
|
disease | 0.100 | None | 0.990 | 98 | 0 | 2005 | 2020 | ||||||||
|
single-strand-selective monofunctional uracil-DNA glycosylase 1 | 0.322 | 0.923 | 4.5E-04 |
|
disease | 0.020 | None | 1.000 | 2 | 0 | 2017 | 2019 | ||||||||
|
CD274 molecule | 0.324 | 0.923 | 1.9E-02 |
|
disease | 0.100 | None | 0.975 | 80 | 1 | 2012 | 2020 | ||||||||
|
interleukin 17A | 0.324 | 0.923 | 4.3E-02 |
|
disease | 0.100 | None | 1.000 | 37 | 8 | 2009 | 2020 | ||||||||
|
estrogen receptor 1 | 0.324 | 0.962 | 1.00 |
|
disease | 0.100 | None | 1.000 | 14 | 0 | 2004 | 2019 | ||||||||
|
actin beta | 0.325 | 0.923 | 0.99 |
|
disease | 0.020 | None | 1.000 | 2 | 0 | 2017 | 2018 | ||||||||
|
hypoxia inducible factor 1 subunit alpha | 0.327 | 0.923 | 0.98 |
|
disease | 0.100 | None | 0.976 | 41 | 0 | 2008 | 2019 | ||||||||
|
erb-b2 receptor tyrosine kinase 2 | 0.328 | 0.923 | 6.0E-03 |
|
disease | 0.700 | None | 0.963 | 377 | 4 | 1988 | 2020 | ||||||||
|
angiotensin I converting enzyme | 0.328 | 0.923 | 1.0E-37 |
|
disease | 0.370 | None | 1.000 | 7 | 0 | 2005 | 2015 | ||||||||
|
mitogen-activated protein kinase 1 | 0.330 | 0.923 | 1.00 |
|
disease | 0.400 | None | 1.000 | 26 | 1 | 1994 | 2019 | ||||||||
|
colony stimulating factor 2 | 0.330 | 0.962 | 0.83 |
|
disease | 0.020 | None | 1.000 | 2 | 0 | 2017 | 2017 | ||||||||
|
interleukin 4 | 0.332 | 0.962 | 4.7E-03 |
|
disease | 0.080 | None | 1.000 | 8 | 2 | 2007 | 2019 | ||||||||
|
interleukin 1 alpha | 0.333 | 0.962 | 1.6E-04 |
|
disease | 0.100 | None | 0.909 | 22 | 2 | 2003 | 2018 | ||||||||
|
matrix metallopeptidase 2 | 0.333 | 0.923 | 0.84 |
|
disease | 0.100 | None | 0.950 | 20 | 1 | 2003 | 2019 | ||||||||
|
major histocompatibility complex, class II, DR beta 1 | 0.333 | 0.923 | 1.1E-03 |
|
disease | 0.010 | None | 1.000 | 1 | 0 | 2009 | 2009 | ||||||||
|
interleukin 2 | 0.336 | 0.885 | 0.48 |
|
disease | 0.050 | None | 1.000 | 5 | 1 | 2008 | 2018 | ||||||||
|
methylenetetrahydrofolate reductase | 0.337 | 0.885 | 3.2E-10 |
|
disease | 0.400 | None | 0.951 | 40 | 4 | 2001 | 2019 | ||||||||
|
apolipoprotein E | 0.338 | 0.962 | 1.9E-03 |
|
disease | 0.020 | None | 1.000 | 2 | 0 | 2012 | 2016 | ||||||||
|
mechanistic target of rapamycin kinase | 0.343 | 0.885 | 1.00 |
|
disease | 0.100 | None | 1.000 | 13 | 2 | 2012 | 2019 | ||||||||
|
ATP binding cassette subfamily B member 1 | 0.344 | 0.885 | 1.3E-05 |
|
disease | 0.100 | None | 0.946 | 37 | 2 | 1992 | 2019 | ||||||||
|
cyclin D1 | 0.344 | 0.923 | 0.89 |
|
disease | 0.400 | None | 0.926 | 26 | 0 | 2001 | 2019 | ||||||||
|
MYC proto-oncogene, bHLH transcription factor | 0.344 | 0.923 | 1.00 |
|
disease | 0.400 | None | 1.000 | 22 | 0 | 1995 | 2019 |