Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3552
Gene Symbol: IL1A
IL1A
interleukin 1 alpha 0.333 0.962 1.6E-04
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.320 None 1.000 1 0 1993 2017
Entrez Id: 3146
Gene Symbol: HMGB1
HMGB1
high mobility group box 1 0.368 0.923 0.82
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.320 None 1.000 1 0 2009 2019
Entrez Id: 3875
Gene Symbol: KRT18
KRT18
keratin 18 0.530 0.692 0.73
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.320 None 1.000 1 0 1997 2017
Entrez Id: 335
Gene Symbol: APOA1
APOA1
apolipoprotein A1 0.429 0.885 5.5E-04
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.320 None 1.000 1 0 2005 2017
Entrez Id: 406967
Gene Symbol: MIR192
MIR192
microRNA 192 0.503 0.846
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.310 None 1.000 4 0 2011 2018
Entrez Id: 406884
Gene Symbol: MIRLET7B
MIRLET7B
microRNA let-7b 0.493 0.769
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.310 None 1.000 2 0 2017 2018
Entrez Id: 1647
Gene Symbol: GADD45A
GADD45A
growth arrest and DNA damage inducible alpha 0.526 0.769 4.4E-02
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.310 None 1.000 1 0 2011 2019
Entrez Id: 1544
Gene Symbol: CYP1A2
CYP1A2
cytochrome P450 family 1 subfamily A member 2 0.494 0.923 2.5E-10
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.310 None 1.000 1 0 2014 2018
Entrez Id: 1373
Gene Symbol: CPS1
CPS1
carbamoyl-phosphate synthase 1 0.590 0.615 1.1E-09
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.310 None 1.000 1 0 2015 2015
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
prostaglandin-endoperoxide synthase 2 0.314 0.962 1.00
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.310 None 1.000 1 0 2001 2019
Entrez Id: 54600
Gene Symbol: UGT1A9
UGT1A9
UDP glucuronosyltransferase family 1 member A9 0.590 0.577 5.4E-08
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.310 None 1.000 1 0 2011 2015
Entrez Id: 6648
Gene Symbol: SOD2
SOD2
superoxide dismutase 2 0.379 0.923 0.15
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.310 None 1.000 1 0 2010 2014
Entrez Id: 1576
Gene Symbol: CYP3A4
CYP3A4
cytochrome P450 family 3 subfamily A member 4 0.462 0.885 5.8E-11
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.310 None 1.000 1 0 2013 2018
Entrez Id: 6590
Gene Symbol: SLPI
SLPI
secretory leukocyte peptidase inhibitor 0.449 0.846 9.0E-04
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.310 None 1.000 1 0 2007 2017
Entrez Id: 348
Gene Symbol: APOE
APOE
apolipoprotein E 0.338 0.962 1.9E-03
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.310 None 1.000 1 0 2005 2012
Entrez Id: 5465
Gene Symbol: PPARA
PPARA
peroxisome proliferator activated receptor alpha 0.432 0.885 3.0E-02
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.310 None 1.000 1 0 2014 2019
Entrez Id: 6696
Gene Symbol: SPP1
SPP1
secreted phosphoprotein 1 0.353 0.885 2.1E-06
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.310 None 1.000 1 0 2011 2019
Entrez Id: 2494
Gene Symbol: NR5A2
NR5A2
nuclear receptor subfamily 5 group A member 2 0.563 0.731 0.24
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.310 None 1.000 1 0 2015 2018
Entrez Id: 196
Gene Symbol: AHR
AHR
aryl hydrocarbon receptor 0.410 0.923 1.00
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.310 None 1.000 1 0 2011 2017
Entrez Id: 3119
Gene Symbol: HLA-DQB1
HLA-DQB1
major histocompatibility complex, class II, DQ beta 1 0.407 0.885 8.9E-03
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.310 None 1.000 1 0 2011 2015
Entrez Id: 5444
Gene Symbol: PON1
PON1
paraoxonase 1 0.409 0.885 9.8E-11
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.310 None 1.000 1 0 2005 2019
Entrez Id: 3627
Gene Symbol: CXCL10
CXCL10
C-X-C motif chemokine ligand 10 0.378 0.885 0.37
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.310 None 1.000 1 0 2001 2018
Entrez Id: 1401
Gene Symbol: CRP
CRP
C-reactive protein 0.299 0.962 3.7E-03
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.310 None 1.000 1 0 2015 2019
Entrez Id: 4363
Gene Symbol: ABCC1
ABCC1
ATP binding cassette subfamily C member 1 0.445 0.808 1.2E-03
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.310 None 1.000 1 0 2008 2020
Entrez Id: 8431
Gene Symbol: NR0B2
NR0B2
nuclear receptor subfamily 0 group B member 2 0.474 0.808 8.3E-06
CUI: C0860207
Disease: Drug-Induced Liver Disease
Drug-Induced Liver Disease
phenotype 0.310 None 1.000 1 0 2018 2018