Source: CURATED

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 4313
Gene Symbol: MMP2
MMP2 		matrix metallopeptidase 2 0.333 0.923 0.84
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.300 None 1.000 1 0 2005 2005
Entrez Id: 229
Gene Symbol: ALDOB
ALDOB 		aldolase, fructose-bisphosphate B 0.623 0.538 7.9E-07
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.300 None 1.000 1 0 2005 2005
Entrez Id: 4057
Gene Symbol: LTF
LTF 		lactotransferrin 0.543 0.846 1.3E-21
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.300 None 1.000 1 0 2005 2005
Entrez Id: 1281
Gene Symbol: COL3A1
COL3A1 		collagen type III alpha 1 chain 0.477 0.808 1.00
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.300 None 1.000 1 0 2006 2006
Entrez Id: 10062
Gene Symbol: NR1H3
NR1H3 		nuclear receptor subfamily 1 group H member 3 0.566 0.692 0.90
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.300 None 1.000 1 0 2007 2007
Entrez Id: 84649
Gene Symbol: DGAT2
DGAT2 		diacylglycerol O-acyltransferase 2 0.686 0.423 8.4E-12
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.300 None 1.000 1 0 2007 2007
Entrez Id: 6590
Gene Symbol: SLPI
SLPI 		secretory leukocyte peptidase inhibitor 0.449 0.846 9.0E-04
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.300 None 1.000 1 0 2007 2007
Entrez Id: 7850
Gene Symbol: IL1R2
IL1R2 		interleukin 1 receptor type 2 0.593 0.846 6.5E-15
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.300 None 1.000 1 0 2007 2007
Entrez Id: 112574
Gene Symbol: SNX18
SNX18 		sorting nexin 18 0.839 0.077 0.96
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.300 None 1.000 1 0 2007 2007
Entrez Id: 79600
Gene Symbol: TCTN1
TCTN1 		tectonic family member 1 0.597 0.615 1.1E-15
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.300 None 1.000 1 0 2007 2007
Entrez Id: 1244
Gene Symbol: ABCC2
ABCC2 		ATP binding cassette subfamily C member 2 0.483 0.808 5.2E-47
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.300 None 1.000 2 0 2008 2008
Entrez Id: 581
Gene Symbol: BAX
BAX 		BCL2 associated X, apoptosis regulator 0.417 0.885 0.32
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.300 None 1.000 1 0 2008 2008
Entrez Id: 4363
Gene Symbol: ABCC1
ABCC1 		ATP binding cassette subfamily C member 1 0.445 0.808 1.2E-03
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.300 None 1.000 1 0 2008 2008
Entrez Id: 4217
Gene Symbol: MAP3K5
MAP3K5 		mitogen-activated protein kinase kinase kinase 5 0.513 0.808 0.52
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.300 None 1.000 1 0 2008 2008
Entrez Id: 259
Gene Symbol: AMBP
AMBP 		alpha-1-microglobulin/bikunin precursor 0.537 0.731 2.8E-13
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.300 None 1.000 1 0 2008 2008
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR 		methylenetetrahydrofolate reductase 0.337 0.885 3.2E-10
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.300 None 1.000 2 0 2008 2009
Entrez Id: 3146
Gene Symbol: HMGB1
HMGB1 		high mobility group box 1 0.368 0.923 0.82
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.300 None 1.000 1 0 2009 2009
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1 		catenin beta 1 0.303 0.885 1.00
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.300 None 1.000 1 0 2009 2009
Entrez Id: 6888
Gene Symbol: TALDO1
TALDO1 		transaldolase 1 0.608 0.654 2.5E-06
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.300 None 1.000 1 0 2009 2009
Entrez Id: 3875
Gene Symbol: KRT18
KRT18 		keratin 18 0.530 0.692 0.73
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.300 None 1.000 1 0 2009 2009
Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B 		major histocompatibility complex, class I, B 0.379 0.885 3.9E-05
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.300 None 1.000 1 0 2009 2009
Entrez Id: 1719
Gene Symbol: DHFR
DHFR 		dihydrofolate reductase 0.513 0.808 3.4E-02
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.300 None 1.000 1 0 2009 2009
Entrez Id: 2729
Gene Symbol: GCLC
GCLC 		glutamate-cysteine ligase catalytic subunit 0.509 0.885 0.43
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.500 None 1.000 1 0 2007 2009
Entrez Id: 3606
Gene Symbol: IL18
IL18 		interleukin 18 0.365 0.923 3.1E-02
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.300 None 1.000 1 0 2009 2009
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ 		adiponectin, C1Q and collagen domain containing 0.376 0.885 4.6E-09
CUI: C4277682
Disease: Chemical and Drug Induced Liver Injury
Chemical and Drug Induced Liver Injury 		disease 0.300 None 1.000 1 0 2010 2010