Source: CLINVAR

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 2475
Gene Symbol: MTOR
MTOR
mechanistic target of rapamycin kinase 0.343 0.885 1.00
CUI: C0151779
Disease: Cutaneous Melanoma
Cutaneous Melanoma
disease 0.100 None 1.000 1 2 2016 2016
Entrez Id: 4609
Gene Symbol: MYC
MYC
MYC proto-oncogene, bHLH transcription factor 0.344 0.923 1.00
CUI: C0151779
Disease: Cutaneous Melanoma
Cutaneous Melanoma
disease 0.100 None 1.000 1 3 2016 2016
Entrez Id: 4893
Gene Symbol: NRAS
NRAS
NRAS proto-oncogene, GTPase 0.390 0.808 0.49
CUI: C0151779
Disease: Cutaneous Melanoma
Cutaneous Melanoma
disease 0.500 None 0.967 1 6 2001 2020
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha 0.292 0.923 1.00
CUI: C0151779
Disease: Cutaneous Melanoma
Cutaneous Melanoma
disease 0.410 None 1.000 1 11 2006 2016
Entrez Id: 5295
Gene Symbol: PIK3R1
PIK3R1
phosphoinositide-3-kinase regulatory subunit 1 0.477 0.885 1.00
CUI: C0151779
Disease: Cutaneous Melanoma
Cutaneous Melanoma
disease 0.100 None 1.000 1 2 2016 2016
Entrez Id: 5537
Gene Symbol: PPP6C
PPP6C
protein phosphatase 6 catalytic subunit 0.729 0.231 0.86
CUI: C0151779
Disease: Cutaneous Melanoma
Cutaneous Melanoma
disease 0.400 None 1.000 1 1 2016 2016
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
phosphatase and tensin homolog 0.305 0.923 0.26
CUI: C0151779
Disease: Cutaneous Melanoma
Cutaneous Melanoma
disease 0.440 None 1.000 1 2 2000 2016
Entrez Id: 5879
Gene Symbol: RAC1
RAC1
Rac family small GTPase 1 0.429 0.962 0.76
CUI: C0151779
Disease: Cutaneous Melanoma
Cutaneous Melanoma
disease 0.440 None 1.000 1 2 2014 2019
Entrez Id: 5894
Gene Symbol: RAF1
RAF1
Raf-1 proto-oncogene, serine/threonine kinase 0.418 0.885 0.85
CUI: C0151779
Disease: Cutaneous Melanoma
Cutaneous Melanoma
disease 0.440 None 1.000 1 1 2005 2016
Entrez Id: 23451
Gene Symbol: SF3B1
SF3B1
splicing factor 3b subunit 1 0.511 0.731 1.00
CUI: C0151779
Disease: Cutaneous Melanoma
Cutaneous Melanoma
disease 0.140 None 1.000 1 3 2013 2020
Entrez Id: 10992
Gene Symbol: SF3B2
SF3B2
splicing factor 3b subunit 2 0.780 0.308 1.00
CUI: C0151779
Disease: Cutaneous Melanoma
Cutaneous Melanoma
disease 0.100 None 1.000 1 1 2016 2016
Entrez Id: 8859
Gene Symbol: STK19
STK19
serine/threonine kinase 19 0.691 0.500 6.7E-09
CUI: C0151779
Disease: Cutaneous Melanoma
Cutaneous Melanoma
disease 0.100 None 1.000 1 1 2016 2016
Entrez Id: 7157
Gene Symbol: TP53
TP53
tumor protein p53 0.236 0.962 0.53
CUI: C0151779
Disease: Cutaneous Melanoma
Cutaneous Melanoma
disease 0.500 None 0.963 1 38 1994 2019