Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 632
Gene Symbol: BGLAP
BGLAP
CUI: C2316810
Disease: Chronic kidney disease stage 5
Chronic kidney disease stage 5
0.210 Biomarker RGD Role of dietary phosphorus and degree of uremia in the development of renal bone disease in rats. 17365904

2007

Entrez Id: 1536
Gene Symbol: CYBB
CYBB
CUI: C2316810
Disease: Chronic kidney disease stage 5
Chronic kidney disease stage 5
0.210 Biomarker RGD Iron and oxidative stress in renal insufficiency. 15550752

2005

Entrez Id: 5328
Gene Symbol: PLAU
PLAU
CUI: C2316810
Disease: Chronic kidney disease stage 5
Chronic kidney disease stage 5
0.210 Biomarker RGD [Curative machanism of Shenle capsule on 5/6 nephrectomy rats]. 15506291

2004

Entrez Id: 2057
Gene Symbol: EPOR
EPOR
CUI: C2316810
Disease: Chronic kidney disease stage 5
Chronic kidney disease stage 5
0.200 Biomarker RGD Down-Regulation of Cardiac Erythropoietin Receptor and its Downstream Activated Signal Transducer Phospho-STAT-5 in a Rat Model of Chronic Kidney Disease. 27468524

2016

Entrez Id: 664
Gene Symbol: BNIP3
BNIP3
CUI: C2316810
Disease: Chronic kidney disease stage 5
Chronic kidney disease stage 5
0.200 Biomarker RGD Mitochondrial impairment in the five-sixth nephrectomy model of chronic renal failure: proteomic approach. 24090408

2013

Entrez Id: 6582
Gene Symbol: SLC22A2
SLC22A2
CUI: C2316810
Disease: Chronic kidney disease stage 5
Chronic kidney disease stage 5
0.200 Biomarker RGD Renal uptake of substrates for organic anion transporters Oat1 and Oat3 and organic cation transporters Oct1 and Oct2 is altered in rats with adenine-induced chronic renal failure. 23280877

2013

Entrez Id: 8678
Gene Symbol: BECN1
BECN1
CUI: C2316810
Disease: Chronic kidney disease stage 5
Chronic kidney disease stage 5
0.200 Biomarker RGD Mitochondrial impairment in the five-sixth nephrectomy model of chronic renal failure: proteomic approach. 24090408

2013

Entrez Id: 3667
Gene Symbol: IRS1
IRS1
CUI: C2316810
Disease: Chronic kidney disease stage 5
Chronic kidney disease stage 5
0.200 Biomarker RGD Vascular insulin resistance related to endoplasmic reticulum stress in aortas from a rat model of chronic kidney disease. 22942179

2012

Entrez Id: 4023
Gene Symbol: LPL
LPL
CUI: C2316810
Disease: Chronic kidney disease stage 5
Chronic kidney disease stage 5
0.200 Biomarker RGD Lipoprotein lipase deficiency in chronic kidney disease is accompanied by down-regulation of endothelial GPIHBP1 expression. 22009636

2012

Entrez Id: 2147
Gene Symbol: F2
F2
CUI: C2316810
Disease: Chronic kidney disease stage 5
Chronic kidney disease stage 5
0.200 Therapeutic RGD 5/6 nephrectomy as a validated rat model mimicking human warfarin-related nephropathy. 22473220

2012

Entrez Id: 10631
Gene Symbol: POSTN
POSTN
CUI: C2316810
Disease: Chronic kidney disease stage 5
Chronic kidney disease stage 5
0.200 Biomarker RGD Periostin: novel tissue and urinary biomarker of progressive renal injury induces a coordinated mesenchymal phenotype in tubular cells. 22167593

2012

Entrez Id: 2475
Gene Symbol: MTOR
MTOR
CUI: C2316810
Disease: Chronic kidney disease stage 5
Chronic kidney disease stage 5
0.200 Therapeutic RGD Delayed mTOR inhibition with low dose of everolimus reduces TGFβ expression, attenuates proteinuria and renal damage in the renal mass reduction model. 22427849

2012

Entrez Id: 3156
Gene Symbol: HMGCR
HMGCR
CUI: C2316810
Disease: Chronic kidney disease stage 5
Chronic kidney disease stage 5
0.200 Biomarker RGD Inhibition of mineralocorticoid receptor is a renoprotective effect of the 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor pitavastatin. 21119529

2011

Entrez Id: 847
Gene Symbol: CAT
CAT
CUI: C2316810
Disease: Chronic kidney disease stage 5
Chronic kidney disease stage 5
0.200 Biomarker RGD Contribution of impaired Nrf2-Keap1 pathway to oxidative stress and inflammation in chronic renal failure. 20007347

2010

Entrez Id: 38
Gene Symbol: ACAT1
ACAT1
CUI: C2316810
Disease: Chronic kidney disease stage 5
Chronic kidney disease stage 5
0.200 Biomarker RGD Niacin improves renal lipid metabolism and slows progression in chronic kidney disease. 19878707

2010

Entrez Id: 10
Gene Symbol: NAT2
NAT2
CUI: C2316810
Disease: Chronic kidney disease stage 5
Chronic kidney disease stage 5
0.200 Biomarker RGD Down-regulation of liver drug-metabolizing enzymes in a murine model of chronic renal failure. 20007296

2010

Entrez Id: 9817
Gene Symbol: KEAP1
KEAP1
CUI: C2316810
Disease: Chronic kidney disease stage 5
Chronic kidney disease stage 5
0.200 Biomarker RGD Contribution of impaired Nrf2-Keap1 pathway to oxidative stress and inflammation in chronic renal failure. 20007347

2010

Entrez Id: 1644
Gene Symbol: DDC
DDC
CUI: C2316810
Disease: Chronic kidney disease stage 5
Chronic kidney disease stage 5
0.200 Biomarker RGD Renal dopaminergic system activity in rat remnant kidney up to twenty-six weeks after surgery. 19167406

2009

Entrez Id: 1812
Gene Symbol: DRD1
DRD1
CUI: C2316810
Disease: Chronic kidney disease stage 5
Chronic kidney disease stage 5
0.200 Therapeutic RGD Delivery of recombinant adeno-associated virus-mediated human tissue kallikrein for therapy of chronic renal failure in rats. 18402547

2008

Entrez Id: 50604
Gene Symbol: IL20
IL20
CUI: C2316810
Disease: Chronic kidney disease stage 5
Chronic kidney disease stage 5
0.200 Biomarker RGD Interleukin-20 targets renal cells and is associated with chronic kidney disease. 18639518

2008

Entrez Id: 5970
Gene Symbol: RELA
RELA
CUI: C2316810
Disease: Chronic kidney disease stage 5
Chronic kidney disease stage 5
0.200 Biomarker RGD Melatonin ameliorates oxidative stress, inflammation, proteinuria, and progression of renal damage in rats with renal mass reduction. 18077597

2008

Entrez Id: 1244
Gene Symbol: ABCC2
ABCC2
CUI: C2316810
Disease: Chronic kidney disease stage 5
Chronic kidney disease stage 5
0.200 Biomarker RGD Down-regulation of intestinal drug transporters in chronic renal failure in rats. 17135344

2007

Entrez Id: 8714
Gene Symbol: ABCC3
ABCC3
CUI: C2316810
Disease: Chronic kidney disease stage 5
Chronic kidney disease stage 5
0.200 Biomarker RGD Down-regulation of intestinal drug transporters in chronic renal failure in rats. 17135344

2007

Entrez Id: 6721
Gene Symbol: SREBF2
SREBF2
CUI: C2316810
Disease: Chronic kidney disease stage 5
Chronic kidney disease stage 5
0.200 Biomarker RGD Increased gene expression of liver SREBP-2 in experimental chronic renal failure. 16814791

2007

Entrez Id: 384
Gene Symbol: ARG2
ARG2
CUI: C2316810
Disease: Chronic kidney disease stage 5
Chronic kidney disease stage 5
0.200 Biomarker RGD Effect of chronic renal failure on arginase and argininosuccinate synthetase expression. 16809898

2006