Source: CTD_human

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 26191
Gene Symbol: PTPN22
PTPN22
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.700 Biomarker CTD_human Fine-mapping and functional studies highlight potential causal variants for rheumatoid arthritis and type 1 diabetes. 30224649

2018
Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.700 Therapeutic CTD_human Modulation of the oxidative stress and inflammatory cytokine response by thymoquinone in the collagen induced arthritis in Wistar rats. 22450443

2012
Entrez Id: 26191
Gene Symbol: PTPN22
PTPN22
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.700 Biomarker CTD_human High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis. 23143596

2012
Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.700 Biomarker CTD_human Modulation of the oxidative stress and inflammatory cytokine response by thymoquinone in the collagen induced arthritis in Wistar rats. 22450443

2012
Entrez Id: 26191
Gene Symbol: PTPN22
PTPN22
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.700 Biomarker CTD_human Inhibition of lymphoid tyrosine phosphatase by benzofuran salicylic acids. 21190368

2011
Entrez Id: 26191
Gene Symbol: PTPN22
PTPN22
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.700 Biomarker CTD_human Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci. 20453842

2010
Entrez Id: 26191
Gene Symbol: PTPN22
PTPN22
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.700 Biomarker CTD_human Specific interaction between genotype, smoking and autoimmunity to citrullinated alpha-enolase in the etiology of rheumatoid arthritis. 19898480

2009
Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.700 Therapeutic CTD_human Suppression of human monocyte interleukin-1beta production by ajulemic acid, a nonpsychoactive cannabinoid. 12566094

2003
Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.700 Biomarker CTD_human Suppression of human monocyte interleukin-1beta production by ajulemic acid, a nonpsychoactive cannabinoid. 12566094

2003
Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.700 Therapeutic CTD_human TNF-alpha in rheumatoid arthritis and prospects of anti-TNF therapy. 8391952

1993
Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.700 Biomarker CTD_human TNF-alpha in rheumatoid arthritis and prospects of anti-TNF therapy. 8391952

1993
Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.700 Therapeutic CTD_human Tumor necrosis factor alpha (TNF) and interleukin-1 (IL-1) production by alveolar macrophages (AM) was evaluated in 17 rheumatoid arthritis (RA) patients without interstitial lung disease (ILD, Group 1) and 14 RA patients with clinical ILD (Group 2) in comparison with 10 control subjects. 2001072

1991
Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.700 Biomarker CTD_human Tumor necrosis factor alpha (TNF) and interleukin-1 (IL-1) production by alveolar macrophages (AM) was evaluated in 17 rheumatoid arthritis (RA) patients without interstitial lung disease (ILD, Group 1) and 14 RA patients with clinical ILD (Group 2) in comparison with 10 control subjects. 2001072

1991
Entrez Id: 6583
Gene Symbol: SLC22A4
SLC22A4
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.700 Biomarker CTD_human

Entrez Id: 1401
Gene Symbol: CRP
CRP
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.600 Biomarker CTD_human Multiple intra-articular treatment of rheumatoid arthritis: a randomized prospective study comparing rifamycin SV with pefloxacin. 1568518

1992
Entrez Id: 3572
Gene Symbol: IL6ST
IL6ST
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.590 Biomarker CTD_human Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci. 20453842

2010
Entrez Id: 7128
Gene Symbol: TNFAIP3
TNFAIP3
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.500 Biomarker CTD_human Fine-mapping and functional studies highlight potential causal variants for rheumatoid arthritis and type 1 diabetes. 30224649

2018
Entrez Id: 3115
Gene Symbol: HLA-DPB1
HLA-DPB1
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.500 Biomarker CTD_human Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis. 22286218

2012
Entrez Id: 3663
Gene Symbol: IRF5
IRF5
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.500 Biomarker CTD_human High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis. 23143596

2012
Entrez Id: 3559
Gene Symbol: IL2RA
IL2RA
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.500 Biomarker CTD_human High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis. 23143596

2012
Entrez Id: 6775
Gene Symbol: STAT4
STAT4
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.500 Biomarker CTD_human High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis. 23143596

2012
Entrez Id: 2212
Gene Symbol: FCGR2A
FCGR2A
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.500 Biomarker CTD_human High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis. 23143596

2012
Entrez Id: 940
Gene Symbol: CD28
CD28
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.500 Biomarker CTD_human High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis. 23143596

2012
Entrez Id: 958
Gene Symbol: CD40
CD40
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.500 Biomarker CTD_human High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis. 23143596

2012
Entrez Id: 7189
Gene Symbol: TRAF6
TRAF6
CUI: C0003873
Disease: Rheumatoid Arthritis
Rheumatoid Arthritis 		0.500 Biomarker CTD_human High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis. 23143596

2012