×
Entrez Id: 7124
Gene Symbol: TNF
TNF
Rheumatoid Arthritis
0.700
GeneticVariation
LHGDN
Rheumatoid arthritis patients showed high TNFalpha mRNA expression (1.33-fold).18797411 2008
×
Entrez Id: 26191
Gene Symbol: PTPN22
PTPN22
Rheumatoid Arthritis
0.700
GeneticVariation
LHGDN
Auto-antibodies, HLA and PTPN22: susceptibility markers for rheumatoid arthritis.
18156150 2008
×
Entrez Id: 6583
Gene Symbol: SLC22A4
SLC22A4
Rheumatoid Arthritis
0.700
GeneticVariation
LHGDN
Replication of reported genetic associations of PADI4, FCRL3, SLC22A4 and RUNX1 genes with rheumatoid arthritis: results of an independent Japanese population and evidence from meta-analysis of East Asian studies.
18087673 2008
×
Entrez Id: 7124
Gene Symbol: TNF
TNF
Rheumatoid Arthritis
0.700
Biomarker
LHGDN
BAT1 promoter polymorphism is associated with rheumatoid arthritis susceptibility.
18381799 2008
×
Entrez Id: 7124
Gene Symbol: TNF
TNF
Rheumatoid Arthritis
0.700
AlteredExpression
LHGDN
Potential novel biomarkers of disease activity in rheumatoid arthritis patients: CXCL13, CCL23, transforming growth factor alpha, tumor necrosis factor receptor superfamily member 9, and macrophage colony-stimulating factor.
18668547 2008
×
Entrez Id: 7124
Gene Symbol: TNF
TNF
Rheumatoid Arthritis
0.700
Biomarker
LHGDN
Inhibitors of TLR8 reduce TNF production from human rheumatoid synovial membrane cultures.
19017992 2008
×
Entrez Id: 7124
Gene Symbol: TNF
TNF
Rheumatoid Arthritis
0.700
GeneticVariation
LHGDN
Polymorphism in the tumor necrosis factor-alpha gene promoter is associated with severity of rheumatoid arthritis in the Czech population.
17562093 2008
×
Entrez Id: 26191
Gene Symbol: PTPN22
PTPN22
Rheumatoid Arthritis
0.700
Biomarker
LHGDN
Genetic polymorphisms in PTPN22, PADI-4, and CTLA-4 and risk for rheumatoid arthritis in two longitudinal cohort studies: evidence of gene-environment interactions with heavy cigarette smoking.
18462498 2008
×
Entrez Id: 6583
Gene Symbol: SLC22A4
SLC22A4
Rheumatoid Arthritis
0.700
GeneticVariation
LHGDN
No influence of SLC22A4 C6607T and RUNX1 G24658C genotypic variants on the circulating carnitine ester profile in patients with rheumatoid arthritis.
18328148 2008
×
Entrez Id: 6583
Gene Symbol: SLC22A4
SLC22A4
Rheumatoid Arthritis
0.700
GeneticVariation
LHGDN
SLC22A4 polymorphism and rheumatoid arthritis susceptibility: a replication study in a Japanese population and a metaanalysis.
18709696 2008
×
Entrez Id: 7124
Gene Symbol: TNF
TNF
Rheumatoid Arthritis
0.700
Biomarker
LHGDN
Rheumatoid arthritis, periodontal disease and coronary artery disease.
17763921 2008
×
Entrez Id: 26191
Gene Symbol: PTPN22
PTPN22
Rheumatoid Arthritis
0.700
GeneticVariation
LHGDN
The PTPN22 promoter polymorphism -1123G>C association cannot be distinguished from the 1858C>T association in a Norwegian rheumatoid arthritis material.
17661906 2007
×
Entrez Id: 26191
Gene Symbol: PTPN22
PTPN22
Rheumatoid Arthritis
0.700
GeneticVariation
LHGDN
Gene-gene and gene-environment interactions involving HLA-DRB1, PTPN22, and smoking in two subsets of rheumatoid arthritis.
17436241 2007
×
Entrez Id: 7124
Gene Symbol: TNF
TNF
Rheumatoid Arthritis
0.700
GeneticVariation
LHGDN
Tumour necrosis factor (TNF)alpha -308 G/G promoter polymorphism and TNFalpha levels correlate with a better response to adalimumab in patients with rheumatoid arthritis.
17343250 2007
×
Entrez Id: 26191
Gene Symbol: PTPN22
PTPN22
Rheumatoid Arthritis
0.700
GeneticVariation
LHGDN
The 620W allele is the PTPN22 genetic variant conferring susceptibility to RA in a Dutch population.
17135225 2007
×
Entrez Id: 26191
Gene Symbol: PTPN22
PTPN22
Rheumatoid Arthritis
0.700
GeneticVariation
LHGDN
Association of PTPN22 with rheumatoid arthritis among South Asians in the UK.
17696275 2007
×
Entrez Id: 7124
Gene Symbol: TNF
TNF
Rheumatoid Arthritis
0.700
GeneticVariation
LHGDN
TNF microsatellites polymorphism is associated with rheumatoid arthritis. Confirming evidence in northwestern Colombians.
17631742 2007
×
Entrez Id: 26191
Gene Symbol: PTPN22
PTPN22
Rheumatoid Arthritis
0.700
GeneticVariation
LHGDN
Association of PTPN22 single nucleotide polymorphism with rheumatoid arthritis but not with allergic asthma.
17579671 2007
×
Entrez Id: 26191
Gene Symbol: PTPN22
PTPN22
Rheumatoid Arthritis
0.700
GeneticVariation
LHGDN
Investigation of genetic variation across the protein tyrosine phosphatase gene in patients with rheumatoid arthritis in the UK.
17170052 2007
×
Entrez Id: 7124
Gene Symbol: TNF
TNF
Rheumatoid Arthritis
0.700
AlteredExpression
LHGDN
Increased nuclear factor-kappaB activation in peripheral blood monocytes of patients with rheumatoid arthritis is mediated primarily by tumor necrosis factor-alpha.
17896809 2007
×
Entrez Id: 26191
Gene Symbol: PTPN22
PTPN22
Rheumatoid Arthritis
0.700
Biomarker
LHGDN
Linkage proof for PTPN22, a rheumatoid arthritis susceptibility gene and a human autoimmunity gene.
17237219 2007
×
Entrez Id: 26191
Gene Symbol: PTPN22
PTPN22
Rheumatoid Arthritis
0.700
Biomarker
LHGDN
Rheumatoid arthritis association with the FCRL3 -169C polymorphism is restricted to PTPN22 1858T-homozygous individuals in a Canadian population.
17133579 2006
×
Entrez Id: 7124
Gene Symbol: TNF
TNF
Rheumatoid Arthritis
0.700
GeneticVariation
LHGDN
Could single-nucleotide polymorphisms (SNPs) affecting the tumour necrosis factor promoter be considered as part of rheumatoid arthritis evolution?
16446172 2006
×
Entrez Id: 26191
Gene Symbol: PTPN22
PTPN22
Rheumatoid Arthritis
0.700
GeneticVariation
LHGDN
PTPN22 polymorphism and anti-cyclic citrullinated peptide antibodies in combination strongly predicts future onset of rheumatoid arthritis and has a specificity of 100% for the disease.
16507117 2006
×
Entrez Id: 7124
Gene Symbol: TNF
TNF
Rheumatoid Arthritis
0.700
AlteredExpression
LHGDN
Expression of TNF-alpha, tristetraprolin, T-cell intracellular antigen-1 and Hu antigen R genes in synovium of patients with rheumatoid arthritis.
16820934 2006