Source: ORPHANET

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4609
Gene Symbol: MYC
MYC
CUI: C0006413
Disease: Burkitt Lymphoma
Burkitt Lymphoma
1.000 FusionGene ORPHANET

Entrez Id: 6929
Gene Symbol: TCF3
TCF3
CUI: C0006413
Disease: Burkitt Lymphoma
Burkitt Lymphoma
0.580 FusionGene ORPHANET

Entrez Id: 5087
Gene Symbol: PBX1
PBX1
CUI: C0006413
Disease: Burkitt Lymphoma
Burkitt Lymphoma
0.500 FusionGene ORPHANET

Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0006413
Disease: Burkitt Lymphoma
Burkitt Lymphoma
0.400 SusceptibilityMutation ORPHANET Identification of TP53 as an acute lymphocytic leukemia susceptibility gene through exome sequencing. 23255406

2013

Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
CUI: C0006413
Disease: Burkitt Lymphoma
Burkitt Lymphoma
0.400 SomaticCausalMutation ORPHANET A comprehensive analysis of the CDKN2A gene in childhood acute lymphoblastic leukemia reveals genomic deletion, copy number neutral loss of heterozygosity, and association with specific cytogenetic subgroups. 18838613

2009

Entrez Id: 3492
Gene Symbol: IGH
IGH
CUI: C0006413
Disease: Burkitt Lymphoma
Burkitt Lymphoma
0.400 SomaticCausalMutation ORPHANET Presence of more than two rearranged immunoglobulin heavy-chain genes in adult precursor B-cell acute lymphoblastic leukemia. 1554798

1992

Entrez Id: 5079
Gene Symbol: PAX5
PAX5
CUI: C0006413
Disease: Burkitt Lymphoma
Burkitt Lymphoma
0.350 SusceptibilityMutation ORPHANET A recurrent germline PAX5 mutation confers susceptibility to pre-B cell acute lymphoblastic leukemia. 24013638

2013

Entrez Id: 5079
Gene Symbol: PAX5
PAX5
CUI: C0006413
Disease: Burkitt Lymphoma
Burkitt Lymphoma
0.350 FusionGene ORPHANET PAX5-AUTS2: a recurrent fusion gene in childhood B-cell precursor acute lymphoblastic leukemia. 22578776

2012

Entrez Id: 5079
Gene Symbol: PAX5
PAX5
CUI: C0006413
Disease: Burkitt Lymphoma
Burkitt Lymphoma
0.350 FusionGene ORPHANET FOXP1 and PAX5 are rare but recurrent translocations partners in acute lymphoblastic leukemia. 21962897

2011

Entrez Id: 5079
Gene Symbol: PAX5
PAX5
CUI: C0006413
Disease: Burkitt Lymphoma
Burkitt Lymphoma
0.350 FusionGene ORPHANET After cloning the full-length cDNA of the chimeric gene, confocal microscopy of transfected NIH3T3 cells and Burkitt lymphoma cells (DG75) demonstrated that PAX5-ELN was localized in the nucleus. 17179230

2007

Entrez Id: 613
Gene Symbol: BCR
BCR
CUI: C0006413
Disease: Burkitt Lymphoma
Burkitt Lymphoma
0.340 FusionGene ORPHANET Simultaneous occurrence of ETV6-RUNX1 and BCR-ABL1 (e1a2) transcripts in a child with B-cell acute lymphoblastic leukemia. 23491079

2013

Entrez Id: 25
Gene Symbol: ABL1
ABL1
CUI: C0006413
Disease: Burkitt Lymphoma
Burkitt Lymphoma
0.320 FusionGene ORPHANET Simultaneous occurrence of ETV6-RUNX1 and BCR-ABL1 (e1a2) transcripts in a child with B-cell acute lymphoblastic leukemia. 23491079

2013

Entrez Id: 4297
Gene Symbol: KMT2A
KMT2A
CUI: C0006413
Disease: Burkitt Lymphoma
Burkitt Lymphoma
0.320 FusionGene ORPHANET

Entrez Id: 861
Gene Symbol: RUNX1
RUNX1
CUI: C0006413
Disease: Burkitt Lymphoma
Burkitt Lymphoma
0.310 FusionGene ORPHANET Simultaneous occurrence of ETV6-RUNX1 and BCR-ABL1 (e1a2) transcripts in a child with B-cell acute lymphoblastic leukemia. 23491079

2013

Entrez Id: 5156
Gene Symbol: PDGFRA
PDGFRA
CUI: C0006413
Disease: Burkitt Lymphoma
Burkitt Lymphoma
0.300 FusionGene ORPHANET Therapy-related acute myeloid leukemia with eosinophilia, basophilia, t(4;14)(q12;q24) and PDGFRA rearrangement: a case report and review of the literature. 26191303

2015

Entrez Id: 3107
Gene Symbol: HLA-C
HLA-C
CUI: C0006413
Disease: Burkitt Lymphoma
Burkitt Lymphoma
0.300 SusceptibilityMutation ORPHANET KIR ligand C2 is associated with increased susceptibility to childhood ALL and confers an elevated risk for late relapse. 25163702

2014

Entrez Id: 2625
Gene Symbol: GATA3
GATA3
CUI: C0006413
Disease: Burkitt Lymphoma
Burkitt Lymphoma
0.300 SusceptibilityMutation ORPHANET Inherited GATA3 variants are associated with Ph-like childhood acute lymphoblastic leukemia and risk of relapse. 24141364

2013

Entrez Id: 2625
Gene Symbol: GATA3
GATA3
CUI: C0006413
Disease: Burkitt Lymphoma
Burkitt Lymphoma
0.300 SusceptibilityMutation ORPHANET GATA3 risk alleles are associated with ancestral components in Hispanic children with ALL. 24203929

2013

Entrez Id: 5305
Gene Symbol: PIP4K2A
PIP4K2A
CUI: C0006413
Disease: Burkitt Lymphoma
Burkitt Lymphoma
0.300 SusceptibilityMutation ORPHANET Variation at 10p12.2 and 10p14 influences risk of childhood B-cell acute lymphoblastic leukemia and phenotype. 23996088

2013

Entrez Id: 10320
Gene Symbol: IKZF1
IKZF1
CUI: C0006413
Disease: Burkitt Lymphoma
Burkitt Lymphoma
0.300 Biomarker ORPHANET High frequency of IKZF1 genetic alterations in adult patients with B-cell acute lymphoblastic leukemia. 23751147

2013

Entrez Id: 2120
Gene Symbol: ETV6
ETV6
CUI: C0006413
Disease: Burkitt Lymphoma
Burkitt Lymphoma
0.300 FusionGene ORPHANET Simultaneous occurrence of ETV6-RUNX1 and BCR-ABL1 (e1a2) transcripts in a child with B-cell acute lymphoblastic leukemia. 23491079

2013

Entrez Id: 2625
Gene Symbol: GATA3
GATA3
CUI: C0006413
Disease: Burkitt Lymphoma
Burkitt Lymphoma
0.300 SusceptibilityMutation ORPHANET Variation at 10p12.2 and 10p14 influences risk of childhood B-cell acute lymphoblastic leukemia and phenotype. 23996088

2013

Entrez Id: 26053
Gene Symbol: AUTS2
AUTS2
CUI: C0006413
Disease: Burkitt Lymphoma
Burkitt Lymphoma
0.300 FusionGene ORPHANET PAX5-AUTS2: a recurrent fusion gene in childhood B-cell precursor acute lymphoblastic leukemia. 22578776

2012

Entrez Id: 5156
Gene Symbol: PDGFRA
PDGFRA
CUI: C0006413
Disease: Burkitt Lymphoma
Burkitt Lymphoma
0.300 FusionGene ORPHANET PDGFRA rearrangement leading to hyper-eosinophilia, T-lymphoblastic lymphoma, myeloproliferative neoplasm and precursor B-cell acute lymphoblastic leukemia. 21304535

2011

Entrez Id: 27086
Gene Symbol: FOXP1
FOXP1
CUI: C0006413
Disease: Burkitt Lymphoma
Burkitt Lymphoma
0.300 FusionGene ORPHANET FOXP1 and PAX5 are rare but recurrent translocations partners in acute lymphoblastic leukemia. 21962897

2011