Source: ALL

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 673
Gene Symbol: BRAF
BRAF
B-Raf proto-oncogene, serine/threonine kinase 0.352 0.793 1.00
CUI: C0025202
Disease: melanoma
melanoma
disease 1.000 0.972 1228 31 1986 2018
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
cyclin dependent kinase inhibitor 2A 0.321 0.828 0.38
CUI: C0025202
Disease: melanoma
melanoma
disease 0.800 strong 0.940 517 24 1994 2018
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
phosphatase and tensin homolog 0.334 0.828 0.82
CUI: C0025202
Disease: melanoma
melanoma
disease 0.800 0.954 89 4 1997 2017
Entrez Id: 4893
Gene Symbol: NRAS
NRAS
NRAS proto-oncogene, GTPase 0.420 0.690 0.53
CUI: C0025202
Disease: melanoma
melanoma
disease 0.700 0.956 273 10 1988 2018
Entrez Id: 4286
Gene Symbol: MITF
MITF
melanogenesis associated transcription factor 0.526 0.690 1.00
CUI: C0025202
Disease: melanoma
melanoma
disease 0.700 0.969 164 6 1996 2018
Entrez Id: 1019
Gene Symbol: CDK4
CDK4
cyclin dependent kinase 4 0.449 0.724 7.8E-02
CUI: C0025202
Disease: melanoma
melanoma
disease 0.700 strong 0.957 117 3 1994 2018
Entrez Id: 5604
Gene Symbol: MAP2K1
MAP2K1
mitogen-activated protein kinase kinase 1 0.459 0.759 0.91
CUI: C0025202
Disease: melanoma
melanoma
disease 0.700 0.893 35 15 2003 2018
Entrez Id: 2776
Gene Symbol: GNAQ
GNAQ
G protein subunit alpha q 0.586 0.483 1.00
CUI: C0025202
Disease: melanoma
melanoma
disease 0.700 1.000 25 1 1989 2016
Entrez Id: 8314
Gene Symbol: BAP1
BAP1
BRCA1 associated protein 1 0.488 0.586 0.99
CUI: C0025202
Disease: melanoma
melanoma
disease 0.700 strong 0.913 23 0 2010 2017
Entrez Id: 2767
Gene Symbol: GNA11
GNA11
G protein subunit alpha 11 0.609 0.586 1.00
CUI: C0025202
Disease: melanoma
melanoma
disease 0.700 1.000 22 1 1989 2016
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
HRas proto-oncogene, GTPase 0.404 0.828 8.7E-02
CUI: C0025202
Disease: melanoma
melanoma
disease 0.700 1.000 17 2 1984 2015
Entrez Id: 5879
Gene Symbol: RAC1
RAC1
Rac family small GTPase 1 0.470 0.931 0.71
CUI: C0025202
Disease: melanoma
melanoma
disease 0.700 1.000 14 1 2004 2017
Entrez Id: 2066
Gene Symbol: ERBB4
ERBB4
erb-b2 receptor tyrosine kinase 4 0.494 0.690 1.00
CUI: C0025202
Disease: melanoma
melanoma
disease 0.700 0.917 12 6 2009 2016
Entrez Id: 6794
Gene Symbol: STK11
STK11
serine/threonine kinase 11 0.467 0.655 0.99
CUI: C0025202
Disease: melanoma
melanoma
disease 0.700 1.000 12 3 1999 2017
Entrez Id: 5605
Gene Symbol: MAP2K2
MAP2K2
mitogen-activated protein kinase kinase 2 0.559 0.586 0.97
CUI: C0025202
Disease: melanoma
melanoma
disease 0.660 1.000 8 5 2011 2015
Entrez Id: 7157
Gene Symbol: TP53
TP53
tumor protein p53 0.251 0.897 0.17
CUI: C0025202
Disease: melanoma
melanoma
disease 0.600 0.940 224 8 1991 2018
Entrez Id: 4763
Gene Symbol: NF1
NF1
neurofibromin 1 0.458 0.724 1.00
CUI: C0025202
Disease: melanoma
melanoma
disease 0.600 1.000 15 0 1993 2017
Entrez Id: 5537
Gene Symbol: PPP6C
PPP6C
protein phosphatase 6 catalytic subunit 0.743 0.172 0.85
CUI: C0025202
Disease: melanoma
melanoma
disease 0.540 1.000 4 0 2012 2015
Entrez Id: 8295
Gene Symbol: TRRAP
TRRAP
transformation/transcription domain associated protein 0.713 0.345 1.00
CUI: C0025202
Disease: melanoma
melanoma
disease 0.510 1.000 1 1 2011 2011
Entrez Id: 7299
Gene Symbol: TYR
TYR
tyrosinase 0.505 0.724 4.3E-32
CUI: C0025202
Disease: melanoma
melanoma
disease 0.500 0.965 239 4 1985 2018
Entrez Id: 4157
Gene Symbol: MC1R
MC1R
melanocortin 1 receptor 0.570 0.586 6.6E-11
CUI: C0025202
Disease: melanoma
melanoma
disease 0.500 0.959 151 13 1997 2018
Entrez Id: 3815
Gene Symbol: KIT
KIT
KIT proto-oncogene receptor tyrosine kinase 0.394 0.759 0.99
CUI: C0025202
Disease: melanoma
melanoma
disease 0.500 0.978 119 22 1992 2018
Entrez Id: 5894
Gene Symbol: RAF1
RAF1
Raf-1 proto-oncogene, serine/threonine kinase 0.462 0.793 0.89
CUI: C0025202
Disease: melanoma
melanoma
disease 0.500 1.000 82 3 2003 2017
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha 0.341 0.897 1.00
CUI: C0025202
Disease: melanoma
melanoma
disease 0.500 0.970 68 3 2006 2018
Entrez Id: 207
Gene Symbol: AKT1
AKT1
AKT serine/threonine kinase 1 0.355 0.862 0.98
CUI: C0025202
Disease: melanoma
melanoma
disease 0.500 0.984 65 3 2002 2018