Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 27185
Gene Symbol: DISC1
DISC1
Other specified types of schizophrenia, unspecified
0.200 Biomarker MGD Missense mutation in DISC1 C-terminal coiled-coil has GSK3β signaling and sex-dependent behavioral effects in mice. 26728762

2016

Entrez Id: 85358
Gene Symbol: SHANK3
SHANK3
Other specified types of schizophrenia, unspecified
0.200 Biomarker MGD Mice with Shank3 Mutations Associated with ASD and Schizophrenia Display Both Shared and Distinct Defects. 26687841

2016

Entrez Id: 27185
Gene Symbol: DISC1
DISC1
Other specified types of schizophrenia, unspecified
0.200 Biomarker MGD Inhibition of protein translation by the DISC1-Boymaw fusion gene from a Scottish family with major psychiatric disorders. 24908665

2015

Entrez Id: 84062
Gene Symbol: DTNBP1
DTNBP1
Other specified types of schizophrenia, unspecified
0.200 Biomarker MGD Constant light uncovers behavioral effects of a mutation in the schizophrenia risk gene Dtnbp1 in mice. 25677649

2015

Entrez Id: 5649
Gene Symbol: RELN
RELN
Other specified types of schizophrenia, unspecified
0.200 Biomarker MGD Gene-environment interaction of reelin and stress in cognitive behaviours in mice: Implications for schizophrenia. 25845740

2015

Entrez Id: 25925
Gene Symbol: ZNF521
ZNF521
Other specified types of schizophrenia, unspecified
0.200 Biomarker MGD Abnormal behaviors and developmental disorder of hippocampus in zinc finger protein 521 (ZFP521) mutant mice. 24676388

2014

Entrez Id: 64478
Gene Symbol: CSMD1
CSMD1
Other specified types of schizophrenia, unspecified
0.200 Biomarker MGD Neuropsychological deficits in mice depleted of the schizophrenia susceptibility gene CSMD1. 24244513

2014

Entrez Id: 1139
Gene Symbol: CHRNA7
CHRNA7
Other specified types of schizophrenia, unspecified
0.200 Biomarker MGD Cortical parvalbumin GABAergic deficits with α7 nicotinic acetylcholine receptor deletion: implications for schizophrenia. 24983521

2014

Entrez Id: 4135
Gene Symbol: MAP6
MAP6
Other specified types of schizophrenia, unspecified
0.200 Biomarker MGD Reduced expression of STOP/MAP6 in mice leads to cognitive deficits. 23002183

2013

Entrez Id: 5609
Gene Symbol: MAP2K7
MAP2K7
Other specified types of schizophrenia, unspecified
0.200 Biomarker MGD Converging evidence that sequence variations in the novel candidate gene MAP2K7 (MKK7) are functionally associated with schizophrenia. 22899651

2013

Entrez Id: 84062
Gene Symbol: DTNBP1
DTNBP1
Other specified types of schizophrenia, unspecified
0.200 Biomarker MGD Loss of dysbindin-1 in mice impairs reward-based operant learning by increasing impulsive and compulsive behavior. 23261874

2013

Entrez Id: 6529
Gene Symbol: SLC6A1
SLC6A1
Other specified types of schizophrenia, unspecified
0.200 Biomarker MGD GABA transporter-1 deficiency confers schizophrenia-like behavioral phenotypes. 23922840

2013

Entrez Id: 9901
Gene Symbol: SRGAP3
SRGAP3
Other specified types of schizophrenia, unspecified
0.200 Biomarker MGD Srgap3⁻/⁻ mice present a neurodevelopmental disorder with schizophrenia-related intermediate phenotypes. 22820399

2013

Entrez Id: 7534
Gene Symbol: YWHAZ
YWHAZ
Other specified types of schizophrenia, unspecified
0.200 Biomarker MGD Neurodevelopmental and neuropsychiatric behaviour defects arise from 14-3-3ζ deficiency. 22124272

2012

Entrez Id: 6671
Gene Symbol: SP4
SP4
Other specified types of schizophrenia, unspecified
0.200 Biomarker MGD Reduced NMDAR1 expression in the Sp4 hypomorphic mouse may contribute to endophenotypes of human psychiatric disorders. 20634195

2011

Entrez Id: 347730
Gene Symbol: LRRTM1
LRRTM1
Other specified types of schizophrenia, unspecified
0.200 Biomarker MGD Impaired cognitive function and altered hippocampal synapse morphology in mice lacking Lrrtm1, a gene associated with schizophrenia. 21818371

2011

Entrez Id: 10814
Gene Symbol: CPLX2
CPLX2
Other specified types of schizophrenia, unspecified
0.200 Biomarker MGD Complexin2 null mutation requires a 'second hit' for induction of phenotypic changes relevant to schizophrenia. 20412316

2010

Entrez Id: 1139
Gene Symbol: CHRNA7
CHRNA7
Other specified types of schizophrenia, unspecified
0.200 Biomarker MGD Olfactory discrimination varies in mice with different levels of α7-nicotinic acetylcholine receptor expression. 20713028

2010

Entrez Id: 63826
Gene Symbol: SRR
SRR
Other specified types of schizophrenia, unspecified
0.200 Biomarker MGD Targeted disruption of serine racemase affects glutamatergic neurotransmission and behavior. 19065142

2009

Entrez Id: 8831
Gene Symbol: SYNGAP1
SYNGAP1
Other specified types of schizophrenia, unspecified
0.200 Biomarker MGD Reduced expression of the NMDA receptor-interacting protein SynGAP causes behavioral abnormalities that model symptoms of Schizophrenia. 19145222

2009

Entrez Id: 63826
Gene Symbol: SRR
SRR
Other specified types of schizophrenia, unspecified
0.200 Biomarker MGD Serine racemase is associated with schizophrenia susceptibility in humans and in a mouse model. 19483194

2009

Entrez Id: 4192
Gene Symbol: MDK
MDK
Other specified types of schizophrenia, unspecified
0.200 Biomarker MGD Dopaminergic hypofunctions and prepulse inhibition deficits in mice lacking midkine. 19217924

2009

Entrez Id: 9378
Gene Symbol: NRXN1
NRXN1
Other specified types of schizophrenia, unspecified
0.200 Biomarker MGD Mouse neurexin-1alpha deletion causes correlated electrophysiological and behavioral changes consistent with cognitive impairments. 19822762

2009

Entrez Id: 84062
Gene Symbol: DTNBP1
DTNBP1
Other specified types of schizophrenia, unspecified
0.200 Biomarker MGD Behavioral characterization of dysbindin-1 deficient sandy mice. 18984010

2009

Entrez Id: 23621
Gene Symbol: BACE1
BACE1
Other specified types of schizophrenia, unspecified
0.200 Biomarker MGD Alteration of BACE1-dependent NRG1/ErbB4 signaling and schizophrenia-like phenotypes in BACE1-null mice. 18385378

2008