×
Entrez Id:
80204
Gene Symbol:
FBXO11
FBXO11
Otitis Media
0.220
Biomarker
MGD
A hearing and vestibular phenotyping pipeline to identify mouse mutants with hearing impairment.
20057387
2010
×
Entrez Id:
80204
Gene Symbol:
FBXO11
FBXO11
Otitis Media
0.220
Biomarker
MGD
A mutation in the F-box gene, Fbxo11 , causes otitis media in the Jeff mouse.
17035249
2006
×
Entrez Id:
51297
Gene Symbol:
BPIFA1
BPIFA1
Otitis Media
0.210
Biomarker
MGD
From these observations, we conclude that loss of Splunc1 predisposes mice to the development of otitis media .
25765466
2015
×
Entrez Id:
7050
Gene Symbol:
TGIF1
TGIF1
Otitis Media
0.210
Biomarker
MGD
Otitis media in the Tgif knockout mouse implicates TGFβ signalling in chronic middle ear inflammatory disease.
23459932
2013
×
Entrez Id:
51297
Gene Symbol:
BPIFA1
BPIFA1
Otitis Media
0.210
Biomarker
MGD
SPLUNC1/BPIFA1 contributes to pulmonary host defense against Klebsiella pneumoniae respiratory infection.
23499554
2013
SH3PXD2B
Otitis Media
0.210
Biomarker
MGD
Anterior segment dysgenesis and early-onset glaucoma in nee mice with mutation of Sh3pxd2b.
21282566
2011
×
Entrez Id:
6169
Gene Symbol:
RPL38
RPL38
Otitis Media
0.210
Biomarker
MGD
Together, these data present a previously uncharacterized combination of interrelated middle ear pathologies and suggest Rpl38 deficiency as a model to dissect the causative relationships between neo-ossification, cholesterol crystal deposition, and Eustachian tubes in the etiology of otitis media .
21062742
2011
SH3PXD2B
Otitis Media
0.210
Biomarker
MGD
The podosomal-adaptor protein SH3PXD2B is essential for normal postnatal development.
19669234
2009
×
Entrez Id:
6169
Gene Symbol:
RPL38
RPL38
Otitis Media
0.210
Biomarker
MGD
Fetal erythropoiesis and hemoglobin ontogeny in tail-short (Ts/+) mutant mice.
465735
1979
×
Entrez Id:
5167
Gene Symbol:
ENPP1
ENPP1
Otitis Media
0.200
Biomarker
MGD
Ectopic calcification in pseudoxanthoma elasticum responds to inhibition of tissue-nonspecific alkaline phosphatase.
28592560
2017
×
Entrez Id:
5167
Gene Symbol:
ENPP1
ENPP1
Otitis Media
0.200
Biomarker
MGD
Here, we report on otitis media -related hearing loss in asj (ages with stiffened joints) mutant mice, which bear a point mutation in the Enpp1 gene.
27959908
2016
×
Entrez Id:
5167
Gene Symbol:
ENPP1
ENPP1
Otitis Media
0.200
Biomarker
MGD
Spontaneous asj-2J mutant mouse as a model for generalized arterial calcification of infancy: a large deletion/insertion mutation in the Enpp1 gene.
25479107
2014
×
Entrez Id:
5167
Gene Symbol:
ENPP1
ENPP1
Otitis Media
0.200
Biomarker
MGD
Mutant Enpp1asj mice as a model for generalized arterial calcification of infancy.
23798568
2013
×
Entrez Id:
4000
Gene Symbol:
LMNA
LMNA
Otitis Media
0.200
Biomarker
MGD
Pathological features in the LmnaDhe/+ mutant mouse provide a novel model of human otitis media and laminopathies.
22819531
2012
×
Entrez Id:
4000
Gene Symbol:
LMNA
LMNA
Otitis Media
0.200
Biomarker
MGD
Mitotic defects lead to pervasive aneuploidy and accompany loss of RB1 activity in mouse LmnaDhe dermal fibroblasts.
21464947
2011
×
Entrez Id:
7161
Gene Symbol:
TP73
TP73
Otitis Media
0.200
Biomarker
MGD
microRNA-34a regulates neurite outgrowth, spinal morphology, and function.
22160706
2011
×
Entrez Id:
25776
Gene Symbol:
CBY1
CBY1
Otitis Media
0.200
Biomarker
MGD
Altered lung morphogenesis, epithelial cell differentiation and mechanics in mice deficient in the Wnt/β-catenin antagonist Chibby.
21049041
2010
×
Entrez Id:
2122
Gene Symbol:
MECOM
MECOM
Otitis Media
0.200
Biomarker
MGD
A hearing and vestibular phenotyping pipeline to identify mouse mutants with hearing impairment.
20057387
2010
×
Entrez Id:
4000
Gene Symbol:
LMNA
LMNA
Otitis Media
0.200
Biomarker
MGD
Disheveled hair and ear (Dhe), a spontaneous mouse Lmna mutation modeling human laminopathies.
20376364
2010
×
Entrez Id:
25776
Gene Symbol:
CBY1
CBY1
Otitis Media
0.200
Biomarker
MGD
Inactivation of Chibby affects function of motile airway cilia.
19364920
2009
×
Entrez Id:
5251
Gene Symbol:
PHEX
PHEX
Otitis Media
0.200
Biomarker
MGD
A mouse model with postnatal endolymphatic hydrops and hearing loss.
18289812
2008
×
Entrez Id:
2070
Gene Symbol:
EYA4
EYA4
Otitis Media
0.200
Biomarker
MGD
We suggest that some human otitis media susceptibility reflects underlying genetic predisposition in genes like EYA4 that regulate middle ear and eustachian tube anatomy.
18219393
2008
×
Entrez Id:
57167
Gene Symbol:
SALL4
SALL4
Otitis Media
0.200
Biomarker
MGD
A Sall4 mutant mouse model useful for studying the role of Sall4 in early embryonic development and organogenesis.
17216607
2007
×
Entrez Id:
3425
Gene Symbol:
IDUA
IDUA
Otitis Media
0.200
Biomarker
MGD
Age-related functional and histopathological changes of the ear in the MPS I mouse.
17101178
2007
×
Entrez Id:
4669
Gene Symbol:
NAGLU
NAGLU
Otitis Media
0.200
Biomarker
MGD
Development of sensory, motor and behavioral deficits in the murine model of Sanfilippo syndrome type B.
17712420
2007