Source: BEFREE

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 6794
Gene Symbol: STK11
STK11
serine/threonine kinase 11 0.467 0.655 0.99
CUI: C0029925
Disease: Ovarian Carcinoma
Ovarian Carcinoma
disease 0.560 1.000 6 0 1999 2016
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
BRCA2, DNA repair associated 0.426 0.793 5.5E-24
CUI: C0029925
Disease: Ovarian Carcinoma
Ovarian Carcinoma
disease 0.500 0.942 667 10 1994 2018
Entrez Id: 83990
Gene Symbol: BRIP1
BRIP1
BRCA1 interacting protein C-terminal helicase 1 0.586 0.552 4.8E-17
CUI: C0029925
Disease: Ovarian Carcinoma
Ovarian Carcinoma
disease 0.470 1.000 7 2 2006 2016
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
BRCA1, DNA repair associated 0.410 0.862 1.8E-28
CUI: C0029925
Disease: Ovarian Carcinoma
Ovarian Carcinoma
disease 0.400 0.946 1237 26 1992 2018
Entrez Id: 7157
Gene Symbol: TP53
TP53
tumor protein p53 0.251 0.897 0.17
CUI: C0029925
Disease: Ovarian Carcinoma
Ovarian Carcinoma
disease 0.400 0.950 298 4 1991 2018
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
erb-b2 receptor tyrosine kinase 2 0.352 0.862 1.8E-03
CUI: C0029925
Disease: Ovarian Carcinoma
Ovarian Carcinoma
disease 0.400 0.973 188 2 1989 2018
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha 0.341 0.897 1.00
CUI: C0029925
Disease: Ovarian Carcinoma
Ovarian Carcinoma
disease 0.400 0.962 78 2 1999 2018
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
estrogen receptor 1 0.355 0.897 1.00
CUI: C0029925
Disease: Ovarian Carcinoma
Ovarian Carcinoma
disease 0.400 0.926 68 1 1990 2018
Entrez Id: 207
Gene Symbol: AKT1
AKT1
AKT serine/threonine kinase 1 0.355 0.862 0.98
CUI: C0029925
Disease: Ovarian Carcinoma
Ovarian Carcinoma
disease 0.400 0.979 48 1 1997 2016
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
phosphatase and tensin homolog 0.334 0.828 0.82
CUI: C0029925
Disease: Ovarian Carcinoma
Ovarian Carcinoma
disease 0.400 0.914 35 1 1998 2018
Entrez Id: 4292
Gene Symbol: MLH1
MLH1
mutL homolog 1 0.424 0.759 5.1E-05
CUI: C0029925
Disease: Ovarian Carcinoma
Ovarian Carcinoma
disease 0.400 1.000 31 2 1995 2016
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
KRAS proto-oncogene, GTPase 0.350 0.724 9.0E-04
CUI: C0029925
Disease: Ovarian Carcinoma
Ovarian Carcinoma
disease 0.400 0.917 24 1 1993 2017
Entrez Id: 580
Gene Symbol: BARD1
BARD1
BRCA1 associated RING domain 1 0.624 0.379 2.2E-24
CUI: C0029925
Disease: Ovarian Carcinoma
Ovarian Carcinoma
disease 0.400 0.870 23 1 2001 2018
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
mutS homolog 2 0.437 0.690 0.91
CUI: C0029925
Disease: Ovarian Carcinoma
Ovarian Carcinoma
disease 0.400 0.947 19 1 1994 2014
Entrez Id: 673
Gene Symbol: BRAF
BRAF
B-Raf proto-oncogene, serine/threonine kinase 0.352 0.793 1.00
CUI: C0029925
Disease: Ovarian Carcinoma
Ovarian Carcinoma
disease 0.400 0.944 18 2 2003 2017
Entrez Id: 898
Gene Symbol: CCNE1
CCNE1
cyclin E1 0.590 0.517 0.96
CUI: C0029925
Disease: Ovarian Carcinoma
Ovarian Carcinoma
disease 0.400 1.000 13 2 2008 2018
Entrez Id: 208
Gene Symbol: AKT2
AKT2
AKT serine/threonine kinase 2 0.512 0.655 0.61
CUI: C0029925
Disease: Ovarian Carcinoma
Ovarian Carcinoma
disease 0.400 1.000 11 1 1992 2016
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
partner and localizer of BRCA2 0.569 0.552 7.3E-20
CUI: C0029925
Disease: Ovarian Carcinoma
Ovarian Carcinoma
disease 0.390 0.778 9 2 2008 2015
Entrez Id: 472
Gene Symbol: ATM
ATM
ATM serine/threonine kinase 0.401 0.862 6.0E-46
CUI: C0029925
Disease: Ovarian Carcinoma
Ovarian Carcinoma
disease 0.380 1.000 8 1 2003 2018
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2
checkpoint kinase 2 0.494 0.621 1.2E-23
CUI: C0029925
Disease: Ovarian Carcinoma
Ovarian Carcinoma
disease 0.380 0.875 8 4 2004 2016
Entrez Id: 999
Gene Symbol: CDH1
CDH1
cadherin 1 0.432 0.759 0.11
CUI: C0029925
Disease: Ovarian Carcinoma
Ovarian Carcinoma
disease 0.370 1.000 7 0 1994 2016
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
catenin beta 1 0.417 0.759 1.00
CUI: C0029925
Disease: Ovarian Carcinoma
Ovarian Carcinoma
disease 0.360 1.000 6 1 1998 2014
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
mutS homolog 6 0.495 0.586 2.2E-05
CUI: C0029925
Disease: Ovarian Carcinoma
Ovarian Carcinoma
disease 0.350 1.000 5 0 2006 2015
Entrez Id: 5395
Gene Symbol: PMS2
PMS2
PMS1 homolog 2, mismatch repair system component 0.526 0.586 1.2E-27
CUI: C0029925
Disease: Ovarian Carcinoma
Ovarian Carcinoma
disease 0.350 1.000 5 2 2006 2016
Entrez Id: 545
Gene Symbol: ATR
ATR
ATR serine/threonine kinase 0.486 0.759 1.7E-08
CUI: C0029925
Disease: Ovarian Carcinoma
Ovarian Carcinoma
disease 0.340 1.000 4 0 2006 2015