Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53
tumor protein p53 0.251 0.897 0.17
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
phenotype 0.100 0.937 237 4 1991 2018
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
epidermal growth factor receptor 0.325 0.862 0.50
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
phenotype 0.100 0.921 89 3 1992 2018
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
vascular endothelial growth factor A 0.298 0.897 2.7E-05
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
phenotype 0.100 0.976 83 0 1995 2018
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
hypoxia inducible factor 1 subunit alpha 0.367 0.793 0.97
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
phenotype 0.100 1.000 71 2 2000 2018
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
erb-b2 receptor tyrosine kinase 2 0.352 0.862 1.8E-03
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
phenotype 0.100 0.939 66 0 1989 2016
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
cyclin dependent kinase inhibitor 2A 0.321 0.828 0.38
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
phenotype 0.100 0.873 55 0 1995 2015
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
prostaglandin-endoperoxide synthase 2 0.338 0.897 1.00
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
phenotype 0.100 0.981 53 0 1999 2017
Entrez Id: 6696
Gene Symbol: SPP1
SPP1
secreted phosphoprotein 1 0.391 0.862 1.0E-06
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
phenotype 0.100 0.953 43 0 2002 2018
Entrez Id: 367
Gene Symbol: AR
AR
androgen receptor 0.380 0.793 0.98
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
phenotype 0.100 0.972 36 1 1994 2017
Entrez Id: 960
Gene Symbol: CD44
CD44
CD44 molecule (Indian blood group) 0.389 0.862 2.1E-07
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
phenotype 0.100 0.944 36 0 1995 2017
Entrez Id: 596
Gene Symbol: BCL2
BCL2
BCL2, apoptosis regulator 0.312 0.862 0.57
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
phenotype 0.100 0.914 35 0 1993 2017
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
signal transducer and activator of transcription 3 0.358 0.862 1.00
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
phenotype 0.100 1.000 35 0 2002 2018
Entrez Id: 4609
Gene Symbol: MYC
MYC
MYC proto-oncogene, bHLH transcription factor 0.382 0.724 1.00
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
phenotype 0.100 1.000 33 0 1989 2016
Entrez Id: 3569
Gene Symbol: IL6
IL6
interleukin 6 0.287 0.966 0.34
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
phenotype 0.100 1.000 32 0 1992 2018
Entrez Id: 2146
Gene Symbol: EZH2
EZH2
enhancer of zeste 2 polycomb repressive complex 2 subunit 0.421 0.759 1.00
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
phenotype 0.100 0.933 30 0 2007 2018
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
estrogen receptor 1 0.355 0.897 1.00
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
phenotype 0.100 0.889 27 0 1994 2016
Entrez Id: 673
Gene Symbol: BRAF
BRAF
B-Raf proto-oncogene, serine/threonine kinase 0.352 0.793 1.00
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
phenotype 0.100 0.962 26 1 2004 2017
Entrez Id: 4193
Gene Symbol: MDM2
MDM2
MDM2 proto-oncogene 0.396 0.759 1.00
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
phenotype 0.100 1.000 26 0 1993 2017
Entrez Id: 29072
Gene Symbol: SETD2
SETD2
SET domain containing 2 0.465 0.724 1.00
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
phenotype 0.100 1.000 26 0 2000 2016
Entrez Id: 4233
Gene Symbol: MET
MET
MET proto-oncogene, receptor tyrosine kinase 0.405 0.793 0.99
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
phenotype 0.100 0.960 25 0 1996 2017
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
matrix metallopeptidase 9 0.339 0.862 7.0E-18
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
phenotype 0.100 0.958 24 0 2002 2018
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
phosphatase and tensin homolog 0.334 0.828 0.82
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
phenotype 0.100 1.000 24 0 1999 2017
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
transforming growth factor beta 1 0.336 0.931 0.17
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
phenotype 0.100 1.000 23 0 1995 2016
Entrez Id: 1950
Gene Symbol: EGF
EGF
epidermal growth factor 0.386 0.897 1.0E-16
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
phenotype 0.100 0.955 22 0 1982 2018
Entrez Id: 7852
Gene Symbol: CXCR4
CXCR4
C-X-C motif chemokine receptor 4 0.391 0.897 1.4E-02
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
phenotype 0.100 1.000 22 1 2001 2016