Source: BEFREE

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7157
Gene Symbol: TP53
TP53
tumor protein p53 0.236 0.962 0.53
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
phenotype 0.100 None 0.960 446 6 1991 2020
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
epidermal growth factor receptor 0.295 0.885 0.37
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
phenotype 0.100 None 0.967 184 6 1992 2020
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
vascular endothelial growth factor A 0.266 0.923 2.4E-05
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
phenotype 0.100 None 0.981 160 1 1995 2020
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
hypoxia inducible factor 1 subunit alpha 0.327 0.923 0.98
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
phenotype 0.100 None 0.985 137 3 1999 2020
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
erb-b2 receptor tyrosine kinase 2 0.328 0.923 6.0E-03
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
phenotype 0.100 None 0.964 112 0 1987 2020
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
catenin beta 1 0.303 0.885 1.00
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
phenotype 0.100 None 0.982 109 0 1998 2019
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
prostaglandin-endoperoxide synthase 2 0.314 0.962 1.00
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
phenotype 0.100 None 0.970 99 0 1999 2019
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
cyclin dependent kinase inhibitor 2A 0.300 0.885 0.39
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
phenotype 0.100 None 0.926 95 1 1995 2020
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
signal transducer and activator of transcription 3 0.320 0.923 1.00
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
phenotype 0.100 None 0.989 90 0 2002 2020
Entrez Id: 960
Gene Symbol: CD44
CD44
CD44 molecule (Indian blood group) 0.363 0.962 2.4E-07
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
phenotype 0.100 None 0.964 83 0 1995 2019
Entrez Id: 367
Gene Symbol: AR
AR
androgen receptor 0.351 0.846 0.99
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
phenotype 0.100 None 0.986 74 1 1994 2020
Entrez Id: 6696
Gene Symbol: SPP1
SPP1
secreted phosphoprotein 1 0.353 0.885 2.1E-06
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
phenotype 0.100 None 0.986 70 0 2002 2019
Entrez Id: 596
Gene Symbol: BCL2
BCL2
BCL2 apoptosis regulator 0.291 0.885 0.56
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
phenotype 0.100 None 0.956 68 0 1990 2019
Entrez Id: 7852
Gene Symbol: CXCR4
CXCR4
C-X-C motif chemokine receptor 4 0.362 0.923 1.8E-02
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
phenotype 0.100 None 0.971 68 1 2000 2019
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
estrogen receptor 1 0.324 0.962 1.00
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
phenotype 0.100 None 0.909 66 0 1993 2020
Entrez Id: 3569
Gene Symbol: IL6
IL6
interleukin 6 0.248 0.962 0.32
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
phenotype 0.100 None 1.000 66 0 1992 2020
Entrez Id: 207
Gene Symbol: AKT1
AKT1
AKT serine/threonine kinase 1 0.311 0.962 0.98
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
phenotype 0.100 None 0.984 63 0 2002 2020
Entrez Id: 4609
Gene Symbol: MYC
MYC
MYC proto-oncogene, bHLH transcription factor 0.344 0.923 1.00
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
phenotype 0.100 None 0.984 62 0 1989 2019
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
transforming growth factor beta 1 0.287 0.962 3.7E-02
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
phenotype 0.100 None 0.967 61 1 1994 2019
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha 0.292 0.923 1.00
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
phenotype 0.100 None 1.000 59 1 2005 2020
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma 0.320 0.885 1.4E-06
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
phenotype 0.100 None 1.000 54 1 2005 2020
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
phosphatase and tensin homolog 0.305 0.923 0.26
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
phenotype 0.100 None 0.981 54 1 1998 2020
Entrez Id: 4233
Gene Symbol: MET
MET
MET proto-oncogene, receptor tyrosine kinase 0.380 0.846 0.97
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
phenotype 0.100 None 0.981 52 0 1995 2019
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta 0.322 0.885 1.00
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
phenotype 0.100 None 1.000 51 1 2005 2020
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta 0.319 0.885 1.00
CUI: C0178874
Disease: Tumor Progression
Tumor Progression
phenotype 0.100 None 1.000 51 0 2005 2020