×
Entrez Id: 673
Gene Symbol: BRAF
BRAF
Papillary thyroid carcinoma
0.900
SomaticCausalMutation
ORPHANET
Follicular variant of papillary thyroid carcinoma (FVPTC): histological features, BRAF V600E mutation, and lymph node status.
25702102 2015
×
Entrez Id: 673
Gene Symbol: BRAF
BRAF
Papillary thyroid carcinoma
0.900
SomaticCausalMutation
ORPHANET
The frequencies of a positive BRAF (V600E) mutation by real-time PCR, positive BRAF V600E IHC, and high BRAF RNA ISH were 84%, 86%, and 70%, respectively, in PTC .
25468810 2015
×
Entrez Id: 673
Gene Symbol: BRAF
BRAF
Papillary thyroid carcinoma
0.900
SomaticCausalMutation
ORPHANET
Pax-8-PPAR-γ fusion protein in thyroid carcinoma.
25069464 2014
×
Entrez Id: 673
Gene Symbol: BRAF
BRAF
Papillary thyroid carcinoma
0.900
SomaticCausalMutation
ORPHANET
BRAF mutation correlates with recurrent papillary thyroid carcinoma in Chinese patients.25489262 2014
×
Entrez Id: 673
Gene Symbol: BRAF
BRAF
Papillary thyroid carcinoma
0.900
SomaticCausalMutation
ORPHANET
Molecular genetics of papillary thyroid carcinoma: great expectations.
17891228 2007
×
Entrez Id: 673
Gene Symbol: BRAF
BRAF
Papillary thyroid carcinoma
0.900
SomaticCausalMutation
ORPHANET
Moreover, there was no overlap between PTC with RET/PTC , BRAF , or RAS mutations, which altogether were present in 66% of cases.
12670889 2003
×
Entrez Id: 7080
Gene Symbol: NKX2-1
NKX2-1
Papillary thyroid carcinoma
0.700
SusceptibilityMutation
ORPHANET
Both FOXE1 and NKX2-1 were associated with the increased risk of sporadic Japanese PTC .
21730105 2011
×
Entrez Id: 5979
Gene Symbol: RET
RET
Papillary thyroid carcinoma
0.600
FusionGene
ORPHANET
Our data reveal that both multiplex qPCR and FISH assays are equally applicable for detection of RET /PTC rearrangements.
25407564 2015
×
Entrez Id: 8030
Gene Symbol: CCDC6
CCDC6
Papillary thyroid carcinoma
0.600
FusionGene
ORPHANET
Among 73 PTC patients with sufficient tissue available for FISH and multiplex qPCR, 10 cases were defined as RET/PTC positive by both assays, including eight CCDC6 /RET and two NCOA4/RET fusions with relatively high RET mRNA.
25407564 2015
×
Entrez Id: 5979
Gene Symbol: RET
RET
Papillary thyroid carcinoma
0.600
FusionGene
ORPHANET
Molecular genetics of papillary thyroid carcinoma: great expectations.
17891228 2007
×
Entrez Id: 2304
Gene Symbol: FOXE1
FOXE1
Papillary thyroid carcinoma
0.500
SusceptibilityMutation
ORPHANET
Both FOXE1 and NKX2-1 were associated with the increased risk of sporadic Japanese PTC .
21730105 2011
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Papillary thyroid carcinoma
0.400
SomaticCausalMutation
ORPHANET
RAS mutations in indeterminate thyroid nodules are predictive of the follicular variant of papillary thyroid carcinoma.
25109485 2015
×
Entrez Id: 8031
Gene Symbol: NCOA4
NCOA4
Papillary thyroid carcinoma
0.400
FusionGene
ORPHANET
Among 73 PTC patients with sufficient tissue available for FISH and multiplex qPCR, 10 cases were defined as RET/PTC positive by both assays, including eight CCDC6/RET and two NCOA4 /RET fusions with relatively high RET mRNA.
25407564 2015
×
Entrez Id: 4893
Gene Symbol: NRAS
NRAS
Papillary thyroid carcinoma
0.400
SomaticCausalMutation
ORPHANET
Preoperative RAS mutational analysis is of great value in predicting follicular variant of papillary thyroid carcinoma.
25648502 2015
×
Entrez Id: 7849
Gene Symbol: PAX8
PAX8
Papillary thyroid carcinoma
0.400
FusionGene
ORPHANET
Low frequency of PAX8-PPARγ rearrangement in follicular thyroid carcinomas in Japanese patients.
25708358 2015
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Papillary thyroid carcinoma
0.400
SomaticCausalMutation
ORPHANET
Preoperative RAS mutational analysis is of great value in predicting follicular variant of papillary thyroid carcinoma.
25648502 2015
×
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
Papillary thyroid carcinoma
0.400
FusionGene
ORPHANET
Low frequency of PAX8-PPARγ rearrangement in follicular thyroid carcinomas in Japanese patients.
25708358 2015
×
Entrez Id: 4893
Gene Symbol: NRAS
NRAS
Papillary thyroid carcinoma
0.400
SomaticCausalMutation
ORPHANET
RAS mutations in indeterminate thyroid nodules are predictive of the follicular variant of papillary thyroid carcinoma.
25109485 2015
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Papillary thyroid carcinoma
0.400
SomaticCausalMutation
ORPHANET
Thyroid nodules with KRAS mutations are different from nodules with NRAS and HRAS mutations with regard to cytopathologic and histopathologic outcome characteristics.
25132659 2014
×
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
Papillary thyroid carcinoma
0.400
FusionGene
ORPHANET
The PAX8-PPARG gene fusion results in the production of a Pax-8-PPAR-γ fusion protein (PPFP), which is found in approximately one-third of follicular thyroid carcinomas, as well as some follicular-variant papillary thyroid carcinomas .
25069464 2014
×
Entrez Id: 4893
Gene Symbol: NRAS
NRAS
Papillary thyroid carcinoma
0.400
SomaticCausalMutation
ORPHANET
Thyroid nodules with KRAS mutations are different from nodules with NRAS and HRAS mutations with regard to cytopathologic and histopathologic outcome characteristics.
25132659 2014
×
Entrez Id: 7849
Gene Symbol: PAX8
PAX8
Papillary thyroid carcinoma
0.400
FusionGene
ORPHANET
The PAX8 -PPARG gene fusion results in the production of a Pax-8 -PPAR-γ fusion protein (PPFP), which is found in approximately one-third of follicular thyroid carcinomas, as well as some follicular-variant papillary thyroid carcinomas .
25069464 2014
×
Entrez Id: 729582
Gene Symbol: DIRC3
DIRC3
Papillary thyroid carcinoma
0.400
SusceptibilityMutation
ORPHANET
Genome-wide association study on differentiated thyroid cancer.
23894154 2013
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Papillary thyroid carcinoma
0.400
SomaticCausalMutation
ORPHANET
BRAF and RAS mutations in follicular variants of papillary thyroid carcinoma.
23625203 2013
×
Entrez Id: 4914
Gene Symbol: NTRK1
NTRK1
Papillary thyroid carcinoma
0.400
FusionGene
ORPHANET
Rearrangements of NTRK1 gene in papillary thyroid carcinoma .
19883730 2010