Source: BEFREE

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
KRAS proto-oncogene, GTPase 0.350 0.724 9.0E-04
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
disease 0.700 0.960 124 3 1983 2018
Entrez Id: 673
Gene Symbol: BRAF
BRAF
B-Raf proto-oncogene, serine/threonine kinase 0.352 0.793 1.00
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
disease 0.700 1.000 25 2 2002 2018
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
epidermal growth factor receptor 0.325 0.862 0.50
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
disease 0.500 0.977 690 8 1988 2018
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha 0.341 0.897 1.00
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
disease 0.500 0.971 34 1 2002 2018
Entrez Id: 8626
Gene Symbol: TP63
TP63
tumor protein p63 0.419 0.759 1.00
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
disease 0.490 1.000 9 3 2000 2016
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
BRCA2, DNA repair associated 0.426 0.793 5.5E-24
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
disease 0.450 0.800 5 2 2000 2017
Entrez Id: 7157
Gene Symbol: TP53
TP53
tumor protein p53 0.251 0.897 0.17
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
disease 0.400 0.960 400 25 1989 2018
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
erb-b2 receptor tyrosine kinase 2 0.352 0.862 1.8E-03
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
disease 0.400 0.969 65 1 1989 2018
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
phosphatase and tensin homolog 0.334 0.828 0.82
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
disease 0.400 1.000 25 1 1998 2017
Entrez Id: 2067
Gene Symbol: ERCC1
ERCC1
ERCC excision repair 1, endonuclease non-catalytic subunit 0.463 0.724 2.1E-07
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
disease 0.400 0.900 20 6 2005 2016
Entrez Id: 4915
Gene Symbol: NTRK2
NTRK2
neurotrophic receptor tyrosine kinase 2 0.514 0.586 1.00
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
disease 0.330 1.000 3 0 2013 2017
Entrez Id: 2042
Gene Symbol: EPHA3
EPHA3
EPH receptor A3 0.552 0.586 1.4E-05
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
disease 0.320 1.000 2 0 2006 2016
Entrez Id: 4916
Gene Symbol: NTRK3
NTRK3
neurotrophic receptor tyrosine kinase 3 0.547 0.586 1.00
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
disease 0.310 1.000 1 0 2017 2017
Entrez Id: 253260
Gene Symbol: RICTOR
RICTOR
RPTOR independent companion of MTOR complex 2 0.656 0.379 1.00
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
disease 0.310 1.000 1 0 2016 2016
Entrez Id: 283106
Gene Symbol: CSNK2A3
CSNK2A3
casein kinase 2 alpha 3 0.834 0.069 2.7E-10
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
disease 0.310 1.000 1 0 2010 2010
Entrez Id: 7015
Gene Symbol: TERT
TERT
telomerase reverse transcriptase 0.393 0.828 1.00
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
disease 0.200 0.976 42 7 2002 2017
Entrez Id: 1138
Gene Symbol: CHRNA5
CHRNA5
cholinergic receptor nicotinic alpha 5 subunit 0.598 0.414 1.8E-06
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
disease 0.200 0.950 40 6 2008 2016
Entrez Id: 1136
Gene Symbol: CHRNA3
CHRNA3
cholinergic receptor nicotinic alpha 3 subunit 0.584 0.448 1.2E-07
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
disease 0.200 1.000 39 13 2008 2017
Entrez Id: 2068
Gene Symbol: ERCC2
ERCC2
ERCC excision repair 2, TFIIH core complex helicase subunit 0.447 0.828 1.7E-20
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
disease 0.200 0.897 39 2 2001 2014
Entrez Id: 1548
Gene Symbol: CYP2A6
CYP2A6
cytochrome P450 family 2 subfamily A member 6 0.546 0.690 6.5E-09
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
disease 0.200 0.957 23 0 1999 2017
Entrez Id: 81037
Gene Symbol: CLPTM1L
CLPTM1L
CLPTM1 like 0.602 0.517 5.7E-05
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
disease 0.200 0.957 23 5 2008 2017
Entrez Id: 1143
Gene Symbol: CHRNB4
CHRNB4
cholinergic receptor nicotinic beta 4 subunit 0.642 0.345 9.1E-02
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
disease 0.200 1.000 18 3 2008 2016
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2
checkpoint kinase 2 0.494 0.621 1.2E-23
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
disease 0.200 1.000 10 2 2000 2014
Entrez Id: 4854
Gene Symbol: NOTCH3
NOTCH3
notch 3 0.469 0.690 0.87
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
disease 0.150 1.000 5 0 2007 2016
Entrez Id: 123688
Gene Symbol: HYKK
HYKK
hydroxylysine kinase 0.773 0.276 8.5E-06
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung
disease 0.150 1.000 5 3 2008 2013