Source: BEFREE

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 4613
Gene Symbol: MYCN
MYCN
MYCN proto-oncogene, bHLH transcription factor 0.481 0.759 0.89
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
disease 0.100 0.955 554 0 1985 2018
Entrez Id: 7157
Gene Symbol: TP53
TP53
tumor protein p53 0.251 0.897 0.17
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
disease 0.100 0.932 117 4 1988 2016
Entrez Id: 238
Gene Symbol: ALK
ALK
ALK receptor tyrosine kinase 0.448 0.724 3.5E-06
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
disease 0.100 0.925 93 5 2000 2018
Entrez Id: 351
Gene Symbol: APP
APP
amyloid beta precursor protein 0.430 0.862 6.2E-02
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
disease 0.100 0.983 58 4 1989 2016
Entrez Id: 596
Gene Symbol: BCL2
BCL2
BCL2, apoptosis regulator 0.312 0.862 0.57
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
disease 0.100 0.955 44 0 1992 2016
Entrez Id: 7054
Gene Symbol: TH
TH
tyrosine hydroxylase 0.498 0.759 2.5E-06
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
disease 0.100 0.951 41 0 1989 2013
Entrez Id: 627
Gene Symbol: BDNF
BDNF
brain derived neurotrophic factor 0.382 0.828 0.70
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
disease 0.100 0.975 40 0 1993 2016
Entrez Id: 4609
Gene Symbol: MYC
MYC
MYC proto-oncogene, bHLH transcription factor 0.382 0.724 1.00
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
disease 0.100 1.000 35 0 1985 2018
Entrez Id: 8929
Gene Symbol: PHOX2B
PHOX2B
paired like homeobox 2b 0.611 0.483 0.94
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
disease 0.100 0.943 35 1 2004 2017
Entrez Id: 841
Gene Symbol: CASP8
CASP8
caspase 8 0.443 0.793 2.8E-06
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
disease 0.100 0.941 34 1 2000 2015
Entrez Id: 4803
Gene Symbol: NGF
NGF
nerve growth factor 0.426 0.862 0.76
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
disease 0.100 0.969 32 0 1989 2016
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
vascular endothelial growth factor A 0.298 0.897 2.7E-05
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
disease 0.100 0.969 32 0 2000 2017
Entrez Id: 4914
Gene Symbol: NTRK1
NTRK1
neurotrophic receptor tyrosine kinase 1 0.443 0.759 6.8E-06
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
disease 0.100 1.000 30 1 1993 2013
Entrez Id: 5979
Gene Symbol: RET
RET
ret proto-oncogene 0.418 0.724 1.00
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
disease 0.100 0.929 28 0 1990 2016
Entrez Id: 7248
Gene Symbol: TSC1
TSC1
TSC complex subunit 1 0.403 0.759 1.00
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
disease 0.100 1.000 28 1 1994 2011
Entrez Id: 4193
Gene Symbol: MDM2
MDM2
MDM2 proto-oncogene 0.396 0.759 1.00
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
disease 0.100 0.889 27 0 1995 2014
Entrez Id: 6647
Gene Symbol: SOD1
SOD1
superoxide dismutase 1 0.406 0.931 0.13
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
disease 0.100 1.000 27 5 1988 2013
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
ATP binding cassette subfamily B member 1 0.371 0.828 1.3E-05
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
disease 0.100 0.958 24 0 1989 2014
Entrez Id: 4804
Gene Symbol: NGFR
NGFR
nerve growth factor receptor 0.508 0.724 0.30
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
disease 0.100 1.000 21 0 1987 2015
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha 0.341 0.897 1.00
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
disease 0.100 0.952 21 0 2003 2016
Entrez Id: 836
Gene Symbol: CASP3
CASP3
caspase 3 0.391 0.862 0.28
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
disease 0.100 0.900 20 0 2000 2015
Entrez Id: 7161
Gene Symbol: TP73
TP73
tumor protein p73 0.472 0.724 1.00
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
disease 0.100 1.000 20 1 1997 2016
Entrez Id: 3481
Gene Symbol: IGF2
IGF2
insulin like growth factor 2 0.399 0.828 4.7E-02
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
disease 0.100 1.000 19 0 1991 2013
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta 0.386 0.862 1.00
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
disease 0.100 0.947 19 0 2003 2016
Entrez Id: 83478
Gene Symbol: ARHGAP24
ARHGAP24
Rho GTPase activating protein 24 0.481 0.724 6.1E-10
CUI: C0700095
Disease: Central neuroblastoma
Central neuroblastoma
disease 0.100 1.000 19 2 1997 2016