Source: BEFREE

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 324
Gene Symbol: APC
APC
APC, WNT signaling pathway regulator 0.397 0.828 1.00
CUI: C1527249
Disease: Colorectal Cancer
Colorectal Cancer
disease 0.900 strong 0.942 308 6 1990 2018
Entrez Id: 4292
Gene Symbol: MLH1
MLH1
mutL homolog 1 0.424 0.759 5.1E-05
CUI: C1527249
Disease: Colorectal Cancer
Colorectal Cancer
disease 0.700 strong 0.963 383 11 1993 2018
Entrez Id: 4436
Gene Symbol: MSH2
MSH2
mutS homolog 2 0.437 0.690 0.91
CUI: C1527249
Disease: Colorectal Cancer
Colorectal Cancer
disease 0.700 strong 0.948 229 5 1993 2018
Entrez Id: 4089
Gene Symbol: SMAD4
SMAD4
SMAD family member 4 0.430 0.759 1.00
CUI: C1527249
Disease: Colorectal Cancer
Colorectal Cancer
disease 0.700 strong 0.964 55 0 1996 2018
Entrez Id: 6934
Gene Symbol: TCF7L2
TCF7L2
transcription factor 7 like 2 0.538 0.621 0.99
CUI: C1527249
Disease: Colorectal Cancer
Colorectal Cancer
disease 0.700 0.917 24 1 1999 2018
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
matrix metallopeptidase 2 0.373 0.862 0.84
CUI: C1527249
Disease: Colorectal Cancer
Colorectal Cancer
disease 0.700 1.000 13 0 2003 2018
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
KRAS proto-oncogene, GTPase 0.350 0.724 9.0E-04
CUI: C1527249
Disease: Colorectal Cancer
Colorectal Cancer
disease 0.600 0.964 477 5 1993 2018
Entrez Id: 673
Gene Symbol: BRAF
BRAF
B-Raf proto-oncogene, serine/threonine kinase 0.352 0.793 1.00
CUI: C1527249
Disease: Colorectal Cancer
Colorectal Cancer
disease 0.600 0.968 377 2 2002 2018
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha 0.341 0.897 1.00
CUI: C1527249
Disease: Colorectal Cancer
Colorectal Cancer
disease 0.600 0.988 160 0 2003 2018
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
mutS homolog 6 0.495 0.586 2.2E-05
CUI: C1527249
Disease: Colorectal Cancer
Colorectal Cancer
disease 0.600 strong 0.962 79 3 1988 2018
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
catenin beta 1 0.417 0.759 1.00
CUI: C1527249
Disease: Colorectal Cancer
Colorectal Cancer
disease 0.600 0.957 47 0 1997 2017
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
ATP binding cassette subfamily B member 1 0.371 0.828 1.3E-05
CUI: C1527249
Disease: Colorectal Cancer
Colorectal Cancer
disease 0.600 1.000 29 5 1996 2018
Entrez Id: 1630
Gene Symbol: DCC
DCC
DCC netrin 1 receptor 0.504 0.655 0.99
CUI: C1527249
Disease: Colorectal Cancer
Colorectal Cancer
disease 0.600 0.923 26 1 1990 2015
Entrez Id: 4893
Gene Symbol: NRAS
NRAS
NRAS proto-oncogene, GTPase 0.420 0.690 0.53
CUI: C1527249
Disease: Colorectal Cancer
Colorectal Cancer
disease 0.600 0.955 22 1 1993 2018
Entrez Id: 3486
Gene Symbol: IGFBP3
IGFBP3
insulin like growth factor binding protein 3 0.464 0.759 0.91
CUI: C1527249
Disease: Colorectal Cancer
Colorectal Cancer
disease 0.600 0.941 17 3 2003 2016
Entrez Id: 5424
Gene Symbol: POLD1
POLD1
DNA polymerase delta 1, catalytic subunit 0.546 0.655 2.2E-06
CUI: C1527249
Disease: Colorectal Cancer
Colorectal Cancer
disease 0.600 strong 1.000 12 2 1995 2018
Entrez Id: 5426
Gene Symbol: POLE
POLE
DNA polymerase epsilon, catalytic subunit 0.616 0.345 1.8E-25
CUI: C1527249
Disease: Colorectal Cancer
Colorectal Cancer
disease 0.600 strong 1.000 12 1 2013 2018
Entrez Id: 3791
Gene Symbol: KDR
KDR
kinase insert domain receptor 0.423 0.724 1.00
CUI: C1527249
Disease: Colorectal Cancer
Colorectal Cancer
disease 0.580 1.000 8 0 2008 2017
Entrez Id: 5979
Gene Symbol: RET
RET
ret proto-oncogene 0.418 0.724 1.00
CUI: C1527249
Disease: Colorectal Cancer
Colorectal Cancer
disease 0.580 1.000 8 0 2008 2016
Entrez Id: 6794
Gene Symbol: STK11
STK11
serine/threonine kinase 11 0.467 0.655 0.99
CUI: C1527249
Disease: Colorectal Cancer
Colorectal Cancer
disease 0.550 strong 1.000 5 0 1998 2015
Entrez Id: 2261
Gene Symbol: FGFR3
FGFR3
fibroblast growth factor receptor 3 0.417 0.759 1.8E-05
CUI: C1527249
Disease: Colorectal Cancer
Colorectal Cancer
disease 0.540 1.000 4 0 2000 2016
Entrez Id: 2070
Gene Symbol: EYA4
EYA4
EYA transcriptional coactivator and phosphatase 4 0.645 0.414 6.3E-02
CUI: C1527249
Disease: Colorectal Cancer
Colorectal Cancer
disease 0.530 1.000 3 0 2006 2016
Entrez Id: 19
Gene Symbol: ABCA1
ABCA1
ATP binding cassette subfamily A member 1 0.484 0.793 3.5E-12
CUI: C1527249
Disease: Colorectal Cancer
Colorectal Cancer
disease 0.520 1.000 2 0 2003 2013
Entrez Id: 701
Gene Symbol: BUB1B
BUB1B
BUB1 mitotic checkpoint serine/threonine kinase B 0.532 0.724 5.4E-10
CUI: C1527249
Disease: Colorectal Cancer
Colorectal Cancer
disease 0.520 1.000 2 0 1999 2008
Entrez Id: 2033
Gene Symbol: EP300
EP300
E1A binding protein p300 0.489 0.828 1.00
CUI: C1527249
Disease: Colorectal Cancer
Colorectal Cancer
disease 0.520 1.000 2 0 2000 2013