Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 7124
Gene Symbol: TNF
TNF
tumor necrosis factor 0.231 0.962 0.80
Chemical and Drug Induced Liver Injury
disease 0.500 None 1.000 6 0 1995 2019
Entrez Id: 1571
Gene Symbol: CYP2E1
CYP2E1
cytochrome P450 family 2 subfamily E member 1 0.459 0.885 8.1E-09
Chemical and Drug Induced Liver Injury
disease 0.500 None 1.000 4 0 2003 2018
Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1
heme oxygenase 1 0.381 0.923 9.7E-03
Chemical and Drug Induced Liver Injury
disease 0.500 None 1.000 2 0 2008 2013
Entrez Id: 847
Gene Symbol: CAT
CAT
catalase 0.359 0.962 1.6E-10
Chemical and Drug Induced Liver Injury
disease 0.500 None 1.000 2 0 2011 2015
Entrez Id: 2944
Gene Symbol: GSTM1
GSTM1
glutathione S-transferase mu 1 0.380 0.923 2.1E-03
Chemical and Drug Induced Liver Injury
disease 0.500 None 1.000 2 0 2007 2011
Entrez Id: 2936
Gene Symbol: GSR
GSR
glutathione-disulfide reductase 0.494 0.846 1.3E-06
Chemical and Drug Induced Liver Injury
disease 0.500 None 1.000 2 0 2013 2017
Entrez Id: 2875
Gene Symbol: GPT
GPT
glutamic--pyruvic transaminase 0.403 0.923 3.6E-19
Chemical and Drug Induced Liver Injury
disease 0.500 None 1.000 2 0 1977 2016
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
interleukin 1 beta 0.276 0.962 0.13
Chemical and Drug Induced Liver Injury
disease 0.500 None 1.000 2 0 2009 2019
Entrez Id: 5428
Gene Symbol: POLG
POLG
DNA polymerase gamma, catalytic subunit 0.457 0.846 2.1E-09
Chemical and Drug Induced Liver Injury
disease 0.500 None 1.000 2 0 2008 2014
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1
ATP binding cassette subfamily B member 1 0.344 0.885 1.3E-05
Chemical and Drug Induced Liver Injury
disease 0.500 None 1.000 1 0 2011 2015
Entrez Id: 2729
Gene Symbol: GCLC
GCLC
glutamate-cysteine ligase catalytic subunit 0.509 0.885 0.43
Chemical and Drug Induced Liver Injury
disease 0.500 None 1.000 1 0 2007 2009
Entrez Id: 60
Gene Symbol: ACTB
ACTB
actin beta 0.325 0.923 0.99
Chemical and Drug Induced Liver Injury
disease 0.500 None 1.000 1 0 2012 2015
Entrez Id: 9971
Gene Symbol: NR1H4
NR1H4
nuclear receptor subfamily 1 group H member 4 0.513 0.808 9.4E-04
Chemical and Drug Induced Liver Injury
disease 0.500 None 1.000 1 0 2003 2018
Entrez Id: 350
Gene Symbol: APOH
APOH
apolipoprotein H 0.563 0.769 1.6E-15
Chemical and Drug Induced Liver Injury
disease 0.500 None 1.000 1 0 2005 2013
Entrez Id: 761
Gene Symbol: CA3
CA3
carbonic anhydrase 3 0.682 0.500 1.7E-03
Chemical and Drug Induced Liver Injury
disease 0.500 None 1.000 1 0 2014 2015
Entrez Id: 7450
Gene Symbol: VWF
VWF
von Willebrand factor 0.408 0.885 3.2E-25
Chemical and Drug Induced Liver Injury
disease 0.500 None 1.000 1 0 1995 2017
Entrez Id: 3105
Gene Symbol: HLA-A
HLA-A
major histocompatibility complex, class I, A 0.370 0.846 1.3E-03
Chemical and Drug Induced Liver Injury
disease 0.400 None 1.000 2 1 2011 2017
Entrez Id: 3119
Gene Symbol: HLA-DQB1
HLA-DQB1
major histocompatibility complex, class II, DQ beta 1 0.407 0.885 8.9E-03
Chemical and Drug Induced Liver Injury
disease 0.400 None 1.000 1 1 2011 2011
Entrez Id: 406906
Gene Symbol: MIR122
MIR122
microRNA 122 0.468 0.808
Chemical and Drug Induced Liver Injury
disease 0.300 None 1.000 7 0 2011 2017
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2
nuclear factor, erythroid 2 like 2 0.357 0.885 3.6E-03
Chemical and Drug Induced Liver Injury
disease 0.300 None 1.000 5 0 2012 2019
Entrez Id: 406967
Gene Symbol: MIR192
MIR192
microRNA 192 0.503 0.846
Chemical and Drug Induced Liver Injury
disease 0.300 None 1.000 4 0 2011 2017
Entrez Id: 10
Gene Symbol: NAT2
NAT2
N-acetyltransferase 2 0.451 0.885 3.3E-06
Chemical and Drug Induced Liver Injury
disease 0.300 None 1.000 4 0 2002 2015
Entrez Id: 50616
Gene Symbol: IL22
IL22
interleukin 22 0.393 0.885 1.9E-04
Chemical and Drug Induced Liver Injury
disease 0.300 None 1.000 3 0 2004 2013
Entrez Id: 1559
Gene Symbol: CYP2C9
CYP2C9
cytochrome P450 family 2 subfamily C member 9 0.506 0.885 1.3E-10
Chemical and Drug Induced Liver Injury
disease 0.300 None 1.000 3 0 2004 2018
Entrez Id: 3565
Gene Symbol: IL4
IL4
interleukin 4 0.332 0.962 4.7E-03
Chemical and Drug Induced Liver Injury
disease 0.300 None 1.000 3 0 2011 2012