Source: CLINVAR

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 5979
Gene Symbol: RET
RET
ret proto-oncogene 0.392 0.885 1.00
Multiple Endocrine Neoplasia Type 2b
disease 1.000 None 1.000 31 15 1992 2019
Entrez Id: 5979
Gene Symbol: RET
RET
ret proto-oncogene 0.392 0.885 1.00
CUI: C0031511
Disease: Pheochromocytoma
Pheochromocytoma
disease 1.000 None 0.960 0 8 1990 2019
Entrez Id: 5979
Gene Symbol: RET
RET
ret proto-oncogene 0.392 0.885 1.00
Multiple Endocrine Neoplasia Type 2a
disease 0.800 None 0.989 93 31 1990 2019
Entrez Id: 5979
Gene Symbol: RET
RET
ret proto-oncogene 0.392 0.885 1.00
CUI: C0549473
Disease: Thyroid carcinoma
Thyroid carcinoma
disease 0.800 None 0.994 3 1 1991 2019
Entrez Id: 5979
Gene Symbol: RET
RET
ret proto-oncogene 0.392 0.885 1.00
Familial medullary thyroid carcinoma
disease 0.800 None 0.960 1 15 1993 2019
Entrez Id: 5979
Gene Symbol: RET
RET
ret proto-oncogene 0.392 0.885 1.00
CUI: C1275808
Disease: Congenital central hypoventilation
Congenital central hypoventilation
disease 0.750 None 1.000 0 3 1996 2017
Entrez Id: 5979
Gene Symbol: RET
RET
ret proto-oncogene 0.392 0.885 1.00
CUI: C0019569
Disease: Hirschsprung Disease
Hirschsprung Disease
disease 0.700 None 0.980 29 15 1993 2019
Entrez Id: 5979
Gene Symbol: RET
RET
ret proto-oncogene 0.392 0.885 1.00
CUI: C0238462
Disease: Medullary carcinoma of thyroid
Medullary carcinoma of thyroid
disease 0.700 strong 0.953 16 18 1992 2020
Entrez Id: 5979
Gene Symbol: RET
RET
ret proto-oncogene 0.392 0.885 1.00
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm
disease 0.700 None 0.994 10 2 1992 2019
Entrez Id: 5979
Gene Symbol: RET
RET
ret proto-oncogene 0.392 0.885 1.00
CUI: C0027662
Disease: Multiple Endocrine Neoplasia
Multiple Endocrine Neoplasia
disease 0.700 strong 0.976 0 1 1994 2018
Entrez Id: 5979
Gene Symbol: RET
RET
ret proto-oncogene 0.392 0.885 1.00
HIRSCHSPRUNG DISEASE, SUSCEPTIBILITY TO, 1
disease 0.600 None 1.000 0 19 1994 2011
Entrez Id: 5979
Gene Symbol: RET
RET
ret proto-oncogene 0.392 0.885 1.00
CUI: C1619700
Disease: RENAL ADYSPLASIA
RENAL ADYSPLASIA
disease 0.440 None 1.000 0 1 2001 2014
Entrez Id: 5979
Gene Symbol: RET
RET
ret proto-oncogene 0.392 0.885 1.00
CUI: C4048306
Disease: Multiple endocrine neoplasia Type 2
Multiple endocrine neoplasia Type 2
disease 0.200 None 0.993 251 35 1991 2019
Entrez Id: 5979
Gene Symbol: RET
RET
ret proto-oncogene 0.392 0.885 1.00
CUI: C0027672
Disease: Neoplastic Syndromes, Hereditary
Neoplastic Syndromes, Hereditary
group 0.200 None 1.000 92 13 1992 2018
Entrez Id: 5979
Gene Symbol: RET
RET
ret proto-oncogene 0.392 0.885 1.00
CUI: C0025267
Disease: Multiple Endocrine Neoplasia Type 1
Multiple Endocrine Neoplasia Type 1
disease 0.200 None 1.000 6 14 1995 2019
Entrez Id: 5979
Gene Symbol: RET
RET
ret proto-oncogene 0.392 0.885 1.00
CUI: C0027651
Disease: Neoplasms
Neoplasms
group 0.200 None 0.940 1 2 1989 2020
Entrez Id: 5979
Gene Symbol: RET
RET
ret proto-oncogene 0.392 0.885 1.00
THYROID CARCINOMA, SPORADIC MEDULLARY
disease 0.200 None 0.984 0 1 1994 2018
Entrez Id: 5979
Gene Symbol: RET
RET
ret proto-oncogene 0.392 0.885 1.00
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast
disease 0.200 None 1.000 0 2 2007 2019
Entrez Id: 5979
Gene Symbol: RET
RET
ret proto-oncogene 0.392 0.885 1.00
CUI: C0009806
Disease: Constipation
Constipation
phenotype 0.130 None 1.000 0 1 2000 2019
Entrez Id: 5979
Gene Symbol: RET
RET
ret proto-oncogene 0.392 0.885 1.00
CUI: C0162316
Disease: Iron deficiency anemia
Iron deficiency anemia
disease 0.120 None 1.000 0 1 2017 2019
Entrez Id: 5979
Gene Symbol: RET
RET
ret proto-oncogene 0.392 0.885 1.00
CUI: C0020676
Disease: Hypothyroidism
Hypothyroidism
disease 0.110 None 1.000 0 1 2004 2004
Entrez Id: 5979
Gene Symbol: RET
RET
ret proto-oncogene 0.392 0.885 1.00
CUI: C0026827
Disease: Muscle hypotonia
Muscle hypotonia
phenotype 0.100 None 1.000 12 1 1994 2012
Entrez Id: 5979
Gene Symbol: RET
RET
ret proto-oncogene 0.392 0.885 1.00
Multiple Endocrine Neoplasia, Type IV
disease 0.100 None 1.000 6 14 1995 2005
Entrez Id: 5979
Gene Symbol: RET
RET
ret proto-oncogene 0.392 0.885 1.00
CUI: C0349588
Disease: Short stature
Short stature
phenotype 0.100 None 0 1
Entrez Id: 5979
Gene Symbol: RET
RET
ret proto-oncogene 0.392 0.885 1.00
MULTIPLE ENDOCRINE NEOPLASIA, TYPE IIA, WITH HIRSCHSPRUNG DISEASE
disease 0.100 None 0 2