Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6582
Gene Symbol: SLC22A2
SLC22A2
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.200 Biomarker RGD Protein and mRNA expression levels of Oat1, Oat 3, Oct1, and Oct2 were significantly decreased in adenine-induced CRF rats. 23280877

2013

Entrez Id: 6582
Gene Symbol: SLC22A2
SLC22A2
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.200 Biomarker RGD Also, serum from CRF rats did not affect Oat1, Oat3, Oct1, and Oct2 function. 23280877

2013

Entrez Id: 6582
Gene Symbol: SLC22A2
SLC22A2
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.200 Biomarker RGD In conclusion, our results indicate that adenine-induced CRF affects renal tubular handling of drugs, especially substrates of Oat1, Oat3, Oct1, and Oct2. 23280877

2013

Entrez Id: 6582
Gene Symbol: SLC22A2
SLC22A2
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.200 Biomarker RGD Renal uptake of substrates for organic anion transporters Oat1 and Oat3 and organic cation transporters Oct1 and Oct2 is altered in rats with adenine-induced chronic renal failure. 23280877

2013

Entrez Id: 6582
Gene Symbol: SLC22A2
SLC22A2
CUI: C0022661
Disease: Kidney Failure, Chronic
Kidney Failure, Chronic
0.200 Biomarker RGD Down-regulation of rat organic cation transporter rOCT2 by 5/6 nephrectomy. 12110012

2002