Source: ANIMAL_MODELS

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1636
Gene Symbol: ACE
ACE
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.600 Therapeutic RGD MI also significantly increased ACE and angiotensin type 1 receptor levels but decreased ACE2 activity by 40% (control, 246.2±25.1; DIZE alone, 254.2±20.6; MI, 148.9±29.2; RFU/min), which was reversed by DIZE treatment. 23959549

2013

Entrez Id: 1636
Gene Symbol: ACE
ACE
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.600 Biomarker RGD Effects of captopril and angiotensin II receptor blockers (AT1, AT2) on myocardial ischemia-reperfusion induced infarct size. 21975128

2011

Entrez Id: 1636
Gene Symbol: ACE
ACE
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.600 Therapeutic RGD Both ACE (P = 0.022) and ACE2 (P = 0.015) mRNA increased in the border/infarct area compared with the viable area at day 3 after MI. 15671045

2005

Entrez Id: 1636
Gene Symbol: ACE
ACE
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.600 Therapeutic RGD By day 28, increases in ACE (P = 0.005) and ACE2 (P = 0.006) mRNA were also seen in the viable myocardium of MI rats compared with myocardium of control rats. 15671045

2005

Entrez Id: 1636
Gene Symbol: ACE
ACE
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.600 Therapeutic RGD Rats were killed at days 1, 3, and 28 after MI, or treated for 4 weeks with the ACE inhibitor ramipril (1 mg/kg). 15671045

2005