Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2271
Gene Symbol: FH
FH
CUI: C0344456
Disease: Malignant Adrenal Medulla Neoplasm
Malignant Adrenal Medulla Neoplasm
0.300 Biomarker CLINGEN Inactivation of SDH and FH cause loss of 5hmC and increased H3K9me3 in paraganglioma/pheochromocytoma and smooth muscle tumors. 26472283

2016

Entrez Id: 2271
Gene Symbol: FH
FH
CUI: C0344456
Disease: Malignant Adrenal Medulla Neoplasm
Malignant Adrenal Medulla Neoplasm
0.300 Biomarker CLINGEN Germline FH mutations presenting with pheochromocytoma. 25004247

2015

Entrez Id: 2271
Gene Symbol: FH
FH
CUI: C0344456
Disease: Malignant Adrenal Medulla Neoplasm
Malignant Adrenal Medulla Neoplasm
0.300 Biomarker CLINGEN Germline mutations in FH confer predisposition to malignant pheochromocytomas and paragangliomas. 24334767

2014

Entrez Id: 2271
Gene Symbol: FH
FH
CUI: C0344456
Disease: Malignant Adrenal Medulla Neoplasm
Malignant Adrenal Medulla Neoplasm
0.300 Biomarker CLINGEN SDH mutations establish a hypermethylator phenotype in paraganglioma. 23707781

2013

Entrez Id: 2271
Gene Symbol: FH
FH
CUI: C0344456
Disease: Malignant Adrenal Medulla Neoplasm
Malignant Adrenal Medulla Neoplasm
0.300 Biomarker CLINGEN Increased HIF1 alpha in SDH and FH deficient tumors does not cause microsatellite instability. 17520677

2007

Entrez Id: 2271
Gene Symbol: FH
FH
CUI: C0344456
Disease: Malignant Adrenal Medulla Neoplasm
Malignant Adrenal Medulla Neoplasm
0.300 Biomarker CLINGEN Accumulation of Krebs cycle intermediates and over-expression of HIF1alpha in tumours which result from germline FH and SDH mutations. 15987702

2005