Source: CLINGEN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 60561
Gene Symbol: RINT1
RINT1
CUI: C0346153
Disease: Breast Cancer, Familial
Breast Cancer, Familial 		0.300 Biomarker CLINGEN The coding regions and exon-intron boundaries of RINT1 were sequenced in 2024 familial breast cancer cases previously tested negative for BRCA1, BRCA2, and PALB2 mutations and 1886 population-matched cancer-free controls using HaloPlex Targeted Enrichment Assays. 27544226

2016
Entrez Id: 60561
Gene Symbol: RINT1
RINT1
CUI: C0346153
Disease: Breast Cancer, Familial
Breast Cancer, Familial 		0.300 Biomarker CLINGEN Rint1 inactivation triggers genomic instability, ER stress and autophagy inhibition in the brain. 26383973

2016
Entrez Id: 60561
Gene Symbol: RINT1
RINT1
CUI: C0346153
Disease: Breast Cancer, Familial
Breast Cancer, Familial 		0.300 Biomarker CLINGEN Rare mutations in RINT1 predispose carriers to breast and Lynch syndrome-spectrum cancers. 25050558

2014
Entrez Id: 60561
Gene Symbol: RINT1
RINT1
CUI: C0346153
Disease: Breast Cancer, Familial
Breast Cancer, Familial 		0.300 Biomarker CLINGEN RINT-1 serves as a tumor suppressor and maintains Golgi dynamics and centrosome integrity for cell survival. 17470549

2007
Entrez Id: 60561
Gene Symbol: RINT1
RINT1
CUI: C0346153
Disease: Breast Cancer, Familial
Breast Cancer, Familial 		0.300 Biomarker CLINGEN RINT-1, a novel Rad50-interacting protein, participates in radiation-induced G(2)/M checkpoint control. 11096100

2001