Source: CTD_human

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6532
Gene Symbol: SLC6A4
SLC6A4
CUI: C0004352
Disease: Autistic Disorder
Autistic Disorder 		0.400 Biomarker CTD_human This is the first South African study of autistic individuals of different ethnic backgrounds that shows significant differences in allele and genotype frequencies of 5-HTTLPR. 20649385

2010
Entrez Id: 6532
Gene Symbol: SLC6A4
SLC6A4
CUI: C0004352
Disease: Autistic Disorder
Autistic Disorder 		0.400 Biomarker CTD_human We report a significant main effect of the HTR5A gene in autism (P = 0.0088), and a significant three-locus model comprising a synergistic interaction between the ITGB3 and SLC6A4 genes with an additive effect of HTR5A (P < 0.0010). 17203304

2007
Entrez Id: 6532
Gene Symbol: SLC6A4
SLC6A4
CUI: C0004352
Disease: Autistic Disorder
Autistic Disorder 		0.400 Biomarker CTD_human Family-based association study of 5-HTTLPR and the 5-HT2A receptor gene polymorphisms with autism spectrum disorder in Korean trios. 17280648

2007
Entrez Id: 6532
Gene Symbol: SLC6A4
SLC6A4
CUI: C0004352
Disease: Autistic Disorder
Autistic Disorder 		0.400 Biomarker CTD_human We also show preliminary evidence that genotypes at the ITGB3 and SLC6A4 loci may interact to affect autism susceptibility (P=0.033). 16721604

2006
Entrez Id: 6532
Gene Symbol: SLC6A4
SLC6A4
CUI: C0004352
Disease: Autistic Disorder
Autistic Disorder 		0.400 Biomarker CTD_human Evidence of linkage between the serotonin transporter and autistic disorder. 9152989

1997