Source: CTD_human

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon 		0.500 Biomarker CTD_human In this study, we demonstrate that K-Ras, a frequently altered oncogene in human cancers including pancreatic cancer (about 80%), colon cancer (45%) and lung cancer (45%), suppresses p53. 19424582

2009
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon 		0.500 Biomarker CTD_human This K-Ras tumor phenotype was associated with attenuated signaling through the MAPK pathway, and human colon cancer cells expressing mutant K-Ras were hypersensitive to inhibition of Raf, but not Mek. 18372904

2008
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon 		0.500 Biomarker CTD_human Comet fluorescence in situ hybridization analysis for oxidative stress-induced DNA damage in colon cancer relevant genes. 17192441

2007
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon 		0.500 Biomarker CTD_human Ursodeoxycholic acid inhibits Ras mutations, wild-type Ras activation, and cyclooxygenase-2 expression in colon cancer. 12839936

2003
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon 		0.500 Biomarker CTD_human Expression profiling of CC531 colon carcinoma cells reveals similar regulation of beta-catenin target genes by both butyrate and aspirin. 12800193

2003
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon 		0.500 Biomarker CTD_human ras p21 Isoprenylation inhibition induces flat colon tumors in Wistar rats. 10813127

2000