Source: CTD_human

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.700 Biomarker CTD_human These data highlight the potential utility of eNOS gene therapy in the treatment of hypertension and insulin resistance. 19008412

2009
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.700 Therapeutic CTD_human These data highlight the potential utility of eNOS gene therapy in the treatment of hypertension and insulin resistance. 19008412

2009
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.700 Biomarker CTD_human Genetic and pharmacogenetic associations between NOS3 polymorphisms, blood pressure, and cardiovascular events in hypertension. 19407804

2009
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.700 Therapeutic CTD_human Genetic and pharmacogenetic associations between NOS3 polymorphisms, blood pressure, and cardiovascular events in hypertension. 19407804

2009
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.700 Therapeutic CTD_human Quercetin downregulates NADPH oxidase, increases eNOS activity and prevents endothelial dysfunction in spontaneously hypertensive rats. 16331104

2006
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.700 Biomarker CTD_human Quercetin downregulates NADPH oxidase, increases eNOS activity and prevents endothelial dysfunction in spontaneously hypertensive rats. 16331104

2006
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.700 Biomarker CTD_human Clustering of cardiovascular risk factors mimicking the human metabolic syndrome X in eNOS null mice. 12947532

2003
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.700 Therapeutic CTD_human Clustering of cardiovascular risk factors mimicking the human metabolic syndrome X in eNOS null mice. 12947532

2003
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.700 Biomarker CTD_human Insulin resistance in eNOS(-/-) mice was related specifically to impaired NO synthesis, because in equally hypertensive 1-kidney/1-clip mice (a model of renovascular hypertension), insulin-stimulated glucose uptake was normal. 11457755

2001
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.700 Therapeutic CTD_human Insulin resistance in eNOS(-/-) mice was related specifically to impaired NO synthesis, because in equally hypertensive 1-kidney/1-clip mice (a model of renovascular hypertension), insulin-stimulated glucose uptake was normal. 11457755

2001