Source: CTD_human

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
CUI: C0025202
Disease: melanoma
melanoma 		0.800 Biomarker CTD_human Genes deregulated at the DNA and mRNA level included well-known cancer genes partly already linked to melanoma (RAS genes, PTEN, AURKA, MAPK inhibitors Sprouty/Spred), but also novel candidates like SIPA1 (a Rap1GAP). 22535842

2012
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
CUI: C0025202
Disease: melanoma
melanoma 		0.800 Biomarker CTD_human Braf(V600E) cooperates with Pten loss to induce metastatic melanoma. 19282848

2009
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
CUI: C0025202
Disease: melanoma
melanoma 		0.800 Biomarker CTD_human These data support the notion that PTEN alterations occur in some metastatic melanomas, and that mutation of this gene plays a role in the progression of some forms of melanoma. 10978354

2000