Source: CTD_human

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 627
Gene Symbol: BDNF
BDNF
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.400 Biomarker CTD_human These findings suggest that BDNF plays an important role in the susceptibility to schizophrenia and that the (GT)n repeat polymorphism of the BDNF gene may be an independent contributor to the chlorpromazine treatment-sensitive form of schizophrenia. 18408624

2008

Entrez Id: 627
Gene Symbol: BDNF
BDNF
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.400 Biomarker CTD_human Chronic administration of drugs used to treat SZ and BD, such as lithium, valproate, quetiapine, clozapine, and olanzapine, increases BDNF expression in rat brain. 17442489

2007

Entrez Id: 627
Gene Symbol: BDNF
BDNF
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.400 Biomarker CTD_human Molecular abnormalities of the hippocampus in severe psychiatric illness: postmortem findings from the Stanley Neuropathology Consortium. 14708030

2004

Entrez Id: 627
Gene Symbol: BDNF
BDNF
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
0.400 Biomarker CTD_human Our finding suggests that this BDNF-gene Val66Met polymorphism may be related to schizophrenia pathogenesis in patients responsive to clozapine treatment. 12951204

2003