Source: CTD_mouse

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0018923
Disease: Hemangiosarcoma
Hemangiosarcoma 		0.600 Biomarker CTD_mouse Final report on carcinogens background document for riddelliine. 20737008

2008
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0018923
Disease: Hemangiosarcoma
Hemangiosarcoma 		0.600 Biomarker CTD_mouse Our data indicated that p53 and beta-catenin mutations in the o-nitrotoluene-induced hemangiosarcomas and K-ras mutations and p53 protein expression in riddelliine-induced hemangiosarcomas most likely occurred as a result of the genotoxic effects of these chemicals. 13678655

2003
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0018923
Disease: Hemangiosarcoma
Hemangiosarcoma 		0.600 Biomarker CTD_mouse Our data indicate that K-ras, H-ras, and p53 mutations in these hemangiosarcomas most likely occurred as a result of the genotoxic effects of BD and that these mutations may play a role in the pathogenesis of BD-induced cardiac hemangiosarcomas in the B6C3F1 mouse. 10930038

2001