Source: GWASCAT

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 64127
Gene Symbol: NOD2
NOD2
nucleotide binding oligomerization domain containing 2 0.423 0.923 2.0E-30
CUI: C0010346
Disease: Crohn Disease
Crohn Disease
disease 1.000 moderate 0.937 13 8 1998 2019
Entrez Id: 3172
Gene Symbol: HNF4A
HNF4A
hepatocyte nuclear factor 4 alpha 0.461 0.808 0.15
Diabetes Mellitus, Non-Insulin-Dependent
disease 1.000 None 0.942 8 5 1992 2019
Entrez Id: 5078
Gene Symbol: PAX4
PAX4
paired box 4 0.644 0.423 4.2E-04
Diabetes Mellitus, Non-Insulin-Dependent
disease 1.000 limited 0.857 2 1 1999 2019
Entrez Id: 5621
Gene Symbol: PRNP
PRNP
prion protein 0.445 0.923 6.3E-04
CUI: C0022336
Disease: Creutzfeldt-Jakob disease
Creutzfeldt-Jakob disease
disease 1.000 strong 0.980 2 2 1988 2020
Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A
sodium voltage-gated channel alpha subunit 5 0.513 0.654 0.91
CUI: C1142166
Disease: Brugada Syndrome (disorder)
Brugada Syndrome (disorder)
disease 1.000 definitive 0.984 1 1 1995 2020
Entrez Id: 3767
Gene Symbol: KCNJ11
KCNJ11
potassium inwardly rectifying channel subfamily J member 11 0.529 0.615 1.1E-02
Diabetes Mellitus, Non-Insulin-Dependent
disease 0.900 strong 0.943 10 3 1996 2019
Entrez Id: 26191
Gene Symbol: PTPN22
PTPN22
protein tyrosine phosphatase non-receptor type 22 0.438 0.846 3.5E-21
Diabetes Mellitus, Insulin-Dependent
disease 0.900 None 0.945 6 1 2004 2020
Entrez Id: 6927
Gene Symbol: HNF1A
HNF1A
HNF1 homeobox A 0.478 0.846 0.96
Diabetes Mellitus, Non-Insulin-Dependent
disease 0.900 strong 0.954 3 4 1995 2019
Entrez Id: 7157
Gene Symbol: TP53
TP53
tumor protein p53 0.236 0.962 0.53
CUI: C0017638
Disease: Glioma
Glioma
disease 0.900 None 0.946 3 2 1991 2020
Entrez Id: 389421
Gene Symbol: LIN28B
LIN28B
lin-28 homolog B 0.556 0.654 0.56
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma
disease 0.900 None 1.000 2 1 2012 2020
Entrez Id: 1636
Gene Symbol: ACE
ACE
angiotensin I converting enzyme 0.328 0.923 1.0E-37
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
disease 0.900 strong 0.915 1 1 1998 2020
Entrez Id: 2645
Gene Symbol: GCK
GCK
glucokinase 0.523 0.808 0.63
Diabetes Mellitus, Non-Insulin-Dependent
disease 0.900 strong 0.953 1 1 1992 2020
Entrez Id: 324
Gene Symbol: APC
APC
APC regulator of WNT signaling pathway 0.373 0.962 1.00
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms
group 0.900 None 0.982 1 1 1990 2019
Entrez Id: 3664
Gene Symbol: IRF6
IRF6
interferon regulatory factor 6 0.486 0.769 1.00
CUI: C0008924
Disease: Cleft upper lip
Cleft upper lip
disease 0.900 None 0.923 1 1 2003 2019
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
BRCA2 DNA repair associated 0.379 0.846 2.4E-25
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm
disease 0.900 None 0.947 1 2 1994 2020
Entrez Id: 9863
Gene Symbol: MAGI2
MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2 0.579 0.654 1.00
CUI: C0036341
Disease: Schizophrenia
Schizophrenia
disease 0.850 None 1.000 2 2 2008 2018
Entrez Id: 6928
Gene Symbol: HNF1B
HNF1B
HNF1 homeobox B 0.473 0.808 1.00
Diabetes Mellitus, Non-Insulin-Dependent
disease 0.800 None 0.978 8 5 1998 2019
Entrez Id: 203228
Gene Symbol: C9orf72
C9orf72
C9orf72-SMCR8 complex subunit 0.496 0.769 1.1E-06
CUI: C0002736
Disease: Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis
disease 0.800 limited 0.985 7 4 2009 2020
Entrez Id: 26191
Gene Symbol: PTPN22
PTPN22
protein tyrosine phosphatase non-receptor type 22 0.438 0.846 3.5E-21
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic
disease 0.800 None 0.952 6 1 2004 2019
Entrez Id: 3119
Gene Symbol: HLA-DQB1
HLA-DQB1
major histocompatibility complex, class II, DQ beta 1 0.407 0.885 8.9E-03
CUI: C0027404
Disease: Narcolepsy
Narcolepsy
disease 0.800 limited 0.956 1 1 1996 2019
Entrez Id: 324
Gene Symbol: APC
APC
APC regulator of WNT signaling pathway 0.373 0.962 1.00
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
disease 0.800 strong 0.972 1 1 1990 2020
Entrez Id: 6336
Gene Symbol: SCN10A
SCN10A
sodium voltage-gated channel alpha subunit 10 0.566 0.692 9.9E-38
CUI: C1142166
Disease: Brugada Syndrome (disorder)
Brugada Syndrome (disorder)
disease 0.800 disputed 0.929 1 1 1998 2019
Entrez Id: 6622
Gene Symbol: SNCA
SNCA
synuclein alpha 0.427 0.885 0.88
CUI: C0752347
Disease: Lewy Body Disease
Lewy Body Disease
disease 0.800 None 0.973 1 1 1998 2020
Entrez Id: 8626
Gene Symbol: TP63
TP63
tumor protein p63 0.362 0.769 1.00
CUI: C0008924
Disease: Cleft upper lip
Cleft upper lip
disease 0.720 strong 1.000 1 1 2006 2017
Entrez Id: 6934
Gene Symbol: TCF7L2
TCF7L2
transcription factor 7 like 2 0.485 0.846 1.00
Diabetes Mellitus, Non-Insulin-Dependent
disease 0.700 None 0.965 37 7 2006 2020