×
Entrez Id: 673
Gene Symbol: BRAF
BRAF
Non-Small Cell Lung Carcinoma
0.500
GeneticVariation
CLINVAR
Prospective enterprise-level molecular genotyping of a cohort of cancer patients.
25157968 2014
×
Entrez Id: 673
Gene Symbol: BRAF
BRAF
Non-Small Cell Lung Carcinoma
0.500
CausalMutation
CLINVAR
A structural systems biology approach for quantifying the systemic consequences of missense mutations in proteins.
23093928 2012
×
Entrez Id: 673
Gene Symbol: BRAF
BRAF
Non-Small Cell Lung Carcinoma
0.500
CausalMutation
CLINVAR
Distinguishing clinicopathologic features of patients with V600E and V600K BRAF-mutant metastatic melanoma.
22535154 2012
×
Entrez Id: 673
Gene Symbol: BRAF
BRAF
Non-Small Cell Lung Carcinoma
0.500
CausalMutation
CLINVAR
The intermediate-activity (L597V)BRAF mutant acts as an epistatic modifier of oncogenic RAS by enhancing signaling through the RAF/MEK/ERK pathway.
22892241 2012
×
Entrez Id: 673
Gene Symbol: BRAF
BRAF
Non-Small Cell Lung Carcinoma
0.500
CausalMutation
CLINVAR
Functional characterization of a BRAF insertion mutant associated with pilocytic astrocytoma.
21190184 2011
×
Entrez Id: 673
Gene Symbol: BRAF
BRAF
Non-Small Cell Lung Carcinoma
0.500
CausalMutation
CLINVAR
Prognostic and clinicopathologic associations of oncogenic BRAF in metastatic melanoma.
21343559 2011
×
Entrez Id: 673
Gene Symbol: BRAF
BRAF
Non-Small Cell Lung Carcinoma
0.500
CausalMutation
CLINVAR
BRAF, p53 and SOX2 in anaplastic thyroid carcinoma: evidence for multistep carcinogenesis.
21716161 2011
×
Entrez Id: 673
Gene Symbol: BRAF
BRAF
Non-Small Cell Lung Carcinoma
0.500
GeneticVariation
CLINVAR
KRAS and BRAF mutations in patients with rectal cancer treated with preoperative chemoradiotherapy.
19913317 2010
×
Entrez Id: 673
Gene Symbol: BRAF
BRAF
Non-Small Cell Lung Carcinoma
0.500
CausalMutation
CLINVAR
Distinct gene mutation profiles among luminal-type and basal-type breast cancer cell lines.
19593635 2010
×
Entrez Id: 673
Gene Symbol: BRAF
BRAF
Non-Small Cell Lung Carcinoma
0.500
CausalMutation
CLINVAR
Germline BRAF mutations in Noonan, LEOPARD, and cardiofaciocutaneous syndromes: molecular diversity and associated phenotypic spectrum.
19206169 2009
×
Entrez Id: 673
Gene Symbol: BRAF
BRAF
Non-Small Cell Lung Carcinoma
0.500
CausalMutation
CLINVAR
Alterations of BRAF and HIPK2 loci predominate in sporadic pilocytic astrocytoma.
19794125 2009
×
Entrez Id: 673
Gene Symbol: BRAF
BRAF
Non-Small Cell Lung Carcinoma
0.500
CausalMutation
CLINVAR
Oncogenic RAF1 rearrangement and a novel BRAF mutation as alternatives to KIAA1549:BRAF fusion in activating the MAPK pathway in pilocytic astrocytoma.
19363522 2009
×
Entrez Id: 673
Gene Symbol: BRAF
BRAF
Non-Small Cell Lung Carcinoma
0.500
GeneticVariation
CLINVAR
MC1R variants increase risk of melanomas harboring BRAF mutations.
18368129 2008
×
Entrez Id: 673
Gene Symbol: BRAF
BRAF
Non-Small Cell Lung Carcinoma
0.500
GeneticVariation
CLINVAR
Gene expression signature associated with BRAF mutations in human primary cutaneous melanomas.
19383316 2008
×
Entrez Id: 673
Gene Symbol: BRAF
BRAF
Non-Small Cell Lung Carcinoma
0.500
GeneticVariation
CLINVAR
B-RAF and N-RAS mutations are preserved during short time in vitro propagation and differentially impact prognosis.
17311103 2007
×
Entrez Id: 673
Gene Symbol: BRAF
BRAF
Non-Small Cell Lung Carcinoma
0.500
CausalMutation
CLINVAR
Phosphatidylinositol-3-OH kinase or RAS pathway mutations in human breast cancer cell lines.
17314276 2007
×
Entrez Id: 673
Gene Symbol: BRAF
BRAF
Non-Small Cell Lung Carcinoma
0.500
GeneticVariation
CLINVAR
Diet and lifestyle factor associations with CpG island methylator phenotype and BRAF mutations in colon cancer.
17096326 2007
×
Entrez Id: 673
Gene Symbol: BRAF
BRAF
Non-Small Cell Lung Carcinoma
0.500
GeneticVariation
CLINVAR
NRAS and BRAF mutations in melanoma tumours in relation to clinical characteristics: a study based on mutation screening by pyrosequencing.
17119447 2006
×
Entrez Id: 673
Gene Symbol: BRAF
BRAF
Non-Small Cell Lung Carcinoma
0.500
GeneticVariation
CLINVAR
Inactivation of the mitogen-activated protein kinase pathway as a potential target-based therapy in ovarian serous tumors with KRAS or BRAF mutations.
15753399 2005
×
Entrez Id: 673
Gene Symbol: BRAF
BRAF
Non-Small Cell Lung Carcinoma
0.500
GeneticVariation
CLINVAR
Constitutive activation of the Ras-Raf signaling pathway in metastatic melanoma is associated with poor prognosis.
15046639 2004
×
Entrez Id: 673
Gene Symbol: BRAF
BRAF
Non-Small Cell Lung Carcinoma
0.500
CausalMutation
CLINVAR
Mutation analysis of the BRAF, ARAF and RAF-1 genes in human colorectal adenocarcinomas.
14688025 2004
×
Entrez Id: 673
Gene Symbol: BRAF
BRAF
Non-Small Cell Lung Carcinoma
0.500
CausalMutation
CLINVAR
Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF.
15035987 2004
×
Entrez Id: 673
Gene Symbol: BRAF
BRAF
Non-Small Cell Lung Carcinoma
0.500
GeneticVariation
CLINVAR
High frequency of mutations of the PIK3CA gene in human cancers.
15016963 2004
×
Entrez Id: 673
Gene Symbol: BRAF
BRAF
Non-Small Cell Lung Carcinoma
0.500
GeneticVariation
CLINVAR
Activating BRAF and N-Ras mutations in sporadic primary melanomas: an inverse association with allelic loss on chromosome 9.
14681681 2003
×
Entrez Id: 673
Gene Symbol: BRAF
BRAF
Non-Small Cell Lung Carcinoma
0.500
GeneticVariation
CLINVAR
Mutations of the BRAF gene in human cancer.
12068308 2002