×
Entrez Id:
3845
Gene Symbol:
KRAS
KRAS
Noonan Syndrome
1.000
CausalMutation
CLINVAR
ClinGen's RASopathy Expert Panel consensus methods for variant interpretation.
29493581
2018
×
Entrez Id:
3845
Gene Symbol:
KRAS
KRAS
Noonan Syndrome
1.000
GeneticVariation
CLINVAR
Structure-energy-based predictions and network modelling of RASopathy and cancer missense mutations.
24803665
2014
×
Entrez Id:
3845
Gene Symbol:
KRAS
KRAS
Noonan Syndrome
1.000
GeneticVariation
CLINVAR
Tegumentary manifestations of Noonan and Noonan-related syndromes.
24037001
2013
×
Entrez Id:
3845
Gene Symbol:
KRAS
KRAS
Noonan Syndrome
1.000
GeneticVariation
CLINVAR
High resolution melting analysis of KRAS, BRAF and PIK3CA in KRAS exon 2 wild-type metastatic colorectal cancer.
23548132
2013
×
Entrez Id:
3845
Gene Symbol:
KRAS
KRAS
Noonan Syndrome
1.000
CausalMutation
CLINVAR
Prenatal diagnostic testing of the Noonan syndrome genes in fetuses with abnormal ultrasound findings.
23321623
2013
×
Entrez Id:
3845
Gene Symbol:
KRAS
KRAS
Noonan Syndrome
1.000
CausalMutation
CLINVAR
KRAS gene mutations in Noonan syndrome familial cases cluster in the vicinity of the switch II region of the G-domain: report of another family with metopic craniosynostosis.
22488932
2012
×
Entrez Id:
3845
Gene Symbol:
KRAS
KRAS
Noonan Syndrome
1.000
GeneticVariation
CLINVAR
Multiple, diffuse schwannomas in a RASopathy phenotype patient with germline KRAS mutation: a causal relationship?
22211815
2012
×
Entrez Id:
3845
Gene Symbol:
KRAS
KRAS
Noonan Syndrome
1.000
GeneticVariation
CLINVAR
The importance of evaluation of DNA amplificability in KRAS mutation testing with dideoxy sequencing using formalin-fixed and paraffin-embedded colorectal cancer tissues.
20926413
2011
×
Entrez Id:
3845
Gene Symbol:
KRAS
KRAS
Noonan Syndrome
1.000
CausalMutation
CLINVAR
Germline KRAS mutations cause aberrant biochemical and physical properties leading to developmental disorders.
20949621
2011
×
Entrez Id:
3845
Gene Symbol:
KRAS
KRAS
Noonan Syndrome
1.000
GeneticVariation
CLINVAR
Germline KRAS mutations cause aberrant biochemical and physical properties leading to developmental disorders.
20949621
2011
×
Entrez Id:
3845
Gene Symbol:
KRAS
KRAS
Noonan Syndrome
1.000
GeneticVariation
CLINVAR
Frequent pathway mutations of splicing machinery in myelodysplasia.
21909114
2011
×
Entrez Id:
3845
Gene Symbol:
KRAS
KRAS
Noonan Syndrome
1.000
CausalMutation
CLINVAR
Molecular genotyping of papillary thyroid carcinoma follicular variant according to its histological subtypes (encapsulated vs infiltrative) reveals distinct BRAF and RAS mutation patterns.
20526288
2010
×
Entrez Id:
3845
Gene Symbol:
KRAS
KRAS
Noonan Syndrome
1.000
CausalMutation
CLINVAR
Prenatal detection of Noonan syndrome by mutation analysis of the PTPN11 and the KRAS genes.
20112233
2010
×
Entrez Id:
3845
Gene Symbol:
KRAS
KRAS
Noonan Syndrome
1.000
CausalMutation
CLINVAR
Here, we report on the occurrence of premature closure of cranial sutures in subjects with NS , and their specific association with mutations in the KRAS gene.
19396835
2009
×
Entrez Id:
3845
Gene Symbol:
KRAS
KRAS
Noonan Syndrome
1.000
CausalMutation
CLINVAR
Noonan syndrome caused by germline KRAS mutation in Taiwan: report of two patients and a review of the literature.
18958496
2009
×
Entrez Id:
3845
Gene Symbol:
KRAS
KRAS
Noonan Syndrome
1.000
GeneticVariation
CLINVAR
Noonan syndrome caused by germline KRAS mutation in Taiwan: report of two patients and a review of the literature.
18958496
2009
×
Entrez Id:
3845
Gene Symbol:
KRAS
KRAS
Noonan Syndrome
1.000
GeneticVariation
CLINVAR
Here, we report on the occurrence of premature closure of cranial sutures in subjects with NS , and their specific association with mutations in the KRAS gene.
19396835
2009
×
Entrez Id:
3845
Gene Symbol:
KRAS
KRAS
Noonan Syndrome
1.000
CausalMutation
CLINVAR
An activating KRAS mutation in imatinib-resistant chronic myeloid leukemia.
18509354
2008
×
Entrez Id:
3845
Gene Symbol:
KRAS
KRAS
Noonan Syndrome
1.000
CausalMutation
CLINVAR
High-resolution melting analysis for rapid detection of KRAS, BRAF, and PIK3CA gene mutations in colorectal cancer.
18628094
2008
×
Entrez Id:
3845
Gene Symbol:
KRAS
KRAS
Noonan Syndrome
1.000
CausalMutation
CLINVAR
Noonan and cardio-facio-cutaneous syndromes: two clinically and genetically overlapping disorders.
18456719
2008
×
Entrez Id:
3845
Gene Symbol:
KRAS
KRAS
Noonan Syndrome
1.000
CausalMutation
CLINVAR
The aim of this study was to assess the correlation between phenotype and genotype by molecular analysis of the PTPN11, SOS1, KRAS , and RAF1 genes in 59 Korean patients with NS .
19020799
2008
×
Entrez Id:
3845
Gene Symbol:
KRAS
KRAS
Noonan Syndrome
1.000
CausalMutation
CLINVAR
Expansion of the genotypic and phenotypic spectrum in patients with KRAS germline mutations.
17056636
2007
×
Entrez Id:
3845
Gene Symbol:
KRAS
KRAS
Noonan Syndrome
1.000
CausalMutation
CLINVAR
Congenital ulcerating hemangioma in a baby with KRAS mutation and cardio-facio-cutaneous syndrome.
17551339
2007
×
Entrez Id:
3845
Gene Symbol:
KRAS
KRAS
Noonan Syndrome
1.000
CausalMutation
CLINVAR
We performed detailed biochemical and functional studies of three mutant K-Ras proteins (P34R, D153V, and F156L) found in individuals with Noonan syndrome and cardiofaciocutaneous syndrome.
17875937
2007
×
Entrez Id:
3845
Gene Symbol:
KRAS
KRAS
Noonan Syndrome
1.000
GeneticVariation
CLINVAR
De novo HRAS and KRAS mutations in two siblings with short stature and neuro-cardio-facio-cutaneous features.
17601930
2007