×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Hereditary Nonpolyposis Colorectal Cancer
0.900
CausalMutation
CLINVAR
Evaluation of MLH1 variants of unclear significance.
29520894
2018
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Hereditary Nonpolyposis Colorectal Cancer
0.900
CausalMutation
CLINVAR
DNA mismatch repair deficiency and hereditary syndromes in Latino patients with colorectal cancer.
28640387
2017
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Hereditary Nonpolyposis Colorectal Cancer
0.900
CausalMutation
CLINVAR
Assessment of the InSiGHT Interpretation Criteria for the Clinical Classification of 24 MLH1 and MSH2 Gene Variants.
27629256
2017
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Hereditary Nonpolyposis Colorectal Cancer
0.900
CausalMutation
CLINVAR
A survey of the clinicopathological and molecular characteristics of patients with suspected Lynch syndrome in Latin America.
28874130
2017
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Hereditary Nonpolyposis Colorectal Cancer
0.900
CausalMutation
CLINVAR
Spectrum of mismatch repair gene mutations and clinical presentation of Hispanic individuals with Lynch syndrome.
28449805
2017
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Hereditary Nonpolyposis Colorectal Cancer
0.900
CausalMutation
CLINVAR
Prevalence and Spectrum of Germline Cancer Susceptibility Gene Mutations Among Patients With Early-Onset Colorectal Cancer.
27978560
2017
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Hereditary Nonpolyposis Colorectal Cancer
0.900
CausalMutation
CLINVAR
Lynch syndrome mutation spectrum in New South Wales, Australia, including 55 novel mutations.
27064304
2016
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Hereditary Nonpolyposis Colorectal Cancer
0.900
CausalMutation
CLINVAR
Exonic Splicing Mutations Are More Prevalent than Currently Estimated and Can Be Predicted by Using In Silico Tools.
26761715
2016
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Hereditary Nonpolyposis Colorectal Cancer
0.900
CausalMutation
CLINVAR
Improving performance of multigene panels for genomic analysis of cancer predisposition.
26845104
2016
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Hereditary Nonpolyposis Colorectal Cancer
0.900
CausalMutation
CLINVAR
Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing.
26681312
2016
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Hereditary Nonpolyposis Colorectal Cancer
0.900
CausalMutation
CLINVAR
Systematic immunohistochemical screening for Lynch syndrome in colorectal cancer: a single centre experience of 486 patients.
27152634
2016
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Hereditary Nonpolyposis Colorectal Cancer
0.900
CausalMutation
CLINVAR
Mismatch repair gene mutation spectrum in the Swedish Lynch syndrome population.
27601186
2016
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Hereditary Nonpolyposis Colorectal Cancer
0.900
CausalMutation
CLINVAR
Germline mutations in PMS2 and MLH1 in individuals with solitary loss of PMS2 expression in colorectal carcinomas from the Colon Cancer Family Registry Cohort.
26895986
2016
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Hereditary Nonpolyposis Colorectal Cancer
0.900
GeneticVariation
CLINVAR
Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing.
26681312
2016
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Hereditary Nonpolyposis Colorectal Cancer
0.900
CausalMutation
CLINVAR
Clinical characterization and mutation spectrum in Caribbean Hispanic families with Lynch syndrome.
25782445
2015
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Hereditary Nonpolyposis Colorectal Cancer
0.900
GeneticVariation
CLINVAR
Next-generation sequencing for genetic testing of familial colorectal cancer syndromes.
26300997
2015
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Hereditary Nonpolyposis Colorectal Cancer
0.900
GeneticVariation
CLINVAR
Identification of a Variety of Mutations in Cancer Predisposition Genes in Patients With Suspected Lynch Syndrome.
25980754
2015
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Hereditary Nonpolyposis Colorectal Cancer
0.900
GeneticVariation
CLINVAR
Multivariate analysis as a method for evaluating the pathogenicity of novel genetic MLH1 variants in patients with colorectal cancer and microsatellite instability.
26096739
2015
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Hereditary Nonpolyposis Colorectal Cancer
0.900
CausalMutation
CLINVAR
Clinical and Molecular Characterization of Brazilian Patients Suspected to Have Lynch Syndrome.
26437257
2015
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Hereditary Nonpolyposis Colorectal Cancer
0.900
GeneticVariation
CLINVAR
RNA splicing. The human splicing code reveals new insights into the genetic determinants of disease.
25525159
2015
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Hereditary Nonpolyposis Colorectal Cancer
0.900
GeneticVariation
CLINVAR
Evidence for presence of mismatch repair gene expression positive Lynch syndrome cases in India.
25420488
2015
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Hereditary Nonpolyposis Colorectal Cancer
0.900
GeneticVariation
CLINVAR
Evaluation of CADD Scores in Curated Mismatch Repair Gene Variants Yields a Model for Clinical Validation and Prioritization.
25871441
2015
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Hereditary Nonpolyposis Colorectal Cancer
0.900
CausalMutation
CLINVAR
Genetic and clinical determinants of constitutional mismatch repair deficiency syndrome: report from the constitutional mismatch repair deficiency consortium.
24440087
2014
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Hereditary Nonpolyposis Colorectal Cancer
0.900
GeneticVariation
CLINVAR
Application of a 5-tiered scheme for standardized classification of 2,360 unique mismatch repair gene variants in the InSiGHT locus-specific database.
24362816
2014
×
Entrez Id:
4292
Gene Symbol:
MLH1
MLH1
Hereditary Nonpolyposis Colorectal Cancer
0.900
CausalMutation
CLINVAR
Application of a 5-tiered scheme for standardized classification of 2,360 unique mismatch repair gene variants in the InSiGHT locus-specific database.
24362816
2014