Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
0.400 Biomarker LHGDN MUC4 mucin interacts with and stabilizes the HER2 oncoprotein in human pancreatic cancer cells. 18381409

2008

Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
0.400 GeneticVariation LHGDN In particular, 3 of 4 adenocarcinomas with EGFR mutations (all L858R point mutations in women, never or former smokers) had a concomitant and identical mutation in AAH, and 2 of 4 adenocarcinomas with K-ras mutations (both at codon 12 in women, a never and a current smoker) showed the same mutation in concomitant AAH.All cases were wild-type for HER2. 18208799

2008

Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
0.400 AlteredExpression LHGDN Tubular carcinoma and grade 1 (well-differentiated) invasive ductal carcinoma: comparison of flat epithelial atypia and other intra-epithelial lesions. 18801081

2008

Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
0.400 AlteredExpression LHGDN The expression rate of c-erbB-2 was higher in adenomas (91%) than adenocarcinomas (30%). 18172343

2007

Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
0.400 GeneticVariation LHGDN In situ and invasive components of mammary adenocarcinoma: comparison of Her-2/neu status. 17879632

2007

Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
0.400 Biomarker LHGDN Here, we show that ErbB2 and Muc4 bind in signet ring carcinoma cells, which was not seen in highly differentiated adenocarcinoma cell lines. 17292332

2007

Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
0.400 AlteredExpression LHGDN Potential prognostic significance of p185(HER2) overexpression with loss of PTEN expression in gastric carcinomas. 16457151

2006

Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
0.400 Biomarker LHGDN Our results indicate that a subset of pancreatic ductal adenocarcinomas is characterized by HER2/neu gene amplification. 16685109

2006

Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
0.400 AlteredExpression LHGDN Alterations of the CCND1 and HER-2/neu (ERBB2) proteins in esophageal and gastric cancers. 16490596

2006

Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
0.400 AlteredExpression LHGDN Cyclooxygenase-2 induces EP1- and HER-2/Neu-dependent vascular endothelial growth factor-C up-regulation: a novel mechanism of lymphangiogenesis in lung adenocarcinoma. 14744769

2004

Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
0.400 AlteredExpression LHGDN Expression levels of p21(WAF1/CIP1) and HER-2/neu were examined imunohistochemically and the amplification of HER-2/neu gene was evaluated by fluorescence in situ hybridisation in HER-2/neu overexpressing adenocarcinomas. 15190415

2004

Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
0.400 AlteredExpression LHGDN We examined the clinicopathological significance of the expression and localization of EGFr and HER-2 in both invasive and intraductal components of ductal adenocarcinomas of the pancreas. 15211117

2004

Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
0.400 AlteredExpression LHGDN Immunohistological study of NM 23 and C-erbB-2 expression in primary tumor and metastases of colorectal adenocarcinoma. 12910292

2003

Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
0.400 AlteredExpression LHGDN Expression of c-erbB-2 oncogene protein, epidermal growth factor receptor, and TGF-beta1 in human pancreatic ductal adenocarcinoma. 14607699

2002

Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
CUI: C0001418
Disease: Adenocarcinoma
Adenocarcinoma
0.400 AlteredExpression LHGDN Evaluation of HER-2/neu gene amplification and protein expression in non-small cell lung carcinomas. 11986780

2002